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793 articles
March 20264
Efficacy of NAs in combination with Peg-IFN for functional cure in patients with CHB: a meta-analysis of RCTs.
This meta-analysis of 16 randomised controlled trials assessed nucleoside (acid) analogues (NAs) combined with pegylated interferon (Peg-IFN) for functional cure in people with chronic hepatitis B.
Upfront endoscopic necrosectomy versus step-up endoscopic approach for walled-off pancreatic necrosis: a systematic review and meta-analysis.
This systematic review and meta-analysis compared upfront endoscopic necrosectomy (UEN) with a step-up endoscopic approach (SUEN) for walled-off pancreatic necrosis.
Efficacy and safety of endoscopic ultrasound-guided choledochoduodenostomy compared with endoscopic ultrasound-guided gallbladder drainage for palliation of malignant distal biliary obstruction: a systematic review and meta-analysis.
This systematic review and meta-analysis compared endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) with gallbladder drainage (EUS-GBD) for palliation of malignant distal biliary obstruction when ERCP is not…
A Transfusion-transmitted Chronic Hepatitis E Virus Infection after Allogeneic Bone Marrow Transplantation with Viral Clearance Following Immunosuppression Tapering.
A 62-year-old woman with myelofibrosis developed liver dysfunction after allogeneic bone marrow transplantation. Testing showed anti-HEV IgA and HEV RNA, and matching viral RNA sequences in the transfusion donor and…
February 202620
Long-Term Safety of Upadacitinib in Patients With Inflammatory Bowel Disease: Integrated Analysis of Phase 2/3 Studies.
This integrated safety analysis pooled six phase 2/3 trials of upadacitinib in patients with ulcerative colitis or Crohn’s disease.
Gastric fundal mucosal ablation followed by endoscopic sleeve gastroplasty in adults with obesity: a first-in-human two-phase pilot clinical trial.
This prospective, first-in-human, two-phase pilot clinical trial evaluated sequential gastric fundal mucosal ablation (GFMA) followed by endoscopic sleeve gastroplasty (ESG) in 10 adults with obesity.
Vagal Nerve Stimulation for Chronic Constipation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and random-effects meta-analysis of six randomized controlled trials assessed transcutaneous auricular vagus nerve stimulation and transcutaneous electroacupuncture for chronic constipation.
Efficacy and safety of split-dose ultra-low-volume polyethylene glycol with ascorbic acid versus sodium picosulfate with magnesium citrate for bowel preparation: a systematic review and meta-analysis.
This systematic review and meta-analysis compared split-dose ultra-low-volume polyethylene glycol with ascorbic acid (PEG + Asc) against sodium picosulfate with magnesium citrate for colonoscopy bowel preparation.
Hepatocellular Carcinoma Associated with Hepatic Sarcoidosis and Budd-Chiari Syndrome: A Case Report and Review of the Literature.
A 71-year-old woman with cutaneous sarcoidosis presented with hepatocellular carcinoma. Evaluation identified Budd-Chiari syndrome, indicating hepatic venous outflow obstruction, and hepatic granulomas with advanced…
An Effective Case of Radiofrequency Ablation with the Combination of Durvalumab and Tremelimumab Treatment for Hepatocellular Carcinoma.
A 77-year-old man with advanced hepatocellular carcinoma received durvalumab plus tremelimumab. Imaging showed tumor shrinkage and serum tumor markers normalized, but contrast-enhanced ultrasound detected residual…
Glucocorticoid Therapy and Miglitol Ameliorate Reactive Hypoglycemia Secondary to Late Dumping Syndrome.
A 73-year-old man developed symptomatic reactive hypoglycemia attributed to late dumping syndrome after esophagectomy with gastric tube reconstruction.
Phlegmonous Gastritis in Chemotherapy-related Neutropenia with Endoscopic Findings that Prompted Early Therapeutic Intervention.
A 56-year-old man with chemotherapy-related neutropenia and immunosuppression presented with shock and epigastric pain. CT showed diffuse gastric wall thickening, while endoscopy demonstrated extensive mucosal injury…
Artificial intelligence for the prediction of synchronous and metachronous liver metastasis in colorectal cancer patients: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed imaging-based artificial intelligence models for predicting synchronous and metachronous liver metastases in patients with colorectal cancer.
Transanal irrigation for low anterior resection syndrome: a systematic review and narrative synthesis with emphasis on nurse-led implementation.
This systematic review and narrative synthesis examined transanal irrigation (TAI) for adults with low anterior resection syndrome after sphincter-preserving rectal surgery, including evidence on nurse-led…
Familial Mediterranean Fever Presenting with Recurrent Abdominal Pain without Periodic Fever Following COVID-19.
A 16-year-old girl developed recurrent abdominal pain without fever after COVID-19. Initial evaluation, including endoscopy, was unremarkable apart from mildly elevated fecal calprotectin (182.1 μg/g).
Hepatic Encephalopathy is the Key Driver of Symptom Burden in a Longitudinal Cohort of Patients With Advanced Chronic Liver Disease: PAL-LIVER Substudy.
This secondary analysis of the 19-site PAL-LIVER cluster-randomized trial examined symptom and caregiver-burden trajectories among patients with decompensated cirrhosis and/or hepatocellular carcinoma.
Antibiotic Use Linked to Worse Outcomes in Patients With Gastrointestinal and Liver Cancer on Immune Checkpoint Inhibitors: A Meta-Analysis.
This meta-analysis assessed whether antibiotic use was associated with outcomes in adults with gastrointestinal or liver cancers receiving immune checkpoint inhibitors.
Fatal Fungal Peritonitis Caused by Aspergillus udagawae: An Autopsy Case Report.
A 56-year-old man with chronic progressive pulmonary aspergillosis caused by multidrug-resistant Aspergillus udagawae developed acute abdominal pain.
Diverticular Perforation with Normal C-reactive Protein in a Patient with Neuromyelitis Optica Spectrum Disorder Receiving Satralizumab.
A 49-year-old woman with neuromyelitis optica spectrum disorder receiving satralizumab developed mild abdominal pain. Although C-reactive protein had risen transiently earlier in her hospitalization, it was normal when…
Endoscopic Submucosal Dissection as a Diagnostic and Minimally Invasive Therapeutic Excision Modality for Primary Anorectal Malignant Melanoma.
An 82-year-old man with primary anorectal malignant melanoma underwent endoscopic submucosal dissection (ESD), which served as a total biopsy and minimally invasive excision.
Biodegradable Stents in Benign Biliary and Pancreatic Disease: A Systematic Review.
This systematic review assessed human studies of biodegradable stents for benign biliary and pancreatic diseases, including strictures and bile leaks.
Clinical Utility of a 50% and 30% Decline in Magnetic Resonance Imaging-Proton Density Fat Fraction in Predicting Fibrosis Improvement in Metabolic Dysfunction-Associated Steatohepatitis.
This secondary analysis of a multicentre, randomised, placebo-controlled trial assessed whether MRI-PDFF declines predict histological improvement in 163 participants with biopsy-confirmed MASH and stage 2 or 3 fibrosis…
Fecal incontinence after prostate cancer irradiation: a systematic literature review.
This systematic review synthesized evidence on fecal incontinence (FI) after definitive or adjuvant/salvage radiotherapy for prostate cancer, including 54 articles identified through a PRISMA-guided search.
Infliximab and Upadacitinib Demonstrate Superior Early Onset of Efficacy in Biologic-Naïve Ulcerative Colitis With Severe Endoscopic Disease.
This post hoc analysis pooled individual participant-level data from 11 randomized controlled trials to compare onset and induction efficacy of advanced therapies in biologic-naïve patients with ulcerative colitis and…
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