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1002 articles
July 202624
Human versus analogue insulin for children and young adults with type 1 diabetes in low-resource settings (HumAn-1): a multicentre, open-label, randomised controlled trial.
The HumAn-1 trial was a multicentre, open-label, randomised controlled trial assessing insulin glargine versus human isophane insulin in children and young adults with type 1 diabetes in low-resource settings.
Defining neonatal encephalopathy: an international real-time Delphi consensus process.
This study established a consensus definition for neonatal encephalopathy through a real-time Delphi process involving diverse international stakeholders.
Effectiveness of Buzzy® and ShotBlocker® for pain reduction during heel stick procedures in term newborns: A randomized controlled trial.
This randomized controlled trial evaluated the effectiveness of Buzzy® and ShotBlocker® for pain reduction during heel stick procedures in 174 term newborns.
Impact of Physical Environment of Pediatric Inpatient Wards on Children: A Systematic Literature Review.
This systematic literature review examined 30 studies on the physical environments of pediatric inpatient wards, focusing on their impact on health outcomes and experiences of children and families.
Prevalence, Diagnosis, and Treatment of Psychiatric Symptoms After Arterial Ischemic Stroke in Childhood: A Systematic Review.
This systematic review examined the prevalence, diagnosis, and treatment of psychiatric symptoms in 2685 pediatric patients after arterial ischemic stroke (AIS).
Neuromuscular Changes During the Six-Minute Walk Test in Pediatric Sickle Cell Disease.
This clinical trial examined neuromuscular changes during the six-minute walk test (6MWT) in children and adolescents with sickle cell disease (SCD).
GLP-1 receptor agonist therapy in children and adolescents with obesity: A network meta-analysis of differential cardiometabolic efficacy and safety profiles.
This network meta-analysis evaluated the efficacy and safety of GLP-1 receptor agonists (GLP-1RAs) in adolescents with obesity, analyzing 17 randomized clinical trials involving 1230 participants.
Parenteral Lipid Dose and Bilirubin Neurotoxicity in Extremely Preterm Infants: A Factorial Randomized Trial.
This study evaluated the impact of a lower maximum dose of soybean oil lipid emulsion on bilirubin neurotoxicity in extremely preterm infants (<27 weeks or ≤750 g) through a single-center randomized trial.
A pilot randomized feasibility clinical trial of intranasal vs. intravenous naloxone in pediatric opioid poisoning.
This pilot randomized feasibility trial assessed intranasal (IN) versus intravenous (IV) naloxone in children aged 1-12 years with opioid poisoning.
Green heart: Methylene blue administration in a hemodynamically unstable infant following cardiac arrest due to parental co-sleeping.
A 10-month-old female infant experienced cardiocirculatory arrest due to hypoxia from compressive asphyxia related to parental co-sleeping.
Parental childhood vaccination hesitancy and refusal in Türkiye: A systematic review of contributing factors.
This systematic review examined factors influencing parental vaccine hesitancy and refusal in Türkiye, synthesizing evidence from 26 studies.
Prevalence of Breastfeeding in Infants With Down Syndrome: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prevalence of breastfeeding in infants with Down syndrome, analyzing data from 26 studies involving 3463 infants.
Case Report of Changes in Breastfeeding and Alcohol Consumption During the First 6 Months.
This case report details a mother-infant dyad where early pacifier use and scheduled feeding led to decreased breast stimulation and suckling frequency, impacting breastfeeding behavior.
Randomized controlled trial evaluating immunogenicity and safety of a porcine circovirus-free rotavirus vaccine in healthy Chinese infants.
This Phase III randomized controlled trial assessed the immunogenicity and safety of a porcine circovirus-free rotavirus vaccine (Rotarix PCV-free) compared to standard Rotarix in healthy Chinese infants aged 6-16…
Blood-based microRNAs as biomarkers of insulin resistance in childhood obesity: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated blood-based microRNAs (miRNAs) as biomarkers for insulin resistance (IR) in children with obesity.
Vitamin D Deficiency and Severe Dengue Fever: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the relationship between vitamin D deficiency and severe dengue fever across six studies involving 1,130 participants.
The effect of sticker intervention on children's pain and anxiety after invasive procedures.
This randomized controlled trial evaluated the impact of sticker intervention on pain and anxiety in pediatric patients aged 5-10 years after invasive procedures.
Increased 18 F-FDG Avidity on PET/CT During Treatment for Rhabdomyosarcoma Confirmed to Be Mature Rhabdomyoblasts.
An adolescent with metastatic fusion-positive rhabdomyosarcoma exhibited a new 18 F-FDG-PET avid focus in the radiation field during systemic chemotherapy, raising concerns for disease progression.
Reflections on GnRH analogues dosage in the context of escape phenomenon: a case report of hypothalamic hamartoma with central precocious puberty and literature review.
A 15-month-old boy with central precocious puberty due to hypothalamic hamartoma experienced an escape phenomenon during treatment with gonadotropin-releasing hormone analogues.
Infant Dietary Patterns and Early Childhood Weight Outcomes: A Secondary Analysis from the Starting Early Program Trial.
This secondary analysis of a randomized controlled trial involving 377 mother-infant dyads examined the impact of infant dietary patterns on weight outcomes.
South African Paediatric Surgical Outcomes Study-2 (SAPSOS-2): a prospective multi-centre pre-post study evaluating haemoglobin response to oral iron for iron-deficiency anaemia in children undergoing elective noncardiac surgery.
The SAPSOS-2 study evaluated the haemoglobin response to oral iron in children with iron-deficiency anaemia undergoing elective noncardiac surgery in South Africa.
Efficacy and safety of risdiplam in patients with type 1 spinal muscular atrophy: a 3-year open-label extension of the two-part, phase 2 FIREFISH trial.
This study reports the long-term safety and efficacy of risdiplam in children with type 1 spinal muscular atrophy over a 3-year open-label extension of the phase 2 FIREFISH trial.
Open Versus Minimally Invasive Surgery for Congenital Diaphragmatic Hernia Repair: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the safety and efficacy of open surgery (OS) versus minimally invasive surgery (MIS) for congenital diaphragmatic hernia (CDH) repair in pediatric patients.
Integrated genomic and biochemical diagnosis of a novel homozygous start-loss variant in AKR1D1 associated with neonatal cholestasis.
A 3-month-old male presented with severe neonatal cholestasis and elevated tyrosine levels detected in newborn screening. Despite transient normalization of tyrosine, recurrent hyper-tyrosinemia and progressive…
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