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1088 articles

April 202624

Clinical ResearchGeriatrics

Efficacy of adjunctive intermittent theta-burst stimulation on depressive and insomnia symptoms in elderly patients with depression and comorbid insomnia: A randomized, sham-controlled trial.

This randomized, sham-controlled trial investigated the effects of intermittent theta-burst stimulation (iTBS) on depressive and insomnia symptoms in 36 elderly patients with late-life depression and comorbid insomnia.

J Affect DisordApr 22, 2026Read summary
Clinical ResearchPsychiatryOpen access

Target engagement in a head-to-head clinical trial of dysphoric versus anxiosomatic transcranial magnetic stimulation targets.

This randomized controlled trial investigated the effects of transcranial magnetic stimulation (TMS) on patients with depression and anxiety, comparing two targets: dorsolateral prefrontal for dysphoric symptoms and…

NeuropsychopharmacologyApr 22, 2026Read summary
Clinical ResearchPsychiatry

Digital interoceptive-enhanced exercise for young adults with depression: A randomized controlled trial.

This randomized controlled trial evaluated a digital intervention combining structured physical activity with interoceptive training in 46 young adults with mild to moderate depressive symptoms.

J Affect DisordApr 21, 2026Read summary
Clinical ResearchPsychiatryOpen access

Multimodal microglial and kynurenine pathway alterations across the affective-psychosis spectrum: a systematic review of patterns, heterogeneity, and dimensional implications.

This systematic review examined immune dysregulation in major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCZ) through microglial and kynurenine pathway alterations.

Mol PsychiatryApr 21, 2026Read summary
Clinical ResearchPsychiatryOpen access

Childhood cognitive control as a predictor of long-term clinical and functional outcomes in Tourette syndrome.

This randomized controlled trial examined the role of childhood cognitive control in predicting long-term outcomes in 80 individuals with Tourette syndrome (TS).

J Child Psychol PsychiatryApr 21, 2026Read summary
Clinical ResearchGeriatrics

Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) on depression and anxiety in older adults: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) on depressive symptoms in older adults (≥60 years).

J Behav Ther Exp PsychiatryApr 20, 2026Read summary
Case ReportPsychiatry

Breaking the Silence: Using Therapeutic Assessment to Give Voice to Shame and Trauma. A Single-Case Repeated-Measures Design.

Mei, a woman with severe PTSD, complex PTSD, and shame, underwent Therapeutic Assessment (TA). The report examined her daily self-reports before and for 25 days after the assessment, alongside pre-, mid-, and…

J Pers AssessApr 20, 2026Read case
Clinical ResearchPsychiatry

Modifying dysfunctional beliefs in social anxiety disorder with an emotion-focused approach-avoidance modification training - a pilot study.

This randomized controlled pilot study evaluated the feasibility and therapeutic potential of an emotion-focused approach-avoidance modification training (eAAMT) for social anxiety disorder (SAD) in 30 participants.

J Behav Ther Exp PsychiatryApr 19, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of high-definition transcranial direct current stimulation on craving in substance use disorders: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy of high-definition transcranial direct current stimulation (HD-tDCS) on craving in substance use disorders, analyzing three randomized controlled trials…

J Addict DisApr 18, 2026Read summary
Clinical ResearchGeriatrics

Predictors of Cognitive Behavioral Therapy for Insomnia in Older Adults.

This randomized controlled trial investigated predictors of success in Cognitive Behavioral Therapy for Insomnia (CBT-I) among 96 older adults with insomnia.

Behav Sleep MedApr 17, 2026Read summary
Clinical ResearchPsychiatry

What are the experiences of people with psychosis, their carers and staff in inpatient mental healthcare services in the United Kingdom? A systematic review and meta-ethnography.

This systematic review and meta-ethnography synthesized qualitative research on inpatient mental healthcare experiences among people with psychosis, their carers and staff in the United Kingdom.

Br J Clin PsycholApr 17, 2026Read summary
Clinical ResearchPsychiatry

Improving Sleep and PTSD Outcomes in Service Members: A Randomized Controlled Trial Examining the Long-Term Effects of an Integrated Treatment.

This randomized controlled trial compared Compressed Prolonged Exposure (CPE) with Trauma Management Therapy (TMT), which combines exposure therapy with sleep hygiene and other skills, in 82 active-duty service members…

Behav TherApr 15, 2026Read summary
Clinical ResearchPsychiatryOpen access

Accelerated intermittent theta burst stimulation targeting personalized fronto-parietal control network improves core symptoms of autism spectrum disorder: a double-blind, randomized controlled trial.

This double-blind, sham-controlled randomized trial evaluated accelerated intermittent theta burst stimulation (iTBS) targeting each participant’s personalized fronto-parietal network, alongside behavioral training, in…

Mol PsychiatryApr 15, 2026Read summary
Case ReportPsychiatry

Aripiprazole‑induced akathisia associated with bilateral putaminal hypermetabolism on PET.

A woman in her 50s with bipolar disorder and autoimmune diseases developed marked akathisia after aripiprazole 10 mg/day was added to lithium.

Int Clin PsychopharmacolApr 14, 2026Read case
Clinical ResearchPsychiatryOpen access

What are the correlates of non-suicidal self-injury in children and adolescents? An umbrella systematic review of global evidence.

This umbrella systematic review synthesised meta-analyses of observational studies examining correlates of non-suicidal self-injury (NSSI) in children and adolescents.

Mol PsychiatryApr 14, 2026Read summary
Clinical ResearchPsychiatryOpen access

Research Review: Omega-3 supplementation to reduce antisocial behavior - a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis assessed whether omega-3 supplementation reduces antisocial behavior. It included 25 randomized controlled trials involving 2,889 participants and analysed effects using…

J Child Psychol PsychiatryApr 14, 2026Read summary
Clinical ResearchPsychiatry

The criterion validity of general and antisocial personality disorder-specific criterion A in the alternative model of personality disorders: A scoping review and meta-analysis.

This scoping review and meta-analysis examined the criterion validity of general Levels of Personality Functioning Scale (LPFS) measures and antisocial personality disorder (ASPD)-specific measures for assessing ASPD…

Personal DisordApr 13, 2026Read summary
Clinical ResearchPsychiatry

AI-Assisted Classical Piano Intervention for Enhancing Resilience, Mindfulness, and Emotional Processing in Young Adults With Mild-to-Moderate Anxiety or Depression.

This randomized controlled mixed-methods study compared therapist-led classical piano instruction with and without adaptive AI feedback in 120 Mandarin-speaking young adults aged 18–30 years with mild-to-moderate…

J Gen PsycholApr 13, 2026Read summary
Clinical ResearchPsychiatryOpen access

Effect of a group-based acceptance and commitment therapy intervention on cognitive emotion regulation and psychological flexibility in patients with bipolar disorder.

This randomized controlled trial assessed whether group-based acceptance and commitment therapy (ACT) added to treatment as usual (TAU) improved cognitive emotion regulation (CER) and psychological flexibility (PF) in…

Psychol PsychotherApr 11, 2026Read summary
Clinical ResearchPsychiatryOpen access

Physical Appearance Anxiety and Eating Disorders Symptomatology: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the association between physical appearance anxiety (PAA) and eating disorder (ED) symptomatology.

Scand J PsycholApr 10, 2026Read summary
Clinical ResearchPsychiatryOpen access

Associations Between Baseline Severity and Treatment Effects in Digital Interventions for Eating Disorders: A Meta-Regression.

This meta-analysis used study-level meta-regressions of 31 randomised controlled trials to examine whether baseline eating-disorder severity was associated with the effects and dropout of digital interventions compared…

Eur Eat Disord RevApr 10, 2026Read summary
Clinical ResearchPsychiatry

Long-term consequences of childhood sexual abuse: An umbrella review of diagnostic meta-analyses.

This umbrella review synthesised 38 meta-analyses of observational studies, covering about 20 million individuals, to map adult physical, psychiatric and behavioural outcomes associated with childhood sexual abuse…

EncephaleApr 9, 2026Read summary
Clinical ResearchPsychiatryOpen access

Emotion regulation skills training as an adjunctive treatment to narrative exposure therapy for posttraumatic stress disorder (PTSD) in refugees: a pilot randomized controlled trial.

This pilot randomized controlled trial compared Skills Training in Affective and Interpersonal Regulation for Refugees plus Narrative Exposure Therapy (STAIR-R + NET) with Supportive Problem-Solving plus NET in 71…

Eur J PsychotraumatolApr 8, 2026Read summary
Clinical ResearchPsychiatryOpen access

Phase-based versus non-phase-based psychological interventions for complex PTSD: a systematic review and meta-analysis.

This systematic review and meta-analysis compared phase-based psychological interventions with non-phase-based approaches for people with clinically significant complex PTSD symptoms, or PTSD with at least two…

Eur J PsychotraumatolApr 8, 2026Read summary

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