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751 articles
October 202624
Values, preferences, and treatment burden for initiation of GLP-1 receptor agonists, SGLT-2 inhibitors, tirzepatide, and finerenone in adults with type 2 diabetes: systematic review.
This systematic review synthesised quantitative and qualitative evidence on treatment values, preferences, and perceived burden among adults with type 2 diabetes considering GLP-1 receptor agonists, SGLT-2 inhibitors…
Emerging risks of health optimisation: refractory nausea associated with peptide injections reported to contain retatrutide.
A woman in her mid-20s presented with five days of persistent nausea, repeated vomiting, loose stools and markedly reduced oral intake.
Facial nerve palsy and hypertension; unusual presentation of apparent mineralocorticoid excess (AME) syndrome in a paediatric patient.
A boy in early childhood presented after two days of right-sided facial palsy and was found to have severe hypertension with end-organ damage.
Disparities in GLP-1RA and SGLT2i Uptake: a Systematic Review and an Equity-First Framework for Cardiovascular-Kidney-Metabolic Care.
This systematic review synthesised U.S. evidence on disparities in prescribing and initiation of GLP-1 receptor agonists and SGLT2 inhibitors, and proposed an equity-first framework for cardiovascular-kidney-metabolic…
Betaine supplementation modulates mitochondrial and redox-related adaptations in premenopausal women with overweight: a randomized controlled trial.
This randomized controlled trial examined whether eight weeks of betaine supplementation (3 g/d) affected mitochondrial-associated and redox measures in premenopausal women with overweight or obesity.
GLP-1 receptor agonists for obstructive sleep apnea: a meta-analysis of randomized controlled trials.
This meta-analysis of randomized controlled trials evaluated the efficacy and safety of GLP-1 receptor agonists in adults with moderate-to-severe obstructive sleep apnea (OSA).
Cardiovascular safety in middle-aged and older men under testosterone replacement therapy: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the cardiovascular safety of testosterone replacement therapy (TRT) in middle-aged and older men, analyzing data from 31 randomized-controlled trials involving 9,437…
Genome-wide meta-analysis dissects the genetic basis and health implications of circulating taurine.
This genome-wide meta-analysis examined the genetic basis of circulating taurine levels in 36,490 European individuals. The study identified six common and two rare genetic loci associated with taurine levels and…
Severe Euglycemic Diabetic Ketoacidosis After Semaglutide-Associated Poor Intake Despite Empagliflozin Discontinuation: A Case Report.
A 68-year-old woman with long-standing type 2 diabetes developed several weeks of nausea, intermittent vomiting and diarrhea, and minimal oral intake after starting semaglutide.
Refractory amiodarone-induced thyrotoxicosis causing malignant arrhythmias, treated with therapeutic plasma exchange-bridged thyroidectomy.
A man in his mid-60s with severe cardiomyopathy developed refractory amiodarone-induced thyrotoxicosis, leading to recurrent ventricular tachycardia.
Myxoedema coma in a patient with alcohol dependence: a diagnostic pitfall.
A man in his sixties with known hypothyroidism and alcohol dependence presented with profound hypothermia, refractory hypoglycaemia, hypoxia, and reduced consciousness.
Iatrogenic Cushing's syndrome from an adulterated glucocorticoid-containing supplement.
A man in his 40s presented with rapid weight gain, fatigue, and signs of Cushing's syndrome, including abdominal striae and centripetal obesity.
Cardiovascular Morbidity and Mortality in Chronic Hypoparathyroidism: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the cardiovascular risks associated with chronic hypoparathyroidism (HypoPT) in adults.
Effects of rosehip (Rosa canina) supplementation on orthostatic intolerance symptoms in patients with type 2 diabetes: a randomized double-blind placebo-controlled clinical trial.
This randomized double-blind placebo-controlled trial investigated the effects of rosehip fruit extract on orthostatic intolerance symptoms in 60 adults with type 2 diabetes and orthostatic hypotension.
Chestnut flour-enriched bread reduces postprandial glycaemic response in healthy adults: a randomised, controlled crossover study.
This randomized controlled crossover study evaluated the impact of chestnut flour-enriched bread on postprandial glycaemic responses in fourteen healthy adults.
Off-label palopegteriparatide for severe pediatric postsurgical hypocalcemia.
A 14-year-old boy with Graves’ disease developed profound hypocalcemia after total thyroidectomy, with serum calcium 5.9 mg/dL, ionized calcium 0.83 mmol/L, and undetectable parathyroid hormone.
Interference of iron deficiency in glycated hemoglobin testing and its clinical implications: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of iron deficiency anemia (IDA) and latent iron deficiency (LID) on glycated hemoglobin (HbA1c) concentrations.
Bone Anabolic Treatment in Patients With Chronic Kidney Disease: A Systematic Review.
This systematic review evaluated the efficacy and safety of anabolic parathyroid hormone (PTH) treatments in patients with chronic kidney disease (CKD) Stages 4-5D.
Effects of SGLT-2 Inhibitors on Plasma Concentrations and Renal Clearance of the Risk Marker Trimethylamine-N-Oxide in Patients With Type-2 Diabetes.
This randomized controlled trial investigated the effects of SGLT-2 inhibitors empagliflozin and dapagliflozin on plasma levels and renal clearance of trimethylamine-N-oxide (TMAO) in patients with Type 2 diabetes.
Androgen insensitivity syndrome: A case report.
A 29-year-old phenotypic female presented with primary amenorrhea and intermittent abdominal pain. Examination revealed normal breast development, sparse pubic hair, and female external genitalia.
Serum 25-hydroxyvitamin D levels are associated with thyroid diseases: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the relationship between serum 25-hydroxyvitamin D levels and thyroid diseases, including autoimmune thyroid diseases (AITDs).
Renoprotective effects and safety of sodium-glucose cotransporter 2 inhibitors in diabetic chronic kidney disease: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on patients with diabetic chronic kidney disease (CKD).
Prevalence of metabolic syndrome among patients with Alzheimer disease: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence of metabolic syndrome (MetS) in patients with Alzheimer disease (AD).
Therapeutic value of continuous subcutaneous insulin infusion with electrolyte supplementation for pediatric diabetic ketoacidosis.
This randomized controlled trial evaluated the efficacy and safety of continuous subcutaneous insulin infusion (CSII) with electrolyte supplementation in 66 pediatric patients with diabetic ketoacidosis (DKA).
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