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1845 articles
June 202624
Dordaviprone Maintenance After Allogeneic HCT for High-Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm.
This Phase I clinical trial evaluated the safety of dordaviprone maintenance therapy after allogeneic hematopoietic cell transplantation in 20 adults with high-risk acute myeloid leukemia (AML) or myelodysplastic…
Quality assessment, prognostic factors, and biomarkers for brain tumor analysis: a comprehensive systematic review.
This systematic review examines the advancements in imaging technologies, prognostic factors, and biomarkers for brain tumors.
Malignant Perivascular Epithelioid Cell Tumor (PEComa) of Left Adrenal Gland With Extensive Intravenous Tumor Thrombi: 18 F-FDG PET/CT Findings.
A 53-year-old woman with left lower back pain, anemia, proteinuria, and hematuria was found to have bilateral adrenal masses on ultrasonography.
Atypical Presentation of Metastatic Prostate Adenocarcinoma in the Presacral Space: A Case Report of Diagnostic Resection via the Kraske Approach.
A 69-year-old man presented with hematuria and a 4-cm presacral mass, initially thought to be a primary neurogenic tumor based on MRI findings.
Artificial intelligence in genitourinary oncology: publication trends and systematic review.
This systematic review analyzed publication trends and randomized controlled trials (RCTs) regarding artificial intelligence (AI) in genitourinary oncology.
Myoepithelioma-like tumor of the vulvar region shows a quiet genome and heterogeneous detectable mechanisms of SMARCB1 inactivation: Integrated analysis of two cases and review of the literature.
Two cases of myoepithelioma-like tumor of the vulvar region (MELTVR) were analyzed, characterized by uniform epithelioid to spindle cells in myxoid stroma and complete loss of INI1 expression.
Long-Term Follow-Up of JCOG1008, a Randomized Phase II/III Trial of Chemoradiotherapy Comparing 3-Weekly Cisplatin With Weekly Cisplatin in Postoperative Head and Neck Cancer.
The JCOG1008 trial evaluated the long-term outcomes of chemoradiotherapy with weekly versus 3-weekly cisplatin in 261 patients with postoperative high-risk locally advanced squamous cell carcinoma of the head and neck.
Comparison of [ 18 F]DCFPyL and [ 18 F]FAPI-74 PET/CT imaging in metastatic prostate cancer.
This prospective clinical trial compared the efficacy of PSMA-targeted [18F]DCFPyL and FAPI-targeted [18F]FAPI-74 PET/CT imaging in 39 patients with metastatic prostate cancer.
Perineural invasion in intrahepatic cholangiocarcinoma: Meta-analysis of prevalence, association with tumor features, and impact on survival.
This meta-analysis evaluated the prevalence and prognostic significance of perineural invasion (PNI) in intrahepatic cholangiocarcinoma (ICC) across 61 studies involving 15,502 patients.
Cognitive impairments associated with meningiomas and gliomas in adults: A systematic review.
This systematic review examined cognitive impairments in adults with untreated meningiomas and gliomas, analyzing 70 studies involving 4,277 patients.
Distinct outcome patterns according to RAS and BRAF status in MSI-H/dMMR mCRC treated with immune checkpoint inhibitors: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of RAS and BRAF mutational status on outcomes in patients with MSI-H/dMMR metastatic colorectal cancer (mCRC) treated with immune checkpoint inhibitors…
Nutritional Amino Acid Supplementation Reduces Severity and Enhances Recovery of Radiation-Induced Oral Mucositis: A Triple-Blind Randomized Clinical Trial.
This triple-blind randomized clinical trial evaluated the effects of oral L-arginine and L-glutamine supplementation on radiation-induced oral mucositis (RIOM) in 84 head and neck cancer patients.
Multi-ancestry genome-wide association meta-analysis of hepatocellular carcinoma identifies 15 risk loci including MAP3K9, DHRS1, MTTP, and 8q24.21.
This multi-ancestry genome-wide association meta-analysis examined germline susceptibility to all-cause hepatocellular carcinoma (HCC) across 15 cohorts, including 17,697 affected individuals and 2,715,683 controls.
Clinical outcomes of ferroptosis-inducing agents in glioblastoma: A systematic review of clinical trials.
This systematic review evaluated the clinical outcomes of ferroptosis-inducing agents in glioblastoma (GBM) patients. Fourteen studies were included, primarily focusing on sorafenib, with median progression-free…
Effects of laughter therapy in patients with cancer: A systematic review of randomized clinical trials.
This systematic review of randomized controlled trials evaluated the effects of laughter therapy in 1127 cancer patients. The findings suggest that laughter therapy probably leads to a significant reduction in anxiety…
Quality of life with palbociclib plus tamoxifen in hormone receptor-positive, HER2-negative advanced breast cancer: results from PATHWAY, an Asian international, double-blind, randomized phase 3 trial.
The PATHWAY trial evaluated the quality of life (QoL) in pre/peri or postmenopausal women with hormone receptor-positive, HER2-negative advanced breast cancer receiving palbociclib plus tamoxifen versus placebo plus…
Prospective study on the [ 18 F]FDOPA PET/CT role in the management of medullary thyroid cancer patients with high residual calcitonin level after surgery.
This multicenter prospective study evaluated the role of [18F]FDOPA PET/CT in managing medullary thyroid cancer (MTC) patients with high residual calcitonin levels post-surgery.
Mesenteric Fibromatosis Mimicking Metastasis of Neuroendocrine Tumor on 18 F-AlF-NOTA-Octreotide PET/CT and Contrast- Enhanced MRI : A Case Report.
A 52-year-old man with a history of resected G2 pancreatic neuroendocrine tumor presented with a new abdominal mass during follow-up.
Rare Vocal Cord Metastasis From Prostate Adenocarcinoma on 68 Ga-PSMA PET/CT : A Diagnostic Mimic.
A patient with prostate adenocarcinoma presented with a vocal cord metastasis, which was identified through 68 Ga-PSMA PET/CT imaging.
Germline variants and impact on lung cancer outcomes following chemotherapy: A systematic review.
This systematic review examined the impact of germline genetic variants on chemotherapy outcomes in lung cancer patients of European ancestry.
Two cases of durvalumab-induced Evans syndrome in biliary tract cancer.
Two men aged 71 and 73 with advanced hilar cholangiocarcinoma developed Evans syndrome while receiving durvalumab monotherapy after eight cycles of gemcitabine, cisplatin, and durvalumab.
Primary mucosal melanoma of the maxillary sinus with spontaneous rupture of liver metastasis.
A 60-year-old woman presented with intraperitoneal bleeding from spontaneous rupture of a liver metastasis. Transcatheter arterial embolization controlled the bleeding, and biopsy confirmed metastatic melanoma.
The role of capacitive hyperthermia as an adjunct treatment in oncology: a systematic review of randomized phase III trials.
This systematic review evaluated the efficacy of capacitive hyperthermia (cHT) as an adjunct treatment in oncology, focusing on randomized phase III trials involving cancer patients undergoing radiotherapy and/or…
Efficacy and safety of infigratinib in patients with refractory advanced gastric or gastroesophageal junction adenocarcinoma harboring FGFR2 gene amplification: a single-arm, multicenter phase 2 trial.
This phase 2, single-arm trial evaluated the efficacy and safety of infigratinib in 21 patients with refractory advanced gastric or gastroesophageal junction adenocarcinoma harboring FGFR2 gene amplification.
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