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947 articles

October 202624

Clinical ResearchCardiologyOpen access

Integrated management of atrial fibrillation with digital health support: a pooled analysis of individual participant data from the mAFA-II and MIRACLE-AF trials.

This pooled individual participant data analysis combined two prospective randomised trials of adults with atrial fibrillation: mAFA-II, which delivered ABC pathway care through a mobile app, and MIRACLE-AF, which used…

Cardiovasc ResOct 10, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Assisted Reproductive Technology and Risk of Congenital Heart Defects in the Offspring: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed congenital heart defect (CHD) risk in offspring conceived through assisted reproductive technology (ART) compared with spontaneous conception.

J Am Heart AssocOct 10, 2026Read summary
Clinical ResearchCardiology

Body Mass Index, Valsartan, and Myocardial Remodeling in Early-Stage Hypertrophic Cardiomyopathy: A Secondary Analysis of the Randomized VANISH Trial.

This post hoc analysis of the randomized, multicenter VANISH trial examined BMI and cardiac remodeling in participants with early-stage hypertrophic cardiomyopathy. Of 171 participants, 52% had elevated BMI.

J Am Heart AssocOct 10, 2026Read summary
Clinical ResearchCardiology

Pilot Randomized Trial of 2 Food Purchasing Interventions in Individuals With Hypertension in New Orleans: An American Heart Association Food Is Medicine Initiative.

This randomized pilot trial compared online and in-store food vouchers among 98 people with uncontrolled hypertension in New Orleans.

J Am Heart AssocOct 10, 2026Read summary
Clinical ResearchVascular Surgery

Omega-6 Polyunsaturated Fatty Acids and Peripheral Artery Disease: An Individual Participant-Level Analysis of 9 International Prospective Studies.

This multicohort individual participant-level analysis and meta-analysis examined baseline omega-6 polyunsaturated fatty acids and incident peripheral artery disease (PAD) among 137,704 participants without clinical PAD…

J Am Heart AssocOct 10, 2026Read summary
Case ReportCardiology

Balanced double aortic arch with late-onset symptoms detected on 18F-FDG PET/CT in an octogenarian with advanced prostate cancer: A case report.

An 80-year-old man with advanced prostate cancer underwent 18F-FDG PET/CT for staging. He reported dysuria and back pain for more than a year, with mild intermittent swallowing discomfort.

Medicine (Baltimore)Oct 9, 2026Read case
Case ReportPulmonology

Kartagener syndrome with pulmonary mycetoma and recurrent thromboembolism: A case report.

A 27-year-old man with Kartagener syndrome and situs inversus totalis presented with worsening dyspnea, chest pain, fever, hemoptysis, and ankle swelling, against a history of deep vein thrombosis, recurrent pulmonary…

Medicine (Baltimore)Oct 9, 2026Read case
Case ReportCardiology

ST elevation in lead aVR - a marker of critical left main coronary artery stenosis: A series of case reports and literature review.

Five consecutive patients presenting with acute chest pain or cardiac arrest had ST-segment elevation of at least 1 mm in lead aVR with diffuse ST depression of at least 1 mm in six or more leads.

Medicine (Baltimore)Oct 9, 2026Read case
Case ReportCardiologyOpen access

Axillary microaxial flow pump support for stepwise source control and bridge to durable left ventricular assist device therapy in cardiac device-related infective endocarditis.

A 53-year-old man with long-standing dilated cardiomyopathy presented with cardiac resynchronization therapy-defibrillator infection, methicillin-sensitive Staphylococcus aureus bacteremia, respiratory failure, acute…

J Artif OrgansOct 9, 2026Read case
Clinical ResearchOncology (Medical)

Attributable fraction of cardiac disease following radiotherapy among breast cancer survivors: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed the relationship between mean heart dose (MHD) from radiotherapy and cardiac disease among breast cancer survivors.

J Radiat ResOct 9, 2026Read summary
Clinical ResearchCardiology

Blinded withdrawal of randomized treatment with low-dose digoxin or placebo in heart failure: the DECISION trial.

This pre-specified analysis of the multicentre, randomised DECISION trial examined blinded withdrawal of long-term low-dose digoxin or placebo in patients with heart failure and reduced or mildly reduced ejection…

Eur Heart JOct 9, 2026Read summary
Clinical ResearchCardiology

Sex differences in pharmacological treatment of heart failure: a meta-analysis of randomized trials.

This systematic review and meta-analysis examined sex differences in pharmacological treatment effects across randomized heart failure trials and whether women’s representation influenced estimated efficacy.

Eur Heart JOct 9, 2026Read summary
Case ReportCardiologyOpen access

Extracorporeal Cardiopulmonary Resuscitation as a Bridge to Cardiac Transplantation in Refractory Cardiac Arrest Due to Fulminant Myocarditis: A Case Report.

A previously healthy 36-year-old woman presented with fulminant myocarditis and cardiogenic shock, then sustained an in-hospital cardiac arrest that did not respond to conventional CPR.

Int Med Case Rep JOct 9, 2026Read case
Clinical ResearchCardiologyOpen access

Efficacy and safety of PCSK9 inhibitors combined with statins in acute ischemic stroke: a systematic review and meta-analysis.

This systematic review and meta-analysis of randomized controlled trials compared PCSK9 inhibitors plus statins with statins alone in patients with acute ischemic stroke.

J NeurolOct 8, 2026Read summary
Case ReportCardiologyOpen access

Advanced Rheumatic Heart Disease Complicated by Pregnancy, Mitral Valve Disease, Pulmonary Hypertension, and Left Atrial Thrombus: A Multidisciplinary Case Report from Resource-Limited Settings.

A 27-year-old woman in late pregnancy presented with progressive dyspnea, palpitations, leg swelling, cough, and fatigue. Echocardiography showed an enlarged left atrium, moderate mitral stenosis with mild regurgitation…

Int Med Case Rep JOct 8, 2026Read case
Case ReportPlastic Surgery

Capsulectomy at Explant: Rethinking Spinal Cord Stimulator Infected Generator Pocket Management in the Immunocompromised-A Case Series.

Two immunocompromised women with spinal cord stimulator (SCS) infections underwent explantation and capsulectomy. The first patient, with ulcerative colitis and psoriatic arthritis, developed granulation tissue and was…

Pain PractOct 7, 2026Read case
Clinical ResearchEndocrinologyOpen access

Disparities in GLP-1RA and SGLT2i Uptake: a Systematic Review and an Equity-First Framework for Cardiovascular-Kidney-Metabolic Care.

This systematic review synthesised U.S. evidence on disparities in prescribing and initiation of GLP-1 receptor agonists and SGLT2 inhibitors, and proposed an equity-first framework for cardiovascular-kidney-metabolic…

Curr Cardiol RepOct 7, 2026Read summary
Clinical ResearchCardiology

EACTS Expert Consensus Document on aortic valve repair and valve-sparing aortic root replacement procedures.

This EACTS Expert Consensus Document critically reviews evidence on aortic valve repair and valve-sparing aortic root replacement for aortic regurgitation and proximal thoracic aortic aneurysms across age groups.

Eur J Cardiothorac SurgOct 7, 2026Read summary
Clinical ResearchCardiology

Acute effects of volume-matched isometric exercise intensity on vascular function and autonomic regulation in men with elevated blood pressure.

This randomized controlled trial examined the acute effects of high-intensity isometric exercise (HIIE) versus low-intensity isometric exercise (LIIE) on cardiovascular function in 17 men with elevated blood pressure.

Clin Physiol Funct ImagingOct 6, 2026Read summary
Clinical ResearchCardiologyOpen access

Comparative efficacy and safety of orally administered PCSK9 inhibitors in patients with Hypercholesterolaemia: a dose-stratified systematic review and network meta-analysis.

This network meta-analysis evaluated the efficacy and safety of orally administered PCSK9 inhibitors in patients with hypercholesterolemia, analyzing five randomized trials with 4,227 participants.

EndocrineOct 6, 2026Read summary
Clinical ResearchCardiologyOpen access

Ventriculo-arterial coupling in acute heart failure: prognostic and therapeutic insights - a systematic review and meta-analysis of multivariable-adjusted data.

This systematic review and meta-analysis evaluated the prognostic significance of non-invasive ventricular-arterial coupling (VAC) in 36,989 patients hospitalized with acute heart failure (AHF).

Heart Fail RevOct 6, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Cardiovascular safety in middle-aged and older men under testosterone replacement therapy: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the cardiovascular safety of testosterone replacement therapy (TRT) in middle-aged and older men, analyzing data from 31 randomized-controlled trials involving 9,437…

EndocrineOct 6, 2026Read summary
Clinical ResearchCardiothoracic Surgery

Minimally Invasive Versus Sternotomy in Redo Mitral Valve Surgery: Short- and Long-Term Outcomes with Meta-Regression and Time-to-Event Analysis.

This meta-analysis compared minimally invasive mitral valve surgery (MI-MVS) with sternotomy for redo surgery in adults. It included 15 studies and 3457 patients, pooling perioperative outcomes and reconstructing…

J Am Heart AssocOct 6, 2026Read summary
Case ReportPediatricsOpen access

Rupture of Left Ventricular Aneurysm in Infant: Case Report.

A preterm infant hospitalized from birth with necrotizing enterocolitis, later complicated by ascending-colon narrowing requiring surgery, had persistent infections with Staphylococcus haemolyticus and then…

Int Med Case Rep JOct 6, 2026Read case

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