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1297 articles
September 202624
Increasing topical sunscreen use in German outdoor workers: results of a non-randomised controlled intervention study.
This non-randomised controlled intervention study evaluated a workplace strategy to increase sunscreen use among outdoor workers in Germany. The intervention provided easy access to sunscreen and health education.
Effects of transcendental meditation on mental health and work productivity among university staff in Australia: A randomised controlled trial.
This two-arm, open-label randomised controlled trial assessed transcendental meditation (TM) among staff at an Australian university, comparing five-day training plus regular practice with usual wellbeing resources.
Safety and Immunogenicity of a PD-1-Enhanced HIV-1 Therapeutic DNA Vaccine: A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalating Phase I Clinical Trial in People With HIV-1 on Antiretroviral Therapy.
This randomized, double-blind, placebo-controlled phase I trial evaluated the safety and immunogenicity of ICVAX™, a PD-1-enhanced HIV-1 therapeutic DNA vaccine, in 45 adults with HIV-1 on antiretroviral therapy.
Ivonescimab plus chemotherapy as first-line treatment for advanced thymic carcinoma: preliminary results of a phase II trial with biomarker analyses.
This phase II trial evaluated ivonescimab combined with chemotherapy in seven patients with advanced thymic carcinoma. The study found a promising objective response rate (ORR) of 85.7% and a disease control rate (DCR)…
Effectiveness, safety and acceptability of mifepristone compared with other interventions in reproductive-age women using emergency contraception for the prevention of pregnancy: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness, safety, and acceptability of mifepristone compared to other emergency contraception methods in reproductive-age women.
Concordance between objective and subjective sleep measures of people with bipolar disorder: A systematic review and a meta-analysis.
This systematic review and meta-analysis examined agreement between objective and subjective sleep measures in people with bipolar disorder.
Contraceptive effectiveness and safety of ormeloxifene: a systematic review.
This systematic review evaluated the contraceptive effectiveness and safety of ormeloxifene among reproductive-age women, analyzing 14 studies.
Approved Medications for Substance Use Disorders: An Umbrella Review of Systematic Reviews and Completed Phase 3 Randomized Controlled Trials.
This PROSPERO-registered umbrella review synthesised systematic reviews and completed phase 3 randomised trials of approved and pipeline medications for substance use disorders worldwide.
EFFECTIVENESS AND SAFETY OF BIOSIMILAR ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR FOR RETINAL DISEASES: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness and safety of biosimilar antivascular endothelial growth factor (VEGF) compared to reference anti-VEGF injections for retinal diseases.
A phase 2 pharmacokinetic and pharmacodynamic dose-finding study of oral NEPA for chemotherapy-induced nausea and vomiting in pediatric patients with cancer.
This phase 2 randomized controlled trial assessed the pharmacokinetics, pharmacodynamics, efficacy, and safety of oral netupitant combined with oral palonosetron (NEPA) in pediatric patients (< 18 years) undergoing…
The Role of Eccentric Contraction Training in the Postoperative Rehabilitation of Patients With Total Knee Arthroplasty.
This randomized controlled trial investigated the effects of eccentric contraction training on functional recovery in 44 patients post-total knee arthroplasty (TKA).
Low Prevalence of Exploratory Biochemical Patterns Compatible with Osteomalacia in a Large Cohort of Participants with Low Serum 25-Hydroxyvitamin D Levels.
This study investigated the prevalence of biochemical patterns indicative of osteomalacia in a cohort with low serum 25-hydroxyvitamin D levels.
TACE combined with apatinib versus TACE alone for unresectable hepatocellular carcinoma in China: a cost-effectiveness and budget impact analysis.
This study evaluated the clinical efficacy and cost-effectiveness of transarterial chemoembolisation (TACE) combined with apatinib versus TACE alone for unresectable hepatocellular carcinoma in China.
Photodynamic Diagnosis of Actinic Keratosis: A Systematic Review.
This systematic review evaluated the effectiveness of photodynamic diagnosis (PDD) for actinic keratosis (AK) across 37 studies.
Reduced oxaliplatin exposure in gastrointestinal cancers: A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared reduced oxaliplatin exposure (ROE) with standard-duration oxaliplatin-based therapy in gastrointestinal cancers.
Candida tropicalis in environmental and animal reservoirs: a systematic review from a One Health perspective.
This systematic review examined Candida tropicalis in environmental and animal sources, synthesizing evidence on antifungal susceptibility, virulence-associated traits, and resistance mechanisms.
A Randomized Comparative Effectiveness Trial of Many-Features and Few-Features Variants of Semantic Feature Analysis Treatment for Naming Impairment in Aphasia.
This randomized comparative effectiveness trial tested whether the number of semantic features generated during semantic feature analysis (SFA) affects naming outcomes in 41 people with aphasia following left-hemisphere…
Acupuncture for chemotherapy-induced nausea and vomiting: An umbrella review of systematic reviews.
This umbrella review assessed invasive acupuncture for chemotherapy-induced nausea and vomiting (CINV), synthesizing existing systematic reviews and meta-analyses and conducting a renewed meta-analysis of primary…
Prenatal Mindfulness Training and Race-Related Vigilance: A Mixed-Methods Study Among Pregnant Women at Risk for Hypertensive Disorders.
This mixed-methods study, conducted within a randomized clinical trial, examined prenatal mindfulness training in 53 pregnant women of color at risk for hypertensive disorders.
Switching to Daily Doravirine/Islatravir (100/0.25 mg) Maintains Viral Suppression Through Week 48 Despite Baseline Non-Nucleoside Reverse Transcriptase Inhibitor Resistance-Associated Mutations or M184I/V in Proviral DNA.
This phase III clinical trial evaluated the effects of baseline resistance-associated mutations (RAMs) on the virologic response to doravirine/islatravir (DOR/ISL) in 1227 virologically suppressed adults with HIV-1.
Long-Term Psychodynamic Psychotherapy for Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the effectiveness of long-term psychodynamic psychotherapy (LTPP) for reducing depressive symptoms across 16 randomized controlled trials with 1992 participants.
Psychosocial stress and risk of first-ever stroke: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the link between psychosocial stress and the risk of first-ever stroke in a stroke-free population, analyzing 84 studies with over 4 million participants.
Randomized, placebo-controlled trial of N-acetylcysteine in Parkinson's disease patients: a pilot study.
This randomized, placebo-controlled pilot trial assessed the tolerability of oral N-acetylcysteine (NAC) 1200 mg/day in 42 Parkinson's disease patients over one year.
Effectiveness and Safety of Colorectal Cancer Screening Via Fecal Occult Blood Testing: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the effectiveness of colorectal cancer screening via fecal occult blood tests in adults aged 45-75.
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