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1022 articles
August 202624
A systematic review and meta-analysis of the efficacy and safety of eculizumab in AQP4-IgG-positive neuromyelitis optica spectrum disorder.
This systematic review and meta-analysis assessed eculizumab efficacy and safety in people with AQP4-IgG-positive neuromyelitis optica spectrum disorder, including phase III randomised controlled trials.
Neurocognitive deficits in children with polysomnographically confirmed obstructive sleep apnea: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated neurocognitive deficits in school-aged children (mean age 5-12 years) with polysomnographically confirmed obstructive sleep apnea (OSA).
Long-term outcomes of anti-CD19 CAR T cell therapy in refractory myasthenia gravis: A case series.
Three patients with severe, treatment-resistant myasthenia gravis (MG) were treated with autologous anti-CD19 CAR T cell therapy.
Risk of post-acute symptoms and conditions after SARS-CoV-2 compared with other respiratory viral infections: a systematic review and meta-analysis.
This systematic review and meta-analysis compared persistent symptoms and conditions in adults after SARS-CoV-2 infection with those following other acute respiratory viral infections.
Effect of Baseline ASPECTS on Tenecteplase Efficacy Before Thrombectomy in Acute Large-Vessel Occlusion Stroke: A Post Hoc Analysis of the BRIDGE-TNK Randomized Trial.
This post hoc analysis of the BRIDGE-TNK randomized trial evaluated the impact of baseline ischemic extent, measured by ASPECTS, on the efficacy of intravenous tenecteplase before thrombectomy in 550 patients with acute…
Systematic Review on Noncomputed Tomography-Based Technologies for Prehospital Stroke Diagnosis.
This systematic review evaluated noncomputed tomography-based technologies for prehospital stroke diagnosis, analyzing 105 publications.
Colchicine for Secondary Prevention After Stroke According to the Presence of Atherosclerosis.
This randomized controlled trial analyzed the effects of colchicine for secondary prevention of major adverse cardiovascular events (MACEs) after stroke, focusing on patients with and without atherosclerosis.
Meta-analysis and pharmacoeconomic study of rasagiline versus selegiline in the treatment of Parkinson's disease.
This meta-analysis evaluated the efficacy, safety, and cost-effectiveness of rasagiline versus selegiline in early-stage Parkinson's disease using data from ten randomized controlled trials.
Digital mental health screening within neurological clinical healthcare settings: a systematic review.
This systematic review evaluated the implementation of digital mental health screening in neurology healthcare settings, analyzing 31 studies across various neurological disorders.
Serum Lipoprotein(a) and Hemorrhagic stroke risk: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the relationship between serum lipoprotein(a) [Lp(a)] levels and hemorrhagic stroke risk in adults.
A systematic review exploring the link between chronic venous disease and neuropathy.
This systematic review examined objective evidence of neuropathy in patients with chronic venous disease (CVD), excluding studies involving comorbidities that predispose to peripheral neuropathy.
Identification and characterisation of a novel homozygous KDM5A variant associated with severe axial hypotonia, seizures, and cardiac anomalies.
A patient with severe neurodevelopmental delay had neuromotor delay, profound axial hypotonia with absent head control, mild upper-limb spasticity, a history of seizures, facial dysmorphism and congenital heart disease.
Non-invasive brain stimulation increases default mode network functional connectivity in a patient with Posterior Cortical Atrophy.
A patient with Posterior Cortical Atrophy (PCA) and memory impairments underwent individualized intermittent theta burst stimulation (iTBS) targeting the left caudal middle frontal gyrus.
Exercise with motor cortex high-definition transcranial direct current stimulation enhances cardiovascular efficiency and lower-limb function in multiple sclerosis: A crossover, double-blind, and proof-of-principle study.
This crossover randomized controlled trial investigated the effects of exercise combined with high-definition transcranial direct current stimulation (HD-tDCS) in individuals with Multiple Sclerosis (MS).
Clinical features of four unrelated Japanese patients with autosomal recessive spinocerebellar ataxia type 32.
Four unrelated Japanese patients with autosomal recessive spinocerebellar ataxia type 32 (SCAR32) were identified among 411 ataxia cases negative for repeat expansion disorders.
Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy.
A 3-month-old male presented with fever, lymphadenopathy, and macrocephaly due to multiple dural-based masses causing obstructive hydrocephalus.
Comparative Evaluation of Virtual Reality versus Standard Nursing Care in Managing Pain and Fear during Lumbar Puncture Procedures: A Randomised Controlled Trial.
This randomized controlled trial evaluated the effectiveness of virtual reality (VR) in reducing pain and fear during lumbar punctures in 85 adults.
Diagnostic communication in functional neurological disorder: A systematic review and meta-analysis of patient acceptance and clinical outcomes.
This systematic review and meta-analysis evaluated diagnostic communication in adults with Functional Neurological Disorder (FND).
Diagnostic accuracy of a self-administered digital cognitive test battery for differentiating early Alzheimer's disease from controls.
This clinical trial evaluated the diagnostic accuracy of BraincheX, a self-administered digital cognitive test, in distinguishing early Alzheimer's disease (AD) from cognitively healthy controls.
Post-endovascular thrombectomy perfusion imaging (CT and MR) as a prognostic biomarker and patient-selection tool for adjuvant therapy: A systematic review, meta-analysis, and clinical threshold framework.
This systematic review and meta-analysis evaluated post-endovascular thrombectomy (EVT) perfusion imaging as a prognostic biomarker for functional independence in patients with large vessel occlusion stroke.
Prevalence of epilepsy and seizures in frontotemporal dementia: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence of epilepsy and seizures in individuals with frontotemporal dementia (FTD).
Early Ictal Dynamics in Childhood Absence Epilepsy: Scalp EEG Detection of Direct Current Shifts and High-Frequency Oscillations.
Two children with childhood absence epilepsy had typical absence seizures during hyperventilation-provoked scalp EEG. Wide-band recordings captured both direct-current (DC) shifts and high-frequency oscillations (HFOs)…
Virtual reality interventions and their impact on physical function and quality of life in multiple sclerosis: A systematic review with meta-analysis.
This systematic review and meta-analysis pooled randomized controlled trials of structured virtual reality (VR) rehabilitation in adults with multiple sclerosis.
Paucibacillary tuberculous meningitis with clinical-radiological dissociation: A diagnostic challenge.
A 63-year-old woman with newly diagnosed diabetes presented with stroke-like symptoms, including hemiparesis and aphasia, but lacked typical signs of infection.
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