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1022 articles
August 202624
Prevalence and Clinical Relevance of Antiphospholipid Antibodies in Ischemic Stroke: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the prevalence of antiphospholipid antibodies (aPL) in patients with ischemic stroke. Among 9438 patients, the pooled prevalence of aPL seropositivity was 19.1%.
Multistrain probiotics modulate tau pathology and preserve visuospatial cognition in early cognitive impairment: A double-blind, randomized, placebo-controlled trial.
This randomized, double-blind, placebo-controlled trial investigated the effects of a multistrain probiotic supplement on plasma biomarkers and cognitive function in 87 older adults with early cognitive impairment.
Therapeutic Prospects of Ketamine for Cataplexy in Narcolepsy Type 1: Evidence from a Human Case and a Murine Model.
A 34-year-old man with narcolepsy type 1 and cataplexy could not tolerate standard therapies. Morning intranasal ketamine was associated with a marked, sustained reduction in cataplexy; symptoms recurred after ketamine…
Stroke risk following BNT162b2 vaccination: a systematic review and meta-analysis of self-controlled case series studies.
This meta-analysis evaluated the stroke risk associated with BNT162b2 vaccination using self-controlled case series studies. It included eight studies from six countries with several million vaccinated individuals.
Child Neurology: Radiologic Evolution and Developmental Correlates in Fetal Cerebral Sinovenous Thrombosis: A Case Report.
This case report discusses two children diagnosed with fetal cerebral sinovenous thrombosis (CSVT) via fetal MRI. Serial neuroimaging revealed significant evolution in cerebrovascular pathology, including changes in…
Delayed appearance of bilateral cerebral peduncle lesions in autoimmune glial fibrillary acidic protein astrocytopathy: A serial MRI case series.
Three patients with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) underwent serial MRI to assess brain lesions.
Diagnostic value of serum neuron-specific enolase and S100 calcium-binding protein B for sepsis-associated encephalopathy: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether serum neuron-specific enolase (NSE) and S100 calcium-binding protein B (S100B) distinguish sepsis-associated encephalopathy (SAE) from sepsis without SAE.
Body Weight in Relation to the Effectiveness of Intravenous Alteplase in Acute Ischemic Stroke: The ENCHANTED Trial.
This post hoc analysis of the ENCHANTED trial evaluated the impact of body weight on the effectiveness of low- versus standard-dose intravenous alteplase in 4,458 patients with acute ischemic stroke.
Mitochondrial abnormalities in Charcot-Marie-Tooth disease: insights from a family harbouring a novel GDAP1 variant.
Charcot-Marie-Tooth disease is an inherited peripheral neuropathy marked by progressive loss of motor and sensory function.
Effects of neurofeedback and biofeedback on cognitive, affective, and motor outcomes in adults with multiple sclerosis: a systematic review.
This systematic review examined interventional studies of neurofeedback and biofeedback for cognitive, affective, and motor outcomes in adults with multiple sclerosis.
Corpus callosotomy in Lennox-Gastaut syndrome: Effectiveness, safety, and predictors of outcome: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed corpus callosotomy (CC) effectiveness and safety for Lennox-Gastaut syndrome (LGS), synthesizing 48 studies involving 822 patients.
Myelin Oligodendrocyte Glycoprotein Antibodies in Breast Milk in a Lactating Woman With Severe Enterovirus-Associated MOGAD.
A 38-year-old lactating woman presented with severe MOGAD following enterovirus gastroenteritis. She developed a rapid decline into coma with status epilepticus, necessitating intensive care.
Management of ketogenic diet therapy in patients with ileostomy: A report of 2 cases.
This case series discusses two pediatric patients with medication-resistant epilepsy who underwent ketogenic diet therapy (KDT) while managing ileostomies.
Neuroimaging correlates of pain in Parkinson's disease: A systematic review of structural and resting-state fMRI studies.
This systematic review examined neuroimaging studies to understand pain mechanisms in Parkinson's disease (PD). It included 432 PD patients with pain, 225 without pain, and 257 healthy controls.
Efficacy and safety of MR guided-laser interstitial thermal therapy versus resective surgery for MRI-positive focal cortical dysplasia type II and tuberous sclerosis complex: A systematic review and meta-analysis.
This systematic review and meta-analysis compared the efficacy and safety of magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) and resective surgery in patients with MRI-positive focal cortical…
Clinicopathological characterisation of the first Australian family with the p.G51D SNCA mutation.
A family carrying the p.G51D SNCA mutation was identified through a community study of young-onset dementia. The proband developed parkinsonism at 38, followed by cognitive difficulties at 41 that progressed to dementia.
Resting-state EEG spectral power alterations following traumatic brain injury: a comprehensive systematic review and meta-analysis of clinical and injury-related moderators.
This systematic review and meta-analysis examined resting-state EEG spectral power after traumatic brain injury (TBI), including whether clinical and injury-related factors moderated findings.
Bilateral Orbital Fat Hyperintensity in Early Glial Fibrillary Acidic Protein Astrocytopathy: A Case Report.
A 26-year-old woman presented with headache, fever, and bilateral ocular pain. MRI revealed hyperintensity in the bilateral orbital fat without optic nerve involvement, while initial intracranial MRI was unremarkable.
Safety, tolerability, and efficacy of alixorexton, a selective orexin 2 receptor agonist for narcolepsy type 1 (Vibrance-1): a randomised, double-blind, placebo-controlled, phase 2 trial.
This phase 2 randomized, double-blind, placebo-controlled trial evaluated the safety, tolerability, and efficacy of alixorexton, an orexin 2 receptor agonist, in 92 adults with narcolepsy type 1.
Pure visuospatial neglect due to cingulum bundle disconnection in right anterior cerebral artery infarction: a case report with diffusion tensor imaging analysis.
A 62-year-old woman experienced cognitive decline, including perseverative behavior and disorientation, following a right medial frontal acute infarction due to anterior cerebral artery occlusion.
Comparative efficacy and safety of rosuvastatin versus atorvastatin after acute ischemic stroke or transient ischemic attack: A systematic review and exploratory meta-analysis.
This systematic review and exploratory meta-analysis evaluated the efficacy and safety of rosuvastatin versus atorvastatin in patients following acute ischemic stroke (AIS) or transient ischemic attack (TIA).
Diagnostic value of blood p-tau subtypes in Alzheimer's disease progression and pathology: systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic value of blood phosphorylated-tau (p-tau) subtypes in Alzheimer's disease (AD) progression and pathology.
Early and prolonged oral edaravone for neuroprotection in acute ischemic stroke: the ERASE-STROKE randomized controlled phase 3 trial.
The ERASE-STROKE trial evaluated the effects of early and prolonged oral edaravone (TTYP01) on functional outcomes in patients with acute ischemic stroke.
Ambient air pollution exposure and cognitive aging, mediators and possible pathways: A systematic review on the epidemiological studies.
This systematic review examined epidemiological evidence on factors that may mediate associations between ambient air pollution and cognitive aging.
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