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1999 articles

September 202624

Case ReportOphthalmology

Autologous rotational partial thickness scleral flap - A salvage technique for late leaking blebs with scleral fistula.

Two patients with late leaking blebs complicated by scleral fistulae underwent a modified autologous rotational partial-thickness scleral flap procedure.

Indian J OphthalmolSep 29, 2026Read case
Case ReportDermatology

Genital lichen sclerosus with complete introital obliteration presenting with chronic urinary retention.

A postmenopausal woman with hypothyroidism presented with chronic urinary retention caused by complete introital obliteration due to lichen sclerosus.

BMJ Case RepSep 29, 2026Read case
Clinical ResearchOncology (Medical)

Hypofractionated versus conventional fractionated postmastectomy radiotherapy for patients with high-risk breast cancer (CHN HYPOPMRT): 10-year outcomes from a randomised, non-inferiority, open-label, phase 3 trial.

This phase 3 randomized trial compared hypofractionated (43.5 Gy in 15 fractions) and conventional (50 Gy in 25 fractions) postmastectomy radiotherapy in 810 women with high-risk breast cancer.

Lancet OncolSep 29, 2026Read summary
Clinical ResearchOncology (Medical)

Heart rate variability suppression in cancer patients versus non-cancer controls: a systematic review and meta-analysis.

This systematic review and meta-analysis examined heart rate variability (HRV) in cancer patients compared to non-cancer controls, including 28 studies with 3232 participants.

Support Care CancerSep 29, 2026Read summary
Case ReportOphthalmology

Bilateral Vortex Keratopathy in a Patient Receiving Long-Term Ribociclib Therapy.

A 67-year-old woman with metastatic breast cancer was found on routine eye examination to have bilateral whorl-like corneal epithelial deposits after four years of continuous ribociclib therapy.

Eye Contact LensSep 29, 2026Read case
Clinical ResearchGastroenterologyOpen access

Diagnostic yield of Franseen biopsy needles in endoscopic ultrasound-guided tissue acquisition: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic performance of Franseen biopsy needles compared to standard needles in endoscopic ultrasound-guided tissue acquisition among adult patients.

PeerJSep 29, 2026Read summary
Clinical ResearchPulmonology

Effects of pulmonary rehabilitation on lung hyperinflation in patients with COPD: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether pulmonary rehabilitation (PR) affects static and dynamic lung hyperinflation in people with COPD.

Respir MedSep 29, 2026Read summary
Case ReportPediatricsOpen access

Neonatal Gastric Perforation Temporally Associated with Nasogastric Tube Insertion: A Case Report.

A preterm male neonate, born at 34 weeks and weighing 1.5 kg, developed acute abdominal distension and respiratory distress 12 hours after nasogastric tube insertion for feeding.

Int Med Case Rep JSep 29, 2026Read case
Case ReportHematologyOpen access

Refractory Acquired Thrombotic Thrombocytopenic Purpura in the Third Trimester of Twin Pregnancy: A Case Report.

A 29-year-old woman in her third trimester of a twin pregnancy presented with symptoms including palpitations, dyspnea, and oral bleeding, alongside severe thrombocytopenia.

Int Med Case Rep JSep 29, 2026Read case
Clinical ResearchCardiology

Vascular effects of dietary nitrate supplementation in older adults with coronary artery disease: A randomized, placebo-controlled, crossover pilot trial.

This randomized, double-blind, placebo-controlled crossover pilot trial assessed the safety, feasibility, and vascular effects of beetroot-derived dietary nitrate in eight older adults with confirmed coronary artery…

Exp GerontolSep 29, 2026Read summary
Case ReportCardiology

Iatrogenic Large Bowel Perforation Following Image-Guided Pericardiocentesis: A Case Report.

A 72-year-old man with multiple comorbidities underwent fluoroscopy-guided pericardiocentesis for a large pericardial effusion.

Am J Case RepSep 29, 2026Read case
Clinical ResearchGastroenterology

A systematic and critical review of measurement scales for evaluating gastrointestinal symptoms during exercise.

This systematic review evaluated 126 studies on measurement scales for gastrointestinal symptoms (GIS) during exercise, focusing on Likert-type and visual analog scales (VAS).

J Int Soc Sports NutrSep 29, 2026Read summary
Case ReportNeurologyOpen access

Scleromyxedema-Associated Myopathy and Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS) as manifestations of Monoclonal Gammopathy of Clinical Significance (MGCS): a disease spectrum between autophagy dysfunction and inflammation.

This report discusses two patients with Scleromyxedema-Associated Myopathy (SAM) and one with Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS), both associated with Monoclonal Gammopathy of Clinical…

J NeurolSep 29, 2026Read case
Case ReportAnesthesiologyOpen access

Delayed Recognition of a Cuff-Level Tracheal Rupture After Double-Lumen Endotracheal Tube Intubation for Thoracic Surgery: A Case Report.

An 81-year-old man underwent left upper lobectomy using a double-lumen endotracheal tube. Postoperatively, he developed persistent air leakage, atelectasis, and subcutaneous emphysema.

Int Med Case Rep JSep 29, 2026Read case
Clinical ResearchCardiology

Deep learning for cardiac CT segmentation for congenital heart disease: A systematic review.

This systematic review evaluates deep learning (DL) approaches for cardiac CT segmentation in congenital heart disease (CHD), analyzing 14 studies.

PLoS OneSep 29, 2026Read summary
Clinical ResearchOncology (Medical)

Efficacy and safety of T-DXd versus Other HER2-targeted therapies in second-line and later settings for HER2-positive metastatic breast cancer: A Bayesian network meta-analysis.

This Bayesian network meta-analysis evaluated the efficacy and safety of T-DXd compared to other HER2-targeted therapies in 3,339 patients with HER2-positive metastatic breast cancer after trastuzumab-based therapy.

PLoS OneSep 29, 2026Read summary
Clinical ResearchInfectious Diseases

Exploring the relationship between HIV Testing frequency and sexual behavior, prevention prophylaxis use among MSM in Southern China.

This randomized controlled trial investigated the relationship between HIV testing frequency, sexual behaviors, and prophylaxis use among 327 men who have sex with men (MSM) in Guangxi, China.

PLoS OneSep 29, 2026Read summary
Clinical ResearchGeriatricsOpen access

Dual Sensory Impairment and Depressive Symptoms: Association and Pathways in Three Cohorts and a Meta-Analysis.

This meta-analysis examined the relationship between dual sensory impairment (DSI) and depressive symptoms in three aging cohorts: CHARLS, HRS, and ELSA.

Depress AnxietySep 29, 2026Read summary
Case ReportMedical Genetics

FOXG1 syndrome: genetic background revealed by trio WES in case of a critically ill neonate.

A male neonate presented with hypotonia and abnormal respiratory effort at birth. Due to the serious and non-specific clinical signs, trio whole-exome sequencing (WES) was performed, revealing a de novo heterozygous…

Ideggyogy SzSep 29, 2026Read case
Case ReportMedical GeneticsOpen access

Severe neurodevelopmental phenotype with multisystem involvement in VPS16-related mucopolysaccharidosis-like syndrome.

A patient with biallelic VPS16 variants presented with profound developmental delay, early-onset epilepsy, and spasticity, alongside multisystem issues such as recurrent infections and neutropenia.

NeurogeneticsSep 29, 2026Read case
Case ReportMedical Genetics

Longest surviving patient with a homozygous splice-altering EGFR pathogenic variant presenting with skin autoinflammation and a Bartter-like salt-losing tubulopathy.

An adolescent patient with a Bartter-like phenotype presented with progressive nephrocalcinosis, hypercalciuria, and skin autoinflammation.

J Med GenetSep 29, 2026Read case
Case ReportMedical Genetics

A rare case of hereditary spastic paraplegia with homozygous mutation in the ZFYVE26 gene.

A 19-year-old female with consanguineous parents presented with gait disturbances, lower limb spasticity, and dysarthria. Neurological examination revealed motor and mental retardation, bilateral lower limb spasticity…

Ideggyogy SzSep 29, 2026Read case
Clinical ResearchAllergy & Immunology

Short-term nasal decongestant as bridge therapy with intranasal corticosteroids in children with persistent allergic rhinitis: A randomized controlled trial.

This prospective, open-label, single-centre randomised trial compared intranasal corticosteroid (INS) alone with INS plus five days of oxymetazoline in children aged 4–17 years with moderate-to-severe persistent…

Int J Pediatr OtorhinolaryngolSep 29, 2026Read summary
Clinical ResearchCardiology

Sirolimus Versus Paclitaxel Drug-Coated Ballons for Femoropopliteal Disease: The LIMUS FLOW Trial.

The LIMUS FLOW proof-of-concept randomized controlled trial compared sirolimus-coated balloons (SCBs) with paclitaxel-coated balloons (PCBs) for severe femoropopliteal peripheral artery disease in 70 patients.

J Am Heart AssocSep 29, 2026Read summary

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