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1845 articles
July 202624
Long-term outcomes and exploratory analysis from a randomized phase 3 trial of radiation dose escalation in definitive chemoradiotherapy for locally advanced esophageal squamous cell carcinoma.
This randomized phase 3 trial evaluated the long-term outcomes of radiation dose escalation (60 Gy vs 50 Gy) in 324 patients with locally advanced esophageal squamous cell carcinoma (ESCC).
Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial.
The CaPP3 trial evaluated the efficacy of lower doses of aspirin (100 mg and 300 mg daily) compared to 600 mg daily in preventing Lynch syndrome cancers among 1866 participants with Lynch syndrome.
Comparative Efficacy of Non-opioid Analgesic Drugs for Chronic Cancer Pain: A Bayesian Network Meta-analysis.
This Bayesian network meta-analysis evaluated the efficacy of non-opioid analgesics for chronic cancer pain in 1845 patients across 23 randomized controlled trials.
The impact of maternal breast cancer diagnosis on the mother-child relationship: an updated systematic review.
This systematic review updated previous findings on the impact of maternal breast cancer diagnosis on mother-child relationships, analyzing 68 studies.
A Systematic Review and Meta-Analysis of Surgical Feasibility and Outcomes Following Neoadjuvant Immune Checkpoint Inhibition in Resectable Stage III and IV Melanoma.
This systematic review and random-effects meta-analysis assessed oncologic and perioperative outcomes after neoadjuvant immune checkpoint inhibition (ICI) followed by planned curative-intent surgery in adults with…
Dose Optimization of Dasatinib in Chronic-Phase Chronic Myeloid Leukemia: A Systematic Review and Meta-analysis of 50 mg Versus 100 mg Once Daily.
This systematic review and meta-analysis evaluated the efficacy and safety of dasatinib 50 mg versus 100 mg once daily in adults with chronic-phase chronic myeloid leukemia (CP-CML).
Feasibility, efficacy and safety of pressurized intraperitoneal aerosol chemotherapy (PIPAC) for hepatobiliary and pancreatic cancers with peritoneal metastases: A systematic review.
This systematic review evaluated the feasibility, efficacy, and safety of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in 332 adult patients with hepatobiliary and pancreatic cancers with peritoneal…
Effectiveness of comprehensive geriatric assessment with patient coaching on toxicity, premature treatment interruption, unplanned hospitalisations, and survival in older patients with solid tumours: Secondary endpoints of the G-oncoCOACH study.
This secondary analysis of the G-oncoCOACH study evaluated the impact of Comprehensive Geriatric Assessment (CGA) with patient coaching on toxicity, treatment interruptions, hospitalizations, and survival in older…
A systematic review of factors associated with the patient and diagnostic intervals in gastric cancer.
This systematic review examined factors influencing the patient and diagnostic intervals in gastric cancer, analyzing 8 studies from 2012 to 2025.
ProBIOPSY: A Multidisciplinary International Consensus on Standards for Prostate Biopsy.
The ProBIOPSY project aimed to standardize prostate biopsy procedures through an international consensus involving 34 experts. A systematic review and a modified Delphi process led to consensus on 29 of 36 stems (81%).
Metachronous Ectopic CRH-Secreting Tumors Detected by 68 Ga-Pentixafor PET/CT.
A 39-year-old woman with ACTH-dependent Cushing syndrome underwent pituitary surgery after BIPSS indicated a central source.
Clinical pharmacokinetics of afatinib: A systematic review.
This systematic review examined the clinical pharmacokinetics of afatinib in patients with non-small cell lung cancer (NSCLC) and solid tumors.
18 F-FDG and 68 Ga-Pentixafor PET/CT in a Patient With Castleman Disease.
A patient with Castleman disease presented with multiple cervical lymphadenopathy. Imaging with 18 F-FDG and 68 Ga-pentixafor PET/CT was performed to aid in the differential diagnosis from lymphoma.
Intersphincteric resection versus abdominoperineal resection for lower rectal cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis compared intersphincteric resection (ISR) and abdominoperineal resection (APR) for lower rectal cancer in 4502 patients.
Olaparib in HR-deficient, metastatic triple-negative breast and platinum-sensitive relapsed ovarian cancers without germline mutations in BRCA1/2: phase 2 EMBRACE trial.
The phase 2 EMBRACE trial evaluated olaparib in patients with platinum-sensitive relapsed high-grade serous ovarian cancer (HGSOC) and metastatic triple-negative breast cancer (TNBC) with non-germline BRCA mutations.
Impact of R0/R1 Margin Status on Overall Survival in Node-Positive Resected Pancreatic Ductal Adenocarcinoma: Meta-Analysis.
This meta-analysis examined the impact of R0 versus R1 margin status on overall survival in 19,206 patients with node-positive resected pancreatic ductal adenocarcinoma (PDAC).
Tyrosine kinase inhibitors in Kosaki/Penttinen syndromes: new reports, follow-up of treated individuals and literature review.
This report discusses four new cases of Kosaki Overgrowth Syndrome and Penttinen Syndrome treated with tyrosine kinase inhibitors (TKIs).
Comparison of epcoritamab, lenalidomide, and rituximab versus usual care in relapsed/refractory follicular lymphoma.
This comparative study evaluated the efficacy of epcoritamab combined with lenalidomide and rituximab (R2) versus standard care in patients with relapsed/refractory follicular lymphoma (R/R FL).
Pleural Fluid Cytology Detects Small Cell Carcinoma Transformation in EGFR-Mutant Lung Adenocarcinoma: A Case Report.
A 65-year-old woman with EGFR-mutant lung adenocarcinoma experienced a massive pleural effusion after initially responding to icotinib.
[ 18 F]FDG PET/CT versus pelvic MRI in preoperative diagnosis of lateral lymph node metastasis in rectal cancer: a meta-analysis.
[18F]FDG PET/CT and pelvic MRI were compared for their diagnostic accuracy in detecting lateral lymph node metastasis (LLNM) in rectal cancer through a meta-analysis of 23 studies involving 2,209 patients.
Ifebemtinib plus garsorasib as first-line treatment for KRAS G12C -mutated non-small-cell lung cancer in China: a multicentre, single-arm expansion cohort from a phase 1b/2 trial.
This multicentre, single-arm phase 2 trial evaluated the efficacy and safety of ifebemtinib plus garsorasib in 33 treatment-naive patients with KRAS G12C-mutated non-small-cell lung cancer (NSCLC) in China.
18 F-FAPI-04 PET/CT Outperforms 18 F-FDG in Detecting Multiple Muscle and Subcutaneous Adipose Tissue Involvement of Marginal Zone Lymphoma.
A 63-year-old man presented with marginal zone lymphoma (MZL) involving multiple muscles and subcutaneous adipose tissue, a rare occurrence.
Fusobacterium nucleatum and response to treatment in colon and rectal cancer: a systematic review.
This systematic review evaluated the association between Fusobacterium nucleatum (Fn) and treatment outcomes in colorectal cancer (CRC) across 11 studies involving 1571 patients.
177 Lu-FAP-2286 Therapy in a Patient of Advanced Metastatic Malignant Solitary Fibrous Tumor.
A 22-year-old male presented with an intracranial malignant solitary fibrous tumor. Following three courses of 177 Lu-FAP-2286 therapy, imaging with 68 Ga-FAP-2286 PET/CT demonstrated partial regression of the tumor.
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