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93 articles
September 20267
Epidemic Thunderstorm Asthma in China: A Systematic Review of an Artemisia-Associated Phenotype.
This systematic review examines epidemic thunderstorm asthma (ETSA) in China, focusing on its association with Artemisia pollen.
Levocetirizine-induced paradoxical fixed drug eruption: A case report with causality assessment.
A patient developed a fixed drug eruption (FDE) after self-medicating with levocetirizine, presenting with hyperpigmented patches that progressed to blisters.
Recurrent severe cutaneous reaction to fluoroquinolones and rifampicin in a human immunodeficiency virus-positive patient with disseminated tuberculosis: A rare case report.
A 47-year-old male with HIV and disseminated tuberculosis experienced recurrent maculopapular eruptions with mucosal involvement after exposure to multiple medications, including fluoroquinolones and rifampicin.
Chronic autoimmune urticaria with worsening during the luteal phase suggestive of progesterone hypersensitivity successfully treated with rituximab.
A 30-year-old woman with glucocorticoid-dependent chronic spontaneous urticaria (CSU) presented with cyclical worsening of symptoms during her luteal phase.
Pharmacokinetic and Pharmacodynamic Bio-Similarity of ADL-018 to Innovator Omalizumab: A Randomized Study in Healthy Adults.
This randomized controlled trial evaluated the pharmacokinetic and pharmacodynamic bio-similarity of ADL-018, a biosimilar to omalizumab, in 306 healthy adults.
Suspected menopause nutraceutical-induced eosinophilic ascites: a rare clinical presentation.
A middle-aged woman presented with a 2-month history of ascites and marked peripheral eosinophilia (49%). Analysis of her ascitic fluid revealed 90% eosinophils, with no malignancy detected.
Asthma Exacerbation Risk and School Asthma Readiness.
This randomized controlled trial evaluated school asthma readiness and its association with asthma exacerbations in a cohort of 202 children aged 5 to 13 years, predominantly Black and non-Hispanic.
August 20266
A novel FLNA p.Pro2469Ser variant is associated with impaired T and NK cell function and immune dysregulation.
FLNA encodes filamin A, a ubiquitously expressed actin-binding cytoskeletal protein that cross-links actin filaments and links them to membrane-associated signaling complexes.
Long-term outcomes of anti-CD19 CAR T cell therapy in refractory myasthenia gravis: A case series.
Three patients with severe, treatment-resistant myasthenia gravis (MG) were treated with autologous anti-CD19 CAR T cell therapy.
Symptom burden to characterise, predict, and prevent asthma attacks: a patient-level meta-analysis of randomised trials and translational prospective studies.
This patient-level meta-analysis evaluated the prognostic value of symptom burden, measured by the ACQ-5, in predicting severe asthma attacks among 7161 participants from various studies.
A multiple ascending dose, phase1b study to evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of lesigercept, a long-acting IgE Trap -Fc fusion protein, in participants with atopy or allergic diseases.
This phase 1b randomized controlled trial evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of lesigercept in adults with atopy or allergic diseases.
Immunomodulatory effects of palm-derived tocotrienol-rich fraction in healthy volunteers following influenza vaccination: A randomised clinical trial.
This randomized controlled trial evaluated the immunomodulatory effects of palm-derived tocotrienol-rich fraction (TRF) on the immune response to influenza vaccination in 150 healthy adults.
Efficacy and safety of nasal saline irrigation for allergic rhinitis in children and adolescents: A systematic review and meta-analysis with GRADE assessment.
This systematic review and meta-analysis evaluated the efficacy and safety of nasal saline irrigation (NSI) for allergic rhinitis in children and adolescents.
July 202611
Epitope-specific IgE profiles are predictive of desensitization and remission in the IMPACT trial.
The IMPACT trial, a randomized controlled trial, evaluated the predictive value of epitope-specific IgE profiles for desensitization and remission in children undergoing peanut oral immunotherapy (pnOIT).
Allergic contact dermatitis after laser-assisted photodynamic therapy with 5-aminolevulinic acid: evidence of cross-sensitization to methyl aminolevulinate.
A 67-year-old male developed severe eczematous dermatitis after laser-assisted photodynamic therapy using 5-aminolevulinic acid for actinic keratoses.
Recreational Allergic Contact Dermatitis to "Epoxy UV" Resins: A New Source of Exposure to Hidden (Meth)acrylates.
Three people developed eczematous eruptions after using products labelled “epoxy UV” resin to make jewellery. Patch testing showed sensitization to (meth)acrylates, but not to the epoxy compounds tested.
Efficacy and safety of press-needle therapy for allergic rhinitis in children: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of press-needle therapy for allergic rhinitis in children, analyzing 24 randomized controlled trials with 1625 participants.
Marked IgE elevation and eosinophilia in a COPD patient ultimately diagnosed with mycobacterium intracellulare pulmonary disease.
A 65-year-old man with COPD presented with persistent eosinophilia and significantly elevated total IgE levels. Initial evaluations for allergic diseases were negative.
Defining Minimal Clinical Disease Activity and Remission in Severe Asthma: A Modified Delphi Consensus.
This systematic literature review and modified Delphi consensus sought to standardize definitions of minimal clinical disease activity and remission in severe asthma.
Stapokibart reduces blood eosinophil counts in patients with moderate-to-severe atopic dermatitis: a post-hoc analysis from phase II and phase III clinical trials.
This post-hoc analysis from phase II and III trials evaluated the impact of stapokibart on blood eosinophil counts in patients with moderate-to-severe atopic dermatitis.
Early response to ivarmacitinib and its impact on long-term efficacy in patients with moderate-to-severe atopic dermatitis: a post hoc analysis of a phase-III trial.
This post hoc analysis of a phase III randomized controlled trial evaluated the early response to ivarmacitinib in 225 patients with moderate-to-severe atopic dermatitis.
Long-term efficacy and safety of dupilumab in patients enrolled from Latin American centers from the open-label extension LIBERTY ASTHMA TRAVERSE study.
This post hoc analysis of the open-label extension TRAVERSE study examined long-term dupilumab outcomes in patients with moderate-to-severe asthma enrolled at Latin American centers after completing a phase 2b or phase…
Bivariate analysis of symptom and medication score effect sizes in grass pollen allergen immunotherapy reveals route-dependent dissociation: implications for the combined symptom and medication score.
This meta-analysis examined the relationship between symptom scores (SS) and medication scores (MS) in 14 randomized controlled trials of grass pollen allergen immunotherapy (AIT) involving 4850 patients.
Postmortem tryptase as a diagnostic marker in fatal anaphylaxis: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated postmortem serum tryptase as a diagnostic marker in fatal anaphylaxis, analyzing data from seven studies involving 105 anaphylactic deaths and 449 controls.
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