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1333 articles

September 202624

Clinical ResearchOtolaryngology (ENT)

Non-usage rates after paediatric cochlear implantation: A systematic review and meta-analysis.

This systematic review and meta-analysis examined long-term cochlear implant use among paediatric recipients, synthesising 29 studies involving 2,595 children.

Int J Pediatr OtorhinolaryngolSep 28, 2026Read summary
Clinical ResearchMedical Genetics

Efficacy and safety of garetosmab, an activin A-blocking antibody, in fibrodysplasia ossificans progressiva (OPTIMA): a randomised, double-blind, placebo-controlled, phase 3 trial.

OPTIMA was a multicentre, randomised, double-blind, placebo-controlled phase 3 trial assessing monthly intravenous garetosmab in adults with fibrodysplasia ossificans progressiva.

LancetSep 28, 2026Read summary
Clinical ResearchUrologyOpen access

Changes in renal function in patients with chronic kidney disease after ureteroscopy: a systematic review and meta-analysis from EAU endourology.

This systematic review and meta-analysis evaluated changes in estimated glomerular filtration rate (eGFR) after ureteroscopy (URS) or retrograde intrarenal surgery (RIRS) in patients with chronic kidney disease (CKD).

UrolithiasisSep 28, 2026Read summary
Clinical ResearchUrologyOpen access

Vibegron, mirabegron, and other add-on therapies for persistent overactive bladder symptoms in α1-blocker-treated men with benign prostatic hyperplasia: a systematic review and Bayesian network meta-analysis.

This systematic review and Bayesian network meta-analysis evaluated the efficacy and safety of vibegron, mirabegron, and other add-on therapies for overactive bladder symptoms in men with benign prostatic hyperplasia…

World J UrolSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Second-Line Systemic Therapy Following First-Line FOLFIRINOX or NALIRIFOX in Metastatic Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated second-line therapies following first-line FOLFIRINOX or NALIRIFOX in 3888 adults with metastatic pancreatic ductal adenocarcinoma.

J Gastrointest CancerSep 28, 2026Read summary
Clinical ResearchNeurology

Evaluating the Clinical Utility of TSPO-PET in MS and the Influence of Methodological Heterogeneity: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated TSPO-PET imaging in multiple sclerosis (MS) patients compared to healthy controls.

Neurol Neuroimmunol NeuroinflammSep 28, 2026Read summary
Clinical ResearchNeurology

Association between insular involvement and ECG abnormalities in ischemic stroke: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether insular involvement in ischemic stroke is associated with ECG abnormalities, using cohort and cross-sectional studies comparing patients with and without insular…

J Clin NeurosciSep 28, 2026Read summary
Clinical ResearchUrology

Escherichia coli Nissle 1917 for the prevention of recurrent uncomplicated urinary tract infections in women: a pilot randomized placebo-controlled trial.

This pilot multicenter randomized controlled trial evaluated the efficacy of Escherichia coli Nissle 1917 (EcN) in preventing recurrent uncomplicated urinary tract infections (rUTIs) in 50 women.

Arch Ital Urol AndrolSep 28, 2026Read summary
Clinical ResearchPediatrics

Effects of Teleintervention Maintenance Programs for Children (Age 6-12) and Adolescents (Age 13-18) With Overweight or Obesity-Promoting a Healthy Lifestyle: A Systematic Review.

This systematic review evaluated teleintervention maintenance programs for children (ages 6-12) and adolescents (ages 13-18) with overweight or obesity.

Pediatr ObesSep 28, 2026Read summary
Clinical ResearchPediatrics

Adherence to the Mediterranean Diet Is Associated With a Lower Risk of Obesity in Children Under 18 Years: A Comprehensive Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the relationship between adherence to the Mediterranean Diet (MedDiet) and obesity risk in children and adolescents.

Pediatr ObesSep 28, 2026Read summary
Clinical ResearchNephrology

Effectiveness and Safety of Virtual Reality Interventions for Symptom Management in Adults Undergoing Hemodialysis: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the effectiveness and safety of virtual reality (VR) interventions for symptom management in adults undergoing hemodialysis.

J Med Internet ResSep 28, 2026Read summary
Clinical ResearchUrology

Efficacy and safety of α1-adrenergic receptor antagonists in managing acute urinary retention secondary to benign prostatic hyperplasia: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy of α1-adrenergic receptor antagonists in managing acute urinary retention (AUR) due to benign prostatic hyperplasia (BPH).

Arch Ital Urol AndrolSep 28, 2026Read summary
Clinical ResearchCardiology

Effectiveness of elastic therapeutic taping in pain management after median sternotomy: A randomized controlled trial.

This randomized controlled trial evaluated the effectiveness of elastic therapeutic taping on postoperative pain and recovery in 195 patients undergoing coronary artery bypass grafting via median sternotomy.

PLoS OneSep 28, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Non-thyroidal illness syndrome and isolated low triiodothyronine as prognostic markers in acute illness: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the relationship between thyroid hormone alterations and mortality in critically ill and cardiovascular patients.

EndocrineSep 28, 2026Read summary
Clinical ResearchUrologyOpen access

Intraoperative positioning strategies to improve stone-free outcomes during retrograde intrarenal surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of intraoperative positioning strategies on stone-free outcomes during retrograde intrarenal surgery (RIRS) for renal calculi, involving 998 patients across…

World J UrolSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

A comparison of the efficacy of cognitive-behavioral stress management and acceptance and commitment therapy on the quality of life and fatigue of caregivers of patients with cancer: a randomized controlled trial.

This randomized controlled trial compared the efficacy of cognitive behavioral stress management (CBSM) and acceptance and commitment therapy (ACT) on the quality of life and fatigue in 66 caregivers of cancer patients.

Support Care CancerSep 28, 2026Read summary
Clinical ResearchGeriatrics

A study protocol evaluating the effectiveness of the older adult's digital health literacy (ODDHeaL) intervention.

This randomized controlled trial evaluates the effectiveness of the Older Adults Digital Health Literacy (ODDHeaL) intervention in improving digital health literacy among community-dwelling adults aged 55 and older.

PLoS OneSep 28, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Effects of blood flow restriction combined with visual feedback training on lower limb function and the serum levels of BDNF and VEGF in patients with stroke.

This randomized controlled trial examined the effects of blood flow restriction training (BFRT) combined with visual feedback training (VFT) on lower limb function and serum levels of BDNF and VEGF in 40 hospitalized…

PLoS OneSep 28, 2026Read summary
Clinical ResearchCardiology

Stenting Technique and Clinical Outcome in True Bifurcation PCI: Insights From the OCTOBER Trial.

The OCTOBER trial analyzed 1,201 patients undergoing percutaneous coronary intervention for true bifurcation lesions to compare outcomes of 1-stent versus 2-stent techniques.

JACC Cardiovasc IntervSep 28, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Effects of concurrent training sequence on cardiometabolic risk factors in patients with type 2 diabetes: a systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the effects of concurrent training sequences on cardiometabolic risk factors in patients with type 2 diabetes mellitus (T2DM).

EndocrineSep 28, 2026Read summary
Clinical ResearchOphthalmology

Comparative study on the clinical effectiveness of low-concentration cyclosporine eye drops in patients with dry eye disease.

This multicenter, randomized, double-blind Phase 2 trial evaluated the efficacy and safety of low-concentration cyclosporine eye drops (SCAI-001 0.01% and 0.02%) versus Restasis (0.05%) in patients with dry eye disease.

PLoS OneSep 28, 2026Read summary
Clinical ResearchMedical Genetics

Effect of prenatal genetic counseling on anxiety and test attitudes in pregnant women: a randomized trial.

This randomized controlled trial assessed the impact of prenatal genetic counseling on anxiety and attitudes towards prenatal diagnostic tests in 66 pregnant women.

Rev Esc Enferm USPSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Circulating tumour DNA and its clinical relevance in predicting progression-free survival and overall survival in patients with advanced breast cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic value of circulating tumour DNA (ctDNA) in predicting progression-free survival (PFS) and overall survival (OS) in patients with advanced breast cancer…

Breast Cancer Res TreatSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Mindful eating as a supportive intervention for breast cancer survivors: a pilot randomized controlled trial.

This pilot randomized controlled trial assessed whether a six-session mindful eating intervention added to treatment-as-usual (TAU) improved eating behaviors and body composition in breast cancer survivors.

Breast CancerSep 27, 2026Read summary

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