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323 articles
October 202623
Comparative efficacy of topical garlic extract and 20% podophyllin solution in the treatment of female genital warts: a triple-blind randomized clinical trial.
This triple-blind randomized clinical trial compared topical 5% garlic extract with 20% podophyllin in 74 women with genital warts, applied weekly for four weeks.
Lamotrigine-associated SJS/TEN overlap during valproate co-therapy managed with rhTNFR-Fc and therapeutic plasma exchange: A case report.
A 49-year-old man receiving valproate developed fever and a rapidly spreading erythematous maculopapular eruption after lamotrigine was started at 50 mg once daily.
Effect of pre-visit computer-assisted history-taking with a structured copy-ready summary on documentation completeness in screening for inflammatory rheumatic diseases: a randomized pilot study.
This multicenter, parallel-group randomized pilot study assessed pre-visit computer-assisted history-taking (CAHT) with a structured, copy-ready summary in adults at increased risk of inflammatory rheumatic disease…
Clinical Efficacy of 5-Aminolevulinic Acid Photodynamic Therapy Combined With Interferon Spray in Treating Common and Plantar Warts.
This randomized controlled trial evaluated the efficacy of 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) combined with recombinant human interferon alpha 2b (rhIFN-α2b) spray in 104 patients with refractory…
Janus kinase inhibitors in the management of lichen planus: a systematic review.
Lichen planus (LP) is a chronic, lymphocytic, inflammatory skin disorder that can affect the skin, hair follicles, nails, and mucous membranes. It has limited treatment options.
A 45-Year-Old Woman With 30-Year History of a Nodule of the Earlobe Diagnosed as Lupus Vulgaris (Cutaneous Tuberculosis).
A 45-year-old woman had a painless, intermittently itchy lesion on her right earlobe for more than 30 years. It appeared as a red, thickened plaque with yellow papules and pustules.
Safety, Efficacy, and Immunogenicity of a Multivalent Adjuvanted Staphylococcus aureus Vaccine in Adults With Recent Skin and Soft Tissue Infections: An Observer-Blind, Randomized, Placebo-Controlled, Multinational Phase 1/2 Trial.
This observer-blind, randomized, placebo-controlled phase 1/2 trial evaluated a five-antigen Staphylococcus aureus vaccine with AS01E adjuvant in adults, including 194 participants aged 18–64 years with a recent S.
Acrokeratosis paraneoplastica (Bazex syndrome): a systematic review and quantitative analysis of 106 cases.
Acrokeratosis paraneoplastica (Bazex syndrome) is an obligate paraneoplastic dermatosis characterized by symmetrical acral psoriasiform lesions and nail dystrophy.
Cutaneous leukocytoclastic vasculitis with concurrent colitis of uncertain aetiology.
A female in her 20s presented with biopsy-confirmed cutaneous leukocytoclastic vasculitis and significant gastrointestinal symptoms, including recurrent rectal bleeding and abdominal pain.
Nephrotic range proteinuria and rapid progression to end-stage kidney disease in seronegative pauci-immune necrotizing glomerulonephritis masked by cutaneous lesions: a case-based review.
A 22-year-old woman with a history of recurrent cutaneous lesions was hospitalized due to exacerbation of her skin condition. Laboratory tests revealed nephrotic-range proteinuria and reduced eGFR.
Geographical and temporal patterns of cutaneous leishmaniasis in Pakistan: insight from a decade of epidemiology.
This systematic review examined the geographical distribution and epidemiological trends of cutaneous leishmaniasis (CL) in Pakistan from 2014 to 2024.
Treatment of hypertrophic scars using fractional CO2 laser alone in comparison with adding botulinium toxin either intalesional injection or assisted drug delivery.
This randomized controlled trial evaluated the effectiveness of fractional CO₂ laser treatment alone versus its combination with botulinum toxin A in 16 patients with post-burn hypertrophic scars.
Advanced therapies for extraintestinal manifestations of IBD: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of advanced therapies (ATs) for extraintestinal manifestations (EIMs) in patients with inflammatory bowel diseases (IBD).
Paraneoplastic dermatomyositis preceding detection of metastatic oesophageal squamous cell carcinoma after prolonged remission following pembrolizumab therapy.
A man in his late fifties with a history of treated oesophageal squamous cell carcinoma developed severe dermatomyositis after six years of remission.
New Primary and Secondary Prevention Measures for Cutaneous Melanoma: A Systematic Review.
This systematic review evaluated recent evidence on primary and secondary prevention strategies for cutaneous melanoma, analyzing 24 studies.
Long-Term Safety and Efficacy of Dazukibart in Dermatomyositis: Combined Phase II Results From Double-Blind and Open-Label Extension Studies.
This study evaluated the long-term safety and efficacy of dazukibart, an antiinterferon β monoclonal antibody, in adults with moderate-to-severe dermatomyositis through a combined Phase II randomized controlled trial…
INDIVIDUAL ARTICLE: Tildrakizumab for Real-World Psoriasis Care: Clinical Lessons From Medically Complex and Underserved Patient Populations.
This case review discusses 16 patients with moderate-to-severe plaque psoriasis treated with tildrakizumab, a monoclonal antibody targeting interleukin-23.
Cicatricial Ectropion in the Setting of IL-13 Inhibition.
An 81-year-old man with extensive atopic dermatitis was treated with dupilumab, leading to significant improvement. However, he later developed ocular symptoms and inferior cicatricial ectropion of the left lower eyelid.
Contact Allergens Associated With Nummular Eczema: A Systematic Review.
This systematic review examined the association between contact allergens and nummular eczema (NE) by analyzing 10 observational studies.
Pulsed Dye Laser for Sensory Dysesthesias Associated With Chronic Radiation Dermatitis.
Two breast cancer patients with chronic radiation dermatitis (CRD) presented with debilitating sensory dysesthesias unresponsive to conventional treatments.
Biologics and Small-Molecule Inhibitors for the Treatment of Nummular Eczema: A Systematic Review.
This systematic review evaluated the efficacy of biologics and small-molecule inhibitors for treating nummular eczema (NE) by analyzing 10 studies.
Use of a Synthetic Polylactic Acid Matrix for Pyoderma Gangrenosum: A Case Series.
This case series involved six patients with chronic, non-healing ulcers due to pyoderma gangrenosum, persisting for 6 months to 3 years.
Histological Analysis Shows That a Moisturizer Formulated for Dermatoporosis Increases Elastin Content and Improves Skin Elasticity.
This multicenter clinical trial evaluated the effects of a novel moisturizer (GC cream) on skin biomarkers in individuals aged 40 to 60 with dermatoporosis.
September 20261
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