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782 articles
June 202624
Effect of a community-based behavioural intervention bundle to improve antibiotic use and patient management in Burkina Faso and DR Congo (CABU-EICO): a cluster-randomised controlled trial.
This cluster-randomised controlled trial evaluated a community-based intervention in Burkina Faso and DR Congo aimed at reducing Watch-group antibiotic use among healthcare providers.
Sero-Diagnosis of Scrub Typhus Infection in India: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prevalence of scrub typhus among patients with acute febrile illness in India.
Simultaneous purulent pericarditis and acute epiglottitis from Haemophilus influenzae in an immunocompetent adult: a case report.
A 70-year-old female presented to the emergency department with a sore throat and dyspnea, diagnosed with epiglottitis. She rapidly deteriorated, developing shock and acute respiratory failure.
Impact of insecticide-treated nets on malaria morbidity and mortality: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the impact of insecticide-treated nets (ITNs) on malaria incidence and mortality in vulnerable populations.
When the test lies: Fatal cryptococcosis and the prozone effect in advanced HIV infection.
A 37-year-old man with advanced HIV infection presented with altered mental status. Initial cryptococcal antigen (CrAg) tests on serum and cerebrospinal fluid (CSF) were negative.
Hemorrhagic eosinophilic pericardial effusion associated with probable sparganosis.
A 25-year-old man developed hemorrhagic eosinophilic pericardial effusion after consuming undercooked frog meat. Diagnostic workup revealed peripheral eosinophilia and eosinophils in the pericardial fluid, with elevated…
Periprosthetic hip infection by Francisella tularensis.
A 63-year-old man presented with a prosthetic hip joint infection attributed to Francisella tularensis subspecies holarctica after rural exposure.
Time to sputum culture conversion and its predictors among drug-resistant tuberculosis patients in Ethiopia: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the time to sputum culture conversion and its predictors among 2851 drug-resistant tuberculosis patients in Ethiopia.
Bundle implementation for reduction of central venous catheter associated bloodstream infections in pediatric intensive care unit - A systematic review.
This systematic review evaluated the effectiveness of care bundles in reducing central line-associated bloodstream infections (CLABSI) in pediatric intensive care units (PICUs).
Efficacy and safety of maribavir in Japanese patients with post-transplant cytomegalovirus infections: a phase III study.
This phase III, multicenter study evaluated the efficacy and safety of maribavir in Japanese patients aged ≥16 years with cytomegalovirus (CMV) infections post-transplant.
Factors associated with the percentage of individuals who initiate and discontinue naltrexone as a relapse prevention pharmacotherapy in opioid use disorder: A systematic review, meta-analysis and meta-regression.
This systematic review and meta-analysis examined initiation and discontinuation rates of naltrexone for relapse prevention in opioid use disorder (OUD) among 124,016 individuals.
Immunogenicity and safety of AS03-adjuvanted A/Astrakhan/3212/2020 (H5N8)-like influenza vaccine in adults: Phase 1/2, observer-blinded, randomized trial.
This phase 1/2 randomized trial evaluated the immunogenicity and safety of GSK's AS03-adjuvanted H5N8 influenza vaccine in 518 healthy adults.
Advancing protozoan vaccine research: A review of promising candidates and emerging technologies.
This systematic review evaluates the current state of vaccine development against six major protozoan pathogens, including Plasmodium falciparum and Toxoplasma gondii.
Liver Cancer Risk and Incidence Attributable to Human Immunodeficiency Virus: A Meta-Analysis and Population-Attributable Modeling Study of Over 1.2 Million Individuals.
This systematic review and meta-analysis, combined with population-attributable modeling, assessed the association between HIV and liver cancer using studies published from 1984 to 2023 and data covering over 1.2…
Yellow fever vaccination in healthy Gambian children of different ages to establish safety and immunogenicity of a booster dose: a open-label, non-randomised, single-site, phase 3 vaccine trial.
This open-label, non-randomised, single-site, phase 3 trial evaluated the safety and immunogenicity of a yellow fever booster in 610 healthy Gambian children aged 1-9 years.
Vasopressors or Fluids in Early Septic Shock.
This multicenter randomized trial compared restricted-volume intravenous fluids with early vasopressors against higher-volume fluids with later vasopressors in adults presenting to emergency departments with septic…
Safety and immunogenicity of a booster dose of COVAC-2, a Sepivac SWE™ adjuvanted SARS-CoV-2 recombinant protein vaccine in previously vaccinated healthy adults; a randomized controlled multicentre trial.
This Phase 1 randomized controlled trial assessed the safety and immunogenicity of the COVAC-2 vaccine as a heterologous booster in 60 previously vaccinated adults.
Refractory Candida orthopsilosis endocarditis in a hemodialysis patient: The role of species-level identification and surgical source control.
A 60-year-old woman on hemodialysis with diabetes and chronic kidney disease developed catheter-related fungemia that progressed to infective endocarditis caused by Candida orthopsilosis.
Anti-interferon-γ autoantibody syndrome mimicking lymphoproliferative disorders: a case series.
Two patients presented with prolonged fever, weight loss, and generalized lymphadenopathy, initially misdiagnosed as lymphoproliferative disorders based on lymph node biopsies suggesting multicentric Castleman disease…
Prevalence of circulating hepatitis C virus genotypes and drug-resistant variants in former Soviet Union countries: A scoping review with genotype meta-analysis.
This meta-analysis and scoping review examined the prevalence of hepatitis C virus (HCV) genotypes and drug-resistant variants in the Former Soviet Union (FSU) using data from 24 studies.
Cervical tuberculosis mimicking carcinoma of the cervix in a patient with long-standing secondary amenorrhea.
A woman in her 40s with 12 years of secondary amenorrhea presented with postcoital bleeding. Examination showed a cervical growth concerning for carcinoma.
Safety and immunogenicity of 4CMenB and MenACWY-CRM meningococcal vaccines when administered concomitantly in healthy adolescents: A phase 3b, randomized, observer-blind study.
This phase 3b randomized controlled trial evaluated the safety and immunogenicity of co-administering the 4CMenB and MenACWY-CRM meningococcal vaccines in 940 healthy adolescents aged 16-18 years.
A case of atypical orf virus infection of the hand in an immunocompromised patient.
An immunocompromised post-transplant patient presented with an enlarging exophytic mass on the hand, diagnosed as atypical orf virus infection.
Case Series of Cutaneous Rothia Mucilaginosa Infection and an Important Potential Pitfall Case.
Three immunocompromised patients with hematolymphoid malignancies and profound neutropenia presented with suspected cutaneous infections caused by Rothia mucilaginosa.
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