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1064 articles

August 202624

Clinical ResearchGeriatrics

Effectiveness of psychosocial and lifestyle interventions in promoting behaviour change and improving cognitive outcomes in older people with memory concerns: A systematic review.

This systematic review evaluated the effectiveness of psychosocial and lifestyle interventions on behavior change and cognitive outcomes in older adults with memory concerns.

Ageing Res RevAug 12, 2026Read summary
Clinical ResearchPsychiatry

The efficacy of non-invasive brain stimulation interventions in obsessive-compulsive disorder management: A network meta-analysis of randomized controlled trials.

This network meta-analysis evaluated the efficacy of non-invasive brain stimulation (NIBS) interventions for obsessive-compulsive disorder (OCD) in 1456 participants across 42 randomized controlled trials.

Psychiatry ResAug 12, 2026Read summary
Clinical ResearchPsychiatry

Individualized Connectivity-Guided Versus Conventional Targeting of Accelerated Theta-Burst Stimulation in Depression: A Randomized, Double-Blind, Parallel-Design Trial.

This randomized, double-blind trial evaluated the efficacy of individualized connectivity-guided intermittent theta-burst stimulation (iTBS) versus conventional 5-cm targeting in adults aged 18-65 with major depressive…

Am J PsychiatryAug 12, 2026Read summary
Clinical ResearchAnesthesiology

Predictors of post-electroconvulsive therapy delirium: a prospective randomized study from an Indian tertiary care centre.

This randomized controlled trial investigated predictors of early post-electroconvulsive therapy (ECT) delirium in 90 adult patients.

Nord J PsychiatryAug 12, 2026Read summary
Clinical ResearchPsychiatryOpen access

Educational interventions to reduce mental health stigma toward patients among healthcare professionals and trainees: a systematic review of randomised controlled trials.

This systematic review and meta-analysis assessed randomised controlled trials of educational interventions to reduce mental health stigma among healthcare professionals and trainees.

Soc Psychiatry Psychiatr EpidemiolAug 12, 2026Read summary
Clinical ResearchOncology (Medical)

Personalized Sedation Goals for Agitated End-of-Life Delirium: Secondary Analysis of RECORD Trial.

This preplanned secondary analysis of a multicenter, double-blind randomized trial assessed whether treatments achieved caregiver-defined personalized sedation goals in patients with advanced cancer and persistent…

J Pain Symptom ManageAug 12, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Psychological interventions to improve maternal mental health and resilience during pregnancy in the COVID-19 pandemic: a systematic review.

This systematic review evaluated psychological interventions aimed at improving maternal mental health during the COVID-19 pandemic, focusing on pregnant women.

J Psychosom Obstet GynaecolAug 11, 2026Read summary
Clinical ResearchPsychiatry

Effectiveness and implementation of task-sharing cognitive-behavioral interventions for perinatal mental health: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of cognitive-behavioral interventions (CBIs) delivered by nonspecialist providers (NSPs) for perinatal depressive and anxiety symptoms.

Psychiatry ResAug 11, 2026Read summary
Clinical ResearchPsychiatry

Early anxiety prevention through a live, online group-based parenting program: Effectiveness in a randomized controlled trial.

This randomized controlled trial evaluated the effectiveness of a live, online group-based parenting program for reducing anxiety symptoms in behaviorally inhibited children aged three to six years.

Behav Res TherAug 11, 2026Read summary
Clinical ResearchPsychiatry

Intravenous Ketamine reduces psychological pain in suicidal inpatients: A secondary analysis of a six-week randomized placebo-controlled trial.

This secondary analysis of a six-week randomized placebo-controlled trial evaluated the effect of intravenous ketamine on psychological pain in suicidal psychiatric inpatients.

J Affect DisordAug 10, 2026Read summary
Clinical ResearchPsychiatry

Exploratory non-randomized clinical trial of subcutaneous esketamine in treatment-resistant depression: Effects of ketamine-assisted psychotherapy.

This exploratory, non-randomized clinical trial assessed the effects of ketamine-assisted psychotherapy (KAP) in 46 patients with treatment-resistant depression (TRD) receiving subcutaneous esketamine.

J Affect DisordAug 10, 2026Read summary
Clinical ResearchMedical Genetics

Comparative Effectiveness of Pharmacogenomics for Treatment of Depression.

This randomized controlled trial evaluated the effectiveness of pharmacogenomics-guided treatment (PGx+GIT) versus guideline-informed treatment (GIT) alone in 201 individuals with major depressive disorder.

J Clin PsychopharmacolAug 10, 2026Read summary
Clinical ResearchPsychiatry

Effect of cognitive enhancement therapy for early course schizophrenia on gray matter volume: A confirmatory multisite randomized clinical trial.

This multicenter randomized controlled trial investigated the effects of Cognitive Enhancement Therapy (CET) on gray matter volume in 99 participants with early course schizophrenia.

J Psychiatr ResAug 10, 2026Read summary
Clinical ResearchPsychiatryOpen access

Efficacy of a high-frequency repetitive transcranial magnetic stimulation for craving reduction in adolescents with gaming disorder: a 4-week randomized control trial with 24-week follow-up.

This randomized controlled trial evaluated the efficacy of high-frequency repetitive transcranial magnetic stimulation (rTMS) in reducing psychological craving among 80 adolescents with gaming disorder.

Eur Arch Psychiatry Clin NeurosciAug 10, 2026Read summary
Case ReportPsychiatry

Eye Movement Desensitization and Reprocessing (EMDR) for Shame Related Offense Trauma in a Justice Involved Individual Presenting With Active Suicidality and Self-Harm.

A 42-year-old female healthcare worker, serving a prison sentence for theft, presented with active suicidality and self-harm linked to high levels of offense-related shame.

J Clin PsycholAug 10, 2026Read case
Clinical ResearchPsychiatry

Adversity profiles among Canadian families: A secondary data analysis of a randomized controlled trial of the Family Check-Up®.

This randomized controlled trial analyzed data from 206 Canadian families to explore the effectiveness of the Family Check-Up® (FCU®) across different adversity profiles.

Dev PsychopatholAug 10, 2026Read summary
Clinical ResearchPsychiatry

The Use of the Clinical Global Impressions Scale in Psychosocial Interventions for Autism Characteristics: A Systematic Review.

This systematic review evaluated the use of the Clinical Global Impressions (CGI) scale in 22 studies assessing psychosocial interventions for autism characteristics.

AutismAug 9, 2026Read summary
Clinical ResearchPediatricsOpen access

"Accessible and Acceptable" Drop-In Mental Health Services for Children With Long-Term Conditions: A Mixed-Methods Exploratory Analysis of Integrated Services From a Health Equity Perspective.

This mixed-methods exploratory analysis evaluated drop-in mental health services for children with long-term conditions across six pediatric healthcare settings.

Clin Child Psychol PsychiatryAug 9, 2026Read summary
Case ReportNeurology

Multimodal circadian phenotyping reveals distinct mechanisms of photic entrainment failure in two sighted patients with non-24-hour sleep-wake disorder.

Two sighted patients with non-24-hour sleep-wake disorder (N24SWD) underwent extensive circadian phenotyping to explore mechanisms of photic entrainment failure.

Sleep MedAug 9, 2026Read case
Clinical ResearchRheumatologyOpen access

Stigma, discrimination-related events, and determinants among adult people living with systemic lupus erythematosus (SLE): Systematic review and indicator-level meta-analysis.

This systematic review and meta-analysis examined stigma and discrimination among 2254 adults with systemic lupus erythematosus (SLE).

LupusAug 8, 2026Read summary
Clinical ResearchPsychiatry

Effects of prospective mental imagery on approach motivation and behavioral engagement in social anxiety.

This randomized controlled trial examined the effects of prospective mental imagery on approach motivation and behavioral engagement in socially anxious individuals (N = 136).

Behav Res TherAug 8, 2026Read summary
Clinical ResearchPsychiatry

Cognitive-behavioral suicide prevention for psychosis in community mental health: A pilot randomized clinical trial.

This pilot randomized clinical trial evaluated Cognitive-Behavioral Suicide Prevention for psychosis (CBSPp) plus services as usual (SAU) versus SAU alone among adults with schizophrenia spectrum disorders receiving…

Schizophr ResAug 8, 2026Read summary
Clinical ResearchPsychiatryOpen access

Childhood emotional maltreatment and trauma-related outcomes: a systematic review and multilevel meta-analysis.

This systematic review and multilevel meta-analysis examined the association between childhood emotional maltreatment (CEM) and trauma-related outcomes, specifically PTSD and complex PTSD, across 323,776 participants.

Eur J PsychotraumatolAug 7, 2026Read summary
Clinical ResearchPsychiatry

Social functioning and formal thought disorder in schizophrenia: A Bayesian meta-analysis.

This systematic review and Bayesian random-effects meta-analysis examined associations between positive and negative formal thought disorder (FTD) and social functioning in people with schizophrenia.

Schizophr ResAug 7, 2026Read summary

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