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1002 articles

August 202624

Case ReportEndocrinology

Neonatal Hyperthyroidism: Case Report and Literature Review.

A late preterm infant presented with thyrotoxicosis due to maternal Graves disease, which had been treated with radioactive iodine.

MCN Am J Matern Child NursAug 13, 2026Read case
Clinical ResearchPsychiatry

Can fluoxetine's diminished efficacy in pediatric depression be explained by study sites, baseline severity, age, and psychological interventions? A secondary exploratory meta-regression.

This meta-analysis explored factors potentially explaining the declining efficacy of fluoxetine in pediatric depression, focusing on study site number, age, baseline severity, and psychological interventions.

J Psychiatr ResAug 13, 2026Read summary
Clinical ResearchPlastic Surgery

Factors influencing shared decision-making in microtia reconstruction: A systematic review.

This systematic review examined factors influencing shared decision-making (SDM) in pediatric microtia reconstruction, analyzing 235 participants including patients, caregivers, and healthcare providers.

Int J Pediatr OtorhinolaryngolAug 13, 2026Read summary
Case ReportMedical Genetics

Expanding the clinical and molecular spectrum of SETD5, NEDD4L, and TBL1X related disorders: A case report and literature review.

A male child presented with a complex phenotype including intellectual disability, seizures, periventricular nodular heterotopia (PVNH), congenital central hypothyroidism, and multiorgan malformations.

GeneAug 13, 2026Read case
Clinical ResearchPediatrics

Efficacy and safety of drinking ice-carbonated water and ice-purified water immediately after extubation in paediatric patients with congenital heart disease: A randomised, controlled three-arm trial.

This randomized controlled trial evaluated the efficacy and safety of ice-carbonated water and ice-purified water in alleviating thirst in 108 children aged 3-12 years post-congenital heart disease surgery.

Aust Crit CareAug 13, 2026Read summary
Case ReportPediatricsOpen access

Disseminated Ganciclovir-Resistant Cytomegalovirus in a Nontransplant Pediatric ALL Patient: A Case Report.

An 8-year-old patient with T-ALL on maintenance chemotherapy developed significant CMV viremia without initial end-organ disease, which progressed to ganciclovir-resistant CMV infection.

J Pediatr Hematol OncolAug 13, 2026Read case
Clinical ResearchPediatrics

Seroefficacy of a 10-valent pneumococcal conjugate vaccine (Pneumosil®) compared with other pneumococcal conjugate vaccines in children.

This randomized controlled trial evaluated the seroefficacy of the 10-valent pneumococcal conjugate vaccine (PCV10 SII) in 716 infants compared to PCV10 GSK and PCV13.

VaccineAug 12, 2026Read summary
Clinical ResearchAnesthesiology

EEG-Guided Sevoflurane Anesthesia and Emergence Delirium in Children: A Randomized Controlled Trial.

This randomized controlled trial evaluated EEG-guided anesthesia using SedLine in 100 children aged 4-10 undergoing dental procedures.

Paediatr AnaesthAug 12, 2026Read summary
Clinical ResearchAnesthesiology

Pre-Extubation Low-Dose Propofol in Pediatric Ear, Nose, and Throat Procedures: A Meta-Analysis With Trial Sequential Analysis.

This meta-analysis evaluated the effects of low-dose propofol before extubation in pediatric patients undergoing ENT procedures. It included ten randomized controlled trials with 414 patients.

Paediatr AnaesthAug 12, 2026Read summary
Case ReportMedical Genetics

Peroxisomal disorder associated with ACOX1 gain-of-function mimicking neuroinflammatory disease.

A 6-year-old girl presented with motor delay, ichthyosiform eczema, gait disturbance, pain, weakness, areflexia, hypomimia, and hearing loss.

Neuromuscul DisordAug 11, 2026Read case
Case ReportPediatricsOpen access

A skeletally immature patient with Diamond-Blackfan anemia with Deferoxamine induced bone dysplasia: An analysis on diffusion tensor imaging.

A 9-year-old boy with Diamond-Blackfan anemia receiving chronic deferoxamine chelation presented with bilateral genu valgum.

Skeletal RadiolAug 11, 2026Read case
Clinical ResearchAllergy & Immunology

Efficacy and safety of nasal saline irrigation for allergic rhinitis in children and adolescents: A systematic review and meta-analysis with GRADE assessment.

This systematic review and meta-analysis evaluated the efficacy and safety of nasal saline irrigation (NSI) for allergic rhinitis in children and adolescents.

Int J Pediatr OtorhinolaryngolAug 10, 2026Read summary
Clinical ResearchPediatrics

The efficacy of oral montelukast versus intranasal fluticasone furoate in reducing the severity of pediatric sleep-disordered breathing: A randomized clinical trial.

This randomized clinical trial evaluated the efficacy of oral montelukast versus intranasal fluticasone furoate in reducing sleep-disordered breathing (SDB) severity in children aged 2-15 with adenotonsillar…

Int J Pediatr OtorhinolaryngolAug 10, 2026Read summary
Clinical ResearchPsychiatry

Adversity profiles among Canadian families: A secondary data analysis of a randomized controlled trial of the Family Check-Up®.

This randomized controlled trial analyzed data from 206 Canadian families to explore the effectiveness of the Family Check-Up® (FCU®) across different adversity profiles.

Dev PsychopatholAug 10, 2026Read summary
Clinical ResearchPediatrics

Examining Sex-Based Inequities in Pediatric Sports Medicine Research: A Systematic Review.

This Level IV systematic review examined sex-based inclusion in original pediatric sports medicine research published from 2020 to 2024 in 12 interdisciplinary journals.

J Pediatr OrthopAug 10, 2026Read summary
Case ReportDermatology

Generalized Laser-Induced Erythema Under General Anesthesia in Infants: A Case Series.

During Q-switched ruby laser treatment under general anesthesia, three infants—two with nevus of Ota and one with ectopic Mongolian spots—developed rapidly spreading generalized erythema.

Lasers Surg MedAug 10, 2026Read case
Clinical ResearchPulmonology

Feedback-enhanced electronic monitoring for asthma inhaler adherence: A systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis of randomized controlled trials assessed feedback-enhanced electronic inhaler monitoring versus standard care in people with asthma.

Int J Nurs StudAug 10, 2026Read summary
Clinical ResearchPediatricsOpen access

"Accessible and Acceptable" Drop-In Mental Health Services for Children With Long-Term Conditions: A Mixed-Methods Exploratory Analysis of Integrated Services From a Health Equity Perspective.

This mixed-methods exploratory analysis evaluated drop-in mental health services for children with long-term conditions across six pediatric healthcare settings.

Clin Child Psychol PsychiatryAug 9, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

The impact of corticosteroid therapy on clinical outcomes in paediatric deep neck space infections: A meta-analysis.

This meta-analysis examined the impact of corticosteroid therapy on clinical outcomes in pediatric patients with deep neck space infections (DNSIs).

Int J Pediatr OtorhinolaryngolAug 8, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Comparison of Iodinated Contrast Doses Based on Total Body Weight and Lean Body Weight in Pediatric Patients: Impact on Image Quality and Contrast Exposure.

This randomized controlled trial evaluated iodinated contrast dosing in 66 pediatric patients (ages 0-16) undergoing abdominal CT, comparing lean body weight (LBW) and total body weight (TBW) dosing protocols.

Radiography (Lond)Aug 7, 2026Read summary
Case ReportNeurology

Spectrum of Neurofascin-155 Autoimmune Nodopathy in a Pediatric Cohort: A Single Center Experience.

This single-center pediatric case series described four patients with anti-neurofascin-155 autoimmune nodopathy. All had distal weakness and sensory loss; three also had tremor and sensory ataxia.

Pediatr NeurolAug 7, 2026Read case
Case ReportNeurology

Clinical Profile, Electrophysiology, and Short-Term Outcomes of Pediatric-Onset Autoimmune Nodopathy-A Case Series.

The report describes three children with autoimmune nodopathy associated with antibodies to neurofascin 140, alone or with neurofascin 186.

Pediatr NeurolAug 7, 2026Read case
Case ReportMedical GeneticsOpen access

Clinical and Genetic Profile of One Molecularly Confirmed and One Clinically Suspected Case of LZTR1 -Related Noonan Syndrome.

Two unrelated female pediatric patients were evaluated for LZTR1-related Noonan syndrome. The first patient exhibited isolated short stature and subtle dysmorphic features, with a confirmed heterozygous pathogenic…

Clin GenetAug 6, 2026Read case
Clinical ResearchAnesthesiology

Effects of Esketamine on Emergence Delirium in Children Undergoing Sevoflurane Anesthesia: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis.

This systematic review and meta-analysis evaluated the efficacy of esketamine in preventing emergence delirium in 916 pediatric patients undergoing sevoflurane anesthesia.

Paediatr AnaesthAug 6, 2026Read summary

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