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1022 articles

July 202624

Clinical ResearchNeurology

Combining neuromelanin-sensitive MRI and quantitative susceptibility mapping for enhanced diagnosis and differentiation of parkinson's disease: A systematic review.

This systematic review evaluated the diagnostic performance of combining neuromelanin-sensitive MRI (NM-MRI) and quantitative susceptibility mapping (QSM) in Parkinson's disease (PD) across 17 studies involving 2228…

Psychiatry Res NeuroimagingJul 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Infertility treatment in women with epilepsy: A systematic review.

The impact of assisted reproductive technologies (ART) on seizure control in women with epilepsy remains incompletely understood.

Epilepsy BehavJul 23, 2026Read summary
Clinical ResearchNeurology

Valproate vs levetiracetam in juvenile myoclonic epilepsy: systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy and tolerability of valproate (VPA) versus levetiracetam (LEV) in juvenile myoclonic epilepsy (JME) patients.

Epilepsy BehavJul 23, 2026Read summary
Clinical ResearchNeurology

A systematic review and meta-analysis of visuospatial attentional deficits in Parkinson's patients.

This systematic review and meta-analysis investigated visuospatial attentional deficits in right-handed, cognitively unimpaired patients with Parkinson's disease (PD).

Neurosci Biobehav RevJul 23, 2026Read summary
Clinical ResearchNeurologyOpen access

Interstitial fluid rejuvenation through young-donor plasma exchange in cognitively impaired patients: a pilot safety and feasibility study.

This pilot safety and feasibility study evaluated the effects of young-donor plasma exchange in 12 cognitively impaired patients with mild cognitive impairment and Alzheimer's disease biomarkers.

GeroscienceJul 23, 2026Read summary
Clinical ResearchAnesthesiology

Effect of ketofol versus Fentanyl-Midazolam sedation on neurological recovery in traumatic brain Injury: A randomised study.

This randomized controlled trial evaluated the effects of ketofol versus fentanyl-midazolam sedation on neurological recovery in adults with moderate-to-severe traumatic brain injury (TBI).

J Clin NeurosciJul 22, 2026Read summary
Case ReportNeurology

Demonstrating clinical and radiological variability of adult-onset Alexander disease in three siblings.

Three siblings in their fifth and sixth decades presented with adult-onset Alexander disease, characterized by insidious onset of motor, cerebellar, and autonomic dysfunction.

J Neurol SciJul 22, 2026Read case
Clinical ResearchPediatrics

The mirror neuron system in typically and atypically developing children: Evolution, dysfunction and rehabilitative purpose. A systematic review.

This systematic review examines the development and dysfunction of the Mirror Neuron System (MNS) in typically and atypically developing children.

Neurosci Biobehav RevJul 22, 2026Read summary
Clinical ResearchNeurology

Cerebral hemodynamic changes at high altitude in adults: a systematic review and meta-analysis of transcranial Doppler and duplex ultrasound studies.

This systematic review and meta-analysis evaluated cerebral hemodynamic changes in adults exposed to altitudes of 1,500 m or higher.

J Appl Physiol (1985)Jul 22, 2026Read summary
Clinical ResearchNeurology

Tenecteplase Efficacy in Patients With Distal Occlusions: Secondary Analysis of the TASTE Randomized Clinical Trial.

This secondary analysis of the TASTE randomized clinical trial evaluated the efficacy of tenecteplase versus alteplase in patients with distal occlusions, specifically those involving M3 and beyond, anterior, and…

StrokeJul 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Dyadic Capability in Stroke Survivors and Their Caregivers: A Systematic Review and Integrated Concept Analysis.

This systematic review and integrated concept analysis examined capability and related constructs in stroke survivors and their caregivers, with the aim of clarifying capability at the dyad level.

J Cardiovasc NursJul 22, 2026Read summary
Clinical ResearchAnesthesiology

Effects of permissive hypercapnia on intraoperative cerebral oxygenation and early postoperative cognitive function in older patients with fragile brain function during the non-acute phase undergoing laparoscopic colorectal surgery: A randomized controlled trial.

This randomized controlled trial investigated the effects of permissive hypercapnia (PHC) on cerebral oxygenation and cognitive function in 76 older patients with fragile brain function undergoing laparoscopic…

Exp GerontolJul 21, 2026Read summary
Clinical ResearchNeurology

Long-term safety and efficacy of ponesimod, an oral S1P1 receptor modulator, in relapsing-remitting multiple sclerosis (RRMS): Results from randomized phase 2b core and extension studies spanning up to 13 years.

This study evaluated the long-term safety and efficacy of ponesimod in patients with relapsing-remitting multiple sclerosis (RRMS) over a period of up to 13 years, utilizing data from a randomized phase 2b trial and its…

Mult Scler Relat DisordJul 21, 2026Read summary
Clinical ResearchNeurologyOpen access

Structural Neuroimaging Alterations in Primary Burning Mouth Syndrome: A Seed-Based d Mapping (SDM-PSI) Meta-Analysis.

This meta-analysis examined structural neuroimaging alterations in 59 patients with primary burning mouth syndrome (pBMS) compared to 63 healthy controls.

Int Dent JJul 21, 2026Read summary
Clinical ResearchNeurology

Comparative efficacy and safety of seven stem cell therapies for ischemic stroke: an updated network meta-analysis.

This network meta-analysis evaluated the efficacy and safety of seven stem cell therapies for ischemic stroke in 1,006 patients across 18 randomized controlled trials.

NeuroscienceJul 21, 2026Read summary
Clinical ResearchOncology (Medical)

Prognostic utility of tumor grade and IDH-mutation status for immunotherapy response in high grade glioma: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic value of tumor grade and IDH-mutation status in high-grade gliomas treated with immunotherapy.

J Clin NeurosciJul 20, 2026Read summary
Clinical ResearchNeurologyOpen access

Akkermansia muciniphila enhances washed microbiota transplantation in the treatment of epilepsy.

This prospective, single-center cohort study evaluated the efficacy and safety of washed microbiota transplantation (WMT) in 21 patients with epilepsy, primarily those with refractory cases.

Chin Med J (Engl)Jul 20, 2026Read summary
Clinical ResearchNeurology

Venous Sinus Stenting for Pulsatile Tinnitus: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy of venous sinus stenting (VSS) for treating pulsatile tinnitus (PT) in 850 patients, including those with idiopathic intracranial hypertension (IIH).

Otol NeurotolJul 20, 2026Read summary
Case ReportInternal Medicine (General)

The Challenges of Compassion Bias in Clinical Decision-Making: A Case-Based Ethical Analysis.

A young woman with advanced neurologic decline due to HIV-associated progressive multifocal leukoencephalopathy had artificial enteral nutrition initially deferred by clinicians.

J Pain Symptom ManageJul 20, 2026Read case
Clinical ResearchNeurologyOpen access

A systematic review of neuroimaging studies of adults aged 35 and older with clinical, symptomatic and genetic risk for attention-deficit/hyperactivity disorder.

This systematic review examined neuroimaging studies of adults aged 35 and older with clinical, symptomatic, or genetic risk for ADHD.

Dialogues Clin NeurosciJul 19, 2026Read summary
Clinical ResearchNeurology

Intra-arterial thrombolytics after endovascular thrombectomy for acute ischemic stroke: A network meta-analysis of RCTs.

This network meta-analysis evaluated the efficacy and safety of intra-arterial thrombolysis (IAT) after endovascular thrombectomy (EVT) for acute ischemic stroke in 2564 patients across eight randomized controlled…

J Neurol SciJul 19, 2026Read summary
Case ReportMedical Genetics

Novel splice-site and recurrent p.Arg729* CNKSR2 variants in ESES/CSWS: insights into sex-dependent expression.

This report describes two patients with de novo CNKSR2 variants. A 17-year-old female presented with a novel splice-site variant and a relatively mild phenotype, while an 8-year-old male exhibited a recurrent nonsense…

SeizureJul 19, 2026Read case
Case ReportMedical GeneticsOpen access

Strømme syndrome: the clinical and molecular spectrum associated with variants in CENPF.

Strømme syndrome (MIM 243605) or a form of syndromic microcephaly have both been reported to be caused by biallelic variants in CENPF.

Eur J Hum GenetJul 18, 2026Read case
Clinical ResearchNeurologyOpen access

Double-Negative Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined double-negative neuromyelitis optica spectrum disorder (DN-NMOSD) in 671 patients, comparing it to AQP4-NMOSD and MOGAD.

Neurol Neuroimmunol NeuroinflammJul 17, 2026Read summary

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