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1018 articles
May 202624
The first neonatal case of Juvenile Paget disease with homozygous deletion in the TNFRSF11B gene.
A male newborn, born at 31 1/7 weeks gestation, presented with respiratory distress and varus deformity of the lower extremities. Radiographic findings revealed diffuse osteosclerosis in long bones.
Vascular and Wound-Healing Implications of Single-Stage Versus Multistage Repair of Anorectal Malformations: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated wound-related complications and long-term functional outcomes of single-stage versus multistage repair of anorectal malformations (ARMs) in neonates and infants.
Focal False-Positive 18 F-MFBG Uptake in the Kidney Attributable to Renal Infarction in a Pediatric Patient With Pheochromocytoma.
A 10-year-old boy presented for 18 F-MFBG PET/CT imaging to evaluate a right adrenal lesion. The imaging showed moderate uptake in the lesion and unexpected focal uptake in the lower pole of the right kidney.
Randomized Clinical Trial Comparing Effects of Pulsatile vs Nonpulsatile Cardiopulmonary Bypass on Neurologic Outcomes.
This randomized controlled trial evaluated the effects of pulsatile versus nonpulsatile cardiopulmonary bypass on S100B levels and neurological outcomes in pediatric patients undergoing congenital heart surgery.
Safety and Immunogenicity of Varicella Vaccination in Children and Adolescents Living With HIV: A Systematic Review.
This systematic review evaluated the safety and immunogenicity of varicella vaccination in HIV-positive children. Analyzing 18 studies, it found that local reactions occurred in less than 21% of vaccinees after the…
Long-Term Outcomes of Balloon Versus Surgical Aortic Valvuloplasty in Pediatric Patients with Congenital Aortic Valve Stenosis: A Meta-Analysis.
This meta-analysis evaluated long-term outcomes of balloon aortic valvuloplasty (BAV) versus surgical aortic valvuloplasty (SAV) in 1704 pediatric patients with congenital aortic valve stenosis.
Letrozole Treatment in Idiopathic Peripheral Precocious Puberty Without Diagnosis of McCune-Albright Syndrome: A Case Report.
A girl with idiopathic peripheral precocious puberty presented with premature thelarche, recurrent vaginal bleeding, and elevated estradiol levels, alongside ultrasound findings of ovarian cysts.
Systemic lupus erythematosus with lupus nephritis in a child with chronic granulomatous disease: a diagnostic and therapeutic challenge.
An 11-year-old boy with X-linked chronic granulomatous disease presented with systemic lupus erythematosus and class IV/V lupus nephritis.
Could the grafted Snodgrass technique be a standard approach for repair of distal hypospadias with a narrow urethral plate? A comparative study.
This randomized comparative study at Sohag University Hospitals evaluated Snodgraft versus classic Snodgrass repair in patients with distal hypospadias and a narrow urethral plate (<8 mm).
Detection of mandibular condylar fractures on head CT scans in infants with witnessed falls.
This case series highlights infants who sustained isolated mandibular condylar fractures following witnessed falls. These fractures were initially detected through head CT scans, underscoring the challenges of clinical…
Memantine for Prevention of Cognitive Late Effects in Children and Adolescents Receiving Radiation Therapy for Brain Tumors: A Randomized, Controlled, Pilot Trial.
This randomized, double-blind, placebo-controlled pilot trial assessed the feasibility, acceptability, and preliminary efficacy of memantine for preventing cognitive late effects in children and adolescents receiving…
A systematic review of short-term outcomes in patients with anti-factor H associated atypical HUS managed with plasma exchanges versus eculizumab.
This systematic review compared short-term outcomes in patients with anti-factor H antibody-associated atypical haemolytic uraemic syndrome affecting native kidneys, treated with plasma exchange (PEX) or eculizumab…
Effectiveness of chlorhexidine gluconate-impregnated dressings in preventing central line-associated bloodstream infection in a paediatric intensive care unit: A randomised controlled trial.
This randomized controlled trial evaluated the effectiveness of chlorhexidine gluconate (CHG)-impregnated dressings in preventing central line-associated bloodstream infections (CLABSI) in 250 pediatric patients in a…
Shorter- vs. longer-course antibiotics in children with acute uncomplicated UTIs: a systematic review and meta-analyses.
This systematic review and meta-analysis evaluated the efficacy and safety of shorter-course (2-5 days) versus longer-course (≥7 days) antibiotic therapy in 2010 children with acute uncomplicated urinary tract…
Key performance indicators for acute kidney replacement therapy in critically ill children: a systematic review.
This systematic review evaluated key performance indicators (KPIs) for kidney replacement therapy (KRT) in critically ill children.
A novel mutation in glycogen storage disease type XI presenting with neonatal cholestasis and infection-triggered hepatic flares.
A male infant presented at 12 days of age with severe cholestasis and hepatomegaly, later developing hypophosphatemic rickets and proximal renal tubular dysfunction.
Neonatal hydrometrocolpos secondary to vaginal atresia causing obstructive uropathy and renal dysfunction.
A preterm female neonate had antenatal ultrasound findings of bilateral enlarged kidneys, ascites, and polyhydramnios. After birth, she developed sepsis and elevated serum creatinine.
Cochlear Implantation in Patients With CHARGE Syndrome: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated cochlear implantation (CI) outcomes in 85 patients with CHARGE syndrome across 15 studies.
Neurologic Presentations of Pediatric Intussusception Lead to Diagnostic Delay and Increased Need for Surgery.
A 2-year-old boy presented with orofacial dyskinesias and upper-extremity jerks, initially misdiagnosed as tardive dyskinesia. Despite normal neurological examination and brain MRI, he developed bilious vomiting.
Anti-glomerular basement membrane nephritis following IgA vasculitis in a child: a diagnostic challenge.
An 8-year-old girl presented with symptoms initially attributed to IgA vasculitis, but further evaluation revealed anti-glomerular basement membrane nephritis.
Daytime Versus After-hours Surgical Fixation of Pediatric Supracondylar Humeral Fractures: A Meta-analysis.
This systematic review and meta-analysis compared daytime with after-hours operative fixation of pediatric supracondylar humeral fractures. Seven comparative studies included 913 children.
Incidence of Bacille Calmette-Guérin associated lymphadenitis in healthy children: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence of Bacille Calmette-Guérin (BCG) lymphadenitis in healthy children, analyzing data from 52 studies involving approximately 1.8 million children.
Effects of three different auditory interventions on physiological and behavioral responses to neonatal heel lance.
This randomized controlled trial evaluated the effects of white noise, classical music, and mother-sung lullabies on neonatal pain responses during heel lance in 100 newborns.
Global Pediatric Stroke Epidemiology: A Systematic Review of the Literature and Meta-Analysis.
This systematic review and meta-analysis assessed the global burden of pediatric stroke, revealing a birth prevalence of perinatal stroke at 21.01 per 100,000 total births and a childhood incidence of stroke at 3.73 per…
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