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1845 articles

June 202624

Clinical ResearchPediatrics

Systematic Review and Pooled Analysis of 1,021 Children With Pancreatic Tumors.

This systematic review analyzed 1,021 children with pancreatic tumors, revealing that solid pseudopapillary neoplasm (SPN) was the most common histology (70.4%).

J Surg ResJun 23, 2026Read summary
Clinical ResearchOncology (Medical)

Insurance, Race, and Socioeconomic Disparities in Receipt of Surgical Treatment for Melanoma in the United States: A Systematic Review.

This systematic review analyzed 43 studies involving 2,957,954 melanoma patients in the U.S. to assess how insurance status, race/ethnicity, and socioeconomic status affect access to surgical treatment.

J Surg ResJun 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Artificial Intelligence-Driven MRI for Cervical Nodal Metastasis Detection in Oral Squamous Cell Carcinoma: A Hierarchical Meta-Analysis of Diagnostic Accuracy.

This meta-analysis evaluated the diagnostic accuracy of AI-driven MRI for detecting cervical lymph node metastases in oral squamous cell carcinoma (OSCC) across 12 studies.

Head NeckJun 23, 2026Read summary
Case ReportOncology (Medical)

99m Tc-FAPI SPECT/CT Provides Superior Diagnostic Performance to 18 F-FDG in Poorly Differentiated Gastric Adenocarcinoma.

A 52-year-old woman with poorly differentiated gastric adenocarcinoma experienced early satiety following gastrectomy and chemotherapy. Initial imaging with CT and FDG PET/CT did not clearly indicate recurrence.

Clin Nucl MedJun 23, 2026Read case
Case ReportHematology

Unmanipulated Haploidentical Stem Cell Transplantation Outcome in a Pediatric Patient With CD27 Deficiency and EBV-Induced Diffuse Large B-Cell Lymphoma With Primary CNS Involvement.

A pediatric patient with CD27 deficiency developed EBV-associated diffuse large B-cell lymphoma with primary CNS involvement and experienced an early relapse.

J Pediatr Hematol OncolJun 23, 2026Read case
Clinical ResearchOncology (Medical)

ctDNA-Based MRD Detection in Stage III NSCLC Treated With Chemoradiotherapy and Durvalumab.

This Phase II multicenter clinical trial evaluated the role of ctDNA-based minimal residual disease (MRD) detection in patients with unresectable stage III NSCLC receiving chemoradiotherapy followed by durvalumab.

J Thorac OncolJun 23, 2026Read summary
Case ReportOtolaryngology (ENT)

Thyroid Cartilage Reconstruction With Titanium Mesh in Advanced Papillary Thyroid Carcinoma.

A patient with locally advanced papillary thyroid carcinoma underwent resection involving the thyroid cartilage, with the laryngeal mucosa preserved.

LaryngoscopeJun 23, 2026Read case
Clinical ResearchOncology (Medical)

Artificial intelligence in cervical cancer screening and triage: a role-stratified systematic review and bivariate meta-analysis.

This systematic review and bivariate meta-analysis evaluated the accuracy of artificial intelligence (AI) tools in cervical cancer screening across different clinical roles.

Curr Opin OncolJun 22, 2026Read summary
Clinical ResearchGeneral Surgery

5x-Multiplier Versus 3-Tier Model: A Pragmatic Randomized Clinical Trial for Discharge Opioid Prescriptions After Intra-Abdominal Cancer Surgery.

This pragmatic single-center randomized clinical trial compared two discharge opioid prescribing models in 150 adults undergoing major abdominal cancer surgery.

Ann SurgJun 22, 2026Read summary
Clinical ResearchHematology

Prognostic factors for patients with relapsed or refractory multiple myeloma who are initiating a fourth or later line car T-cell or bispecific antibody therapy: a systematic literature review and meta-analysis.

This systematic literature review and meta-analysis evaluated prognostic factors for patients with relapsed or refractory multiple myeloma undergoing fourth or later line CAR T-cell or bispecific antibody therapy.

Expert Rev HematolJun 22, 2026Read summary
Case ReportOncology (Medical)

Unusual morphologic features in molecularly defined high-grade sarcomas of the uterus.

This report details two cases of high-grade uterine sarcomas with unique genetic alterations. One case featured an FGFR1::TACC1 fusion and exhibited an atypical epithelioid morphology, while the other had an…

Ann Diagn PatholJun 22, 2026Read case
Case ReportMedical Genetics

An atypical RUNX1::ETV6::RUNX1 fusion in a pediatric patient with precursor B-cell acute lymphoblastic leukemia.

A 2-year-old male presented with precursor B-cell acute lymphoblastic leukemia (B-ALL) and was found to have an atypical RUNX1::ETV6::RUNX1 fusion.

Cancer GenetJun 21, 2026Read case
Clinical ResearchOncology (Medical)Open access

Prognostic Value of the Haemoglobin-Albumin-Lymphocyte-Platelet Score in Head and Neck Cancer: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the prognostic value of the haemoglobin-albumin-lymphocyte-platelet (HALP) score in head and neck cancer (HNC) patients.

Clin OtolaryngolJun 21, 2026Read summary
Case ReportOncology (Medical)Open access

Multidisciplinary treatment with durvalumab-containing regimens for mixed neuroendocrine-non-neuroendocrine neoplasm of the extrahepatic bile duct.

A 63-year-old man presented with jaundice and a bile duct tumor involving the perihilar-to-distal extrahepatic duct, with bulky lymph node metastases. Initial biopsy showed adenocarcinoma.

Clin J GastroenterolJun 21, 2026Read case
Case ReportPathology (Anatomic & Clinical)Open access

Cytological Features of Clear Cell Sarcoma in Exfoliative and Effusion Cytology Specimen-A Case Report and Literature Review.

A patient with metastatic clear cell sarcoma of soft tissue presented with malignant effusions in sputum, peritoneal fluid, and pericardial fluid.

Diagn CytopatholJun 20, 2026Read case
Clinical ResearchGastroenterologyOpen access

Quality of Life Endpoints in Advanced Gastrointestinal Cancer Trials: Systematic Review of Inclusion, Challenges, and Implications (2020-2024).

This systematic review examined the inclusion of quality of life (QoL) endpoints in 80 phase III clinical trials for advanced gastrointestinal cancers.

Clin Oncol (R Coll Radiol)Jun 20, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Efficacy and safety of darolutamide plus androgen-deprivation therapy in Black patients with metastatic hormone-sensitive prostate cancer from the phase 3 ARANOTE trial.

The ARANOTE phase 3 trial analyzed the efficacy and safety of darolutamide plus androgen-deprivation therapy (ADT) specifically in Black patients with metastatic hormone-sensitive prostate cancer.

Prostate Cancer Prostatic DisJun 20, 2026Read summary
Clinical ResearchEndocrinology

Targeting ncRNA control networks with engineered exosomes to overcome therapy resistance in thyroid cancer.

This systematic review evaluated the role of exosomal non-coding RNAs (ncRNAs) in therapy resistance in radioactive iodine-refractory papillary thyroid cancer (RAIR-PTC).

Crit Rev Oncol HematolJun 20, 2026Read summary
Clinical ResearchOncology (Medical)

SACI-IO HR+: a randomized phase II trial of sacituzumab govitecan with or without pembrolizumab in patients with metastatic hormone receptor-positive/HER2-negative breast cancer.

This randomized phase II trial evaluated the efficacy of sacituzumab govitecan (SG) with or without pembrolizumab in patients with metastatic hormone receptor-positive/HER2-negative breast cancer.

Ann OncolJun 20, 2026Read summary
Clinical ResearchOncology (Medical)

Computed tomography derived body composition and risk of anastomotic leakage following rectal cancer surgery: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the association between computed tomography (CT)-derived body composition metrics and anastomotic leakage (AL) risk in 5763 rectal cancer patients undergoing…

Clin Nutr ESPENJun 20, 2026Read summary
Case ReportMedical Genetics

Metachronous multiple insulinomas in oculo-facio-cardio-dental syndrome harboring a novel BCOR deletion: a case report with review of literature.

A female patient with genetically confirmed oculo-facio-cardio-dental (OFCD) syndrome, due to a novel BCOR deletion, presented with recurrent hypoglycemic episodes.

Endocr JJun 20, 2026Read case
Case ReportGeneral SurgeryOpen access

Single-Port Robotic Cytoreductive Surgery for Colon Cancer Peritoneal Recurrence with the da Vinci SP.

A 61-year-old female with colon cancer developed ovarian and peritoneal metastases 14 months post-laparoscopic right hemicolectomy.

Ann Surg OncolJun 19, 2026Read case
Case ReportOncology (Medical)Open access

Cytologic Detection of Metastatic Immature Teratomas in Two Young Patients With Unique Presentations.

Two young women presented with high-grade ovarian immature teratomas featuring metastatic immature neuroepithelial components.

Diagn CytopatholJun 19, 2026Read case
Clinical ResearchOncology (Medical)Open access

Fraction-dependent dose dynamics and clinical safety in high-risk neuroblastoma treated with [ 177 Lu]Lu-DOTATATE: results from the LuDO-N trial.

The LuDO-N trial evaluated the safety and dosimetry of a two-fraction regimen of [177Lu]Lu-DOTATATE in 14 patients with high-risk neuroblastoma.

Eur J Nucl Med Mol ImagingJun 19, 2026Read summary

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