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1018 articles
June 202624
Sterile abscesses during GnRH agonist therapy for central precocious puberty: a case series and literature review.
Two patients undergoing long-acting GnRH agonist therapy for central precocious puberty developed recurrent sterile abscesses at injection sites, leading to pain and reduced treatment efficacy.
Neonatal diabetes due to a truncating RFX6 mutation in an extremely low birth weight preterm infant with Mitchell-Riley syndrome.
A preterm male infant, born at 31 weeks with a birth weight of 880 g, presented with duodenal atresia and severe hyperglycemia starting on postnatal day 4.
A phase 3, randomized study to evaluate the safety, tolerability, and immunogenicity of V116 in children and adolescents with increased risk of pneumococcal disease (STRIDE-13).
This phase 3 randomized controlled trial assessed the safety and immunogenicity of the 21-valent pneumococcal conjugate vaccine V116 in children and adolescents aged 2 to <18 years with chronic medical conditions.
The Effects of Postpartum Foot Massage on Maternal Breastfeeding Success, Sleep Quality, and Newborn Stress: A Randomized Controlled Trial.
This randomized controlled trial evaluated the impact of postpartum foot massage on breastfeeding success, sleep quality, and newborn stress in 70 primiparous women.
Systematic Review and Pooled Analysis of 1,021 Children With Pancreatic Tumors.
This systematic review analyzed 1,021 children with pancreatic tumors, revealing that solid pseudopapillary neoplasm (SPN) was the most common histology (70.4%).
Survival Following Paralytic Rabies Encephalomyelitis in a Toddler: Challenges in Confirmation of Diagnosis.
A 2-year-old toddler presented with rapidly progressive quadriparesis following a dog bite. The atypical presentation of paralytic rabies posed significant diagnostic challenges, complicated by recent post-exposure…
Three cases of hereditary hypomagnesemia with secondary hypocalcemia caused by novel TRPM6 gene mutations and a literature review.
Three Chinese children presented with afebrile convulsions, with one also experiencing gross hematuria. Genetic testing revealed four novel mutations in the TRPM6 gene.
The Pediatric Cardiac Extubation Readiness Framework: An Evidence-Derived Translational Framework for Structured Extubation Assessment Following Pediatric Cardiac Surgery.
This article presents the Pediatric Cardiac Extubation Readiness Framework (PCERF), developed through a systematic review and meta-analysis of pediatric cardiac surgical populations.
Unmanipulated Haploidentical Stem Cell Transplantation Outcome in a Pediatric Patient With CD27 Deficiency and EBV-Induced Diffuse Large B-Cell Lymphoma With Primary CNS Involvement.
A pediatric patient with CD27 deficiency developed EBV-associated diffuse large B-cell lymphoma with primary CNS involvement and experienced an early relapse.
Clinical accuracy and applications of large language models in pediatric orthopedics: a systematic review.
This systematic review evaluated the accuracy and clinical applicability of large language models (LLMs) in pediatric orthopedics, analyzing 15 studies.
The Impact of Massage on Pain and Vital Signs Following Cardiovascular Surgery in Pediatric Patients.
This randomized controlled study assessed classical massage for postoperative pain and vital signs in 86 children recovering from cardiovascular surgery.
Deep brain stimulation of the nucleus accumbens for severe self-injurious behaviour in children: long-term outcomes from a first-in-human pilot trial.
This prospective, single-centre, first-in-human clinical trial assessed bilateral nucleus accumbens deep brain stimulation in six children and adolescents aged 7–14 years with profound autism and treatment-refractory…
Transparent Film Dressing Versus Microporous Paper Tape for Temperature Probe Fixation in Preterm Neonates: A Randomized Controlled Trial.
This randomized controlled trial compared transparent film dressing with microporous paper tape for securing temperature probes in preterm neonates receiving radiant warmer care.
Isolated Paroxysmal Right Upward Eye Deviation as the Sole Semiology of Childhood Occipital Epilepsy: An Electroclinical Case Report.
A 6-year-old boy presented with frequent daily episodes of isolated right upward eye deviation, lacking other ictal features such as impaired awareness or visual symptoms.
A child and young person focused systematic review of scrotal ultrasound with Mitigants to identify missed torsion.
This systematic review and meta-analysis evaluated the diagnostic accuracy of ultrasound for testicular torsion in children and young people (CYP).
Effectiveness of Social Robots in Relieving Children's and Adolescents' Anxiety, Pain, Fear and Stress in Perioperative Nursing: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of social robots in alleviating anxiety, pain, fear, and stress in children and adolescents undergoing perioperative care.
Evaluating the impact of diverse essential newborn care training modalities for fathers on self-efficacy and father-infant attachment: A randomized clinical trial.
This randomized controlled trial evaluated the impact of different essential newborn care training modalities on paternal self-efficacy and father-infant attachment among first-time fathers.
Transcranial Alternating Current Stimulation at 40 Hz Improves Social Functioning in Children With Autism Spectrum Disorder: A Randomized Clinical Trial.
This randomized controlled trial investigated the effects of 40-Hz transcranial alternating current stimulation (tACS) on social functioning in 47 children with autism spectrum disorder (ASD).
Assessment of postoperative outcomes of LAT-HSL in the treatment of unilateral inguinal hernia in boys: A multicenter prospective randomized controlled study.
This multicenter prospective randomized controlled trial compared laparoscope-assisted trans-scrotal hernia sac ligation (LAT-HSL) and laparoscopic hernia needle extraperitoneal high ligation (LH) in boys aged 1-3 years…
Case Study on the Use of Real-World Evidence in a Feasibility Assessment of a Randomized Controlled Trial Design to Support the Fulfillment of Pediatric Requirements with the FDA and EMA.
This study assessed the feasibility of a randomized controlled trial (RCT) for denosumab in pediatric patients with glucocorticoid-induced osteoporosis (GiOP).
Fraction-dependent dose dynamics and clinical safety in high-risk neuroblastoma treated with [ 177 Lu]Lu-DOTATATE: results from the LuDO-N trial.
The LuDO-N trial evaluated the safety and dosimetry of a two-fraction regimen of [177Lu]Lu-DOTATATE in 14 patients with high-risk neuroblastoma.
Delayed-interval delivery in a trichorionic triamniotic triplet pregnancy: Prolongation of pregnancy after premature delivery of two fetuses, a case report.
A 31-year-old woman with a trichorionic triamniotic triplet pregnancy delivered two fetuses prematurely at 22 + 3 and 22 + 5 weeks.
A scaffold-degradable single-rivet ASD occluder with amplatzer-like design: a multicenter randomized controlled trial.
This multicenter randomized controlled trial evaluated the safety and efficacy of a biodegradable Pansy ASD occluder in 112 patients, including 71 pediatric cases.
Comparison of computer-controlled intraosseous anaesthesia and conventional anaesthesia in paediatric dentistry: a split-mouth randomised clinical trial.
This randomized clinical trial compared the efficacy and patient acceptance of Computer-Controlled Intraosseous Anaesthesia (CCIA) and Conventional Local Anaesthesia (CLA) in 64 healthy children aged 5-9 years.
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