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1999 articles

September 202624

Clinical ResearchOphthalmologyOpen access

Nine-year ocular developmental outcomes after ranibizumab or laser treatment for zone II retinopathy of prematurity: follow-up of a randomized trial cohort.

This study followed a randomized trial cohort to assess 9-year ocular developmental outcomes in children treated with intravitreal ranibizumab (IVR) or laser photocoagulation (LP) for zone II retinopathy of prematurity…

Eur J PediatrSep 28, 2026Read summary
Clinical ResearchOrthopedic Surgery

Multicentre randomised controlled trial protocol in China comparing postless hip arthroscopy with conventional perineal post-assisted hip arthroscopy to reduce perineal complications in patients undergoing hip arthroscopy for femoroacetabular impingement: the POSTLESS-HIP trial.

The POSTLESS-HIP trial is a multicentre, prospective, parallel-group, randomised controlled trial in China evaluating postless hip arthroscopy versus conventional perineal post-assisted hip arthroscopy in 270 patients…

BMJ OpenSep 28, 2026Read summary
Clinical ResearchCardiologyOpen access

Effects of natriuresis-guided diuretic therapy in men and women with acute heart failure: insights from PUSH-AHF.

This exploratory sex-specific analysis of the multicentre randomised PUSH-AHF trial examined natriuresis-guided diuretic therapy versus standard care in 310 patients with acute heart failure, 45% of whom were women.

Clin Res CardiolSep 28, 2026Read summary
Clinical ResearchOncology (Medical)

Systemic and intracranial activity of antibody-drug conjugates in patients with non-small cell lung cancer and brain metastases: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed systemic and intracranial responses to antibody-drug conjugates (ADCs) in patients with non-small cell lung cancer and brain metastases.

Lung CancerSep 28, 2026Read summary
Case ReportMedical Genetics

Type A Insulin Resistance Syndrome Due to a Pathogenic Variant in the INSR Gene.

A woman in her 40s, initially diagnosed with type 1 diabetes, presented with a 30-year history of fluctuating insulin sensitivity and later developed insulin resistance, despite being non-obese.

Ir Med JSep 28, 2026Read case
Case ReportOphthalmology

Non-Arteritic Anterior Ischaemic Optic Neuropathy Associated with Semaglutide use.

A woman in her 70s with vascular risk factors presented with a three-day history of progressive left-sided visual disturbance. Examination revealed a left relative afferent pupillary defect and inferior quadrantopia.

Ir Med JSep 28, 2026Read case
Clinical ResearchPhysical Medicine & Rehabilitation

Shear wave elastography for assessing lower extremity muscle stiffness after anterior cruciate ligament reconstruction: A systematic review.

This systematic review synthesized studies using shear wave elastography (SWE) to assess lower-extremity muscle stiffness after anterior cruciate ligament reconstruction (ACLR), comparing reconstructed limbs with…

Clin Biomech (Bristol)Sep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Population Pharmacokinetics and Exposure-response Analysis of Durvalumab in Patients with Limited-stage Small-cell Lung Cancer in the Phase 3 ADRIATIC Study.

The ADRIATIC study evaluated the population pharmacokinetics and exposure-response relationships of durvalumab in patients with limited-stage small-cell lung cancer (LS-SCLC).

AAPS JSep 28, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

The effect of acute pain on proprioceptive performance: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether acute pain is associated with changes in behavioural proprioception measures.

J PainSep 28, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Current Evidence on Periprocedural Flat-Panel CT in Endovascular Stroke Treatment: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined periprocedural flat-panel CT (FPCT) findings and clinical applications in patients undergoing endovascular stroke treatment.

StrokeSep 28, 2026Read summary
Case ReportCardiology

Delayed cardiac conduction disease in a young adult following childhood Chagas infection.

A Bolivian man in his 30s presented to the emergency department with non-exertional chest pain and intermittent second-degree atrioventricular block.

Ir Med JSep 28, 2026Read case
Clinical ResearchGeriatrics

Healthcare spending and factors associated with fall injury in Australia residential aged care: a cohort analysis.

This cohort analysis examined healthcare spending and factors associated with fall injuries in Australian residential aged care, utilizing data from the Opti-Med trial involving 303 participants aged ≥65 years.

Inj PrevSep 28, 2026Read summary
Clinical ResearchNephrologyOpen access

Adherence to medical management of kidney stones: A systematic review.

This systematic review evaluated adherence to AUA guidelines for kidney stone management in adults, analyzing 35 studies with 57,970 patients.

UrolithiasisSep 28, 2026Read summary
Clinical ResearchEmergency Medicine

Efficacy of a needle-free blood collection device (PIVO Pro) for avoiding contaminated blood culture sets in Australian emergency departments: protocol for an adaptive group sequential randomised controlled trial.

This study protocol outlines a multicentre, adaptive group sequential randomised controlled trial aimed at evaluating the efficacy of the needle-free blood collection device, PIVO Pro, in reducing blood culture…

BMJ OpenSep 28, 2026Read summary
Case ReportOphthalmology

Buckle infection and exudative retinal detachment following a deep scleral bite: management and outcome.

During a standard 279 scleral buckle (SB) procedure, an inadvertent deep scleral suture bite occurred. On postoperative day (POD) 5, the patient presented with pain, reduced vision (counting fingers close to the face)…

BMJ Case RepSep 28, 2026Read case
Clinical ResearchGastroenterology

Evaluation of a Mental Health Care App-Based Fatigue Management Program for Patients With Inflammatory Bowel Disease in Remission: Protocol for a Randomized Controlled Trial.

This randomized controlled trial aims to evaluate a mobile cognitive behavioral intervention for fatigue management in patients with inflammatory bowel disease (IBD) in remission.

JMIR Res ProtocSep 28, 2026Read summary
Case ReportAnesthesiologyOpen access

Effects of Ciprofol- versus Remimazolam-Based Total Intravenous Anesthesia on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy: A Randomized Controlled Trial.

Postoperative nausea and vomiting (PONV) remains common after laparoscopic cholecystectomy. Whether ciprofol-based anesthesia reduces PONV compared with remimazolam-based anesthesia remains unclear.

Drug Des Devel TherSep 28, 2026Read case
Case ReportInfectious DiseasesOpen access

Diagnostic Challenges in mNGS for Pulmonary Mucormycosis Presenting with Imaging Features Resembling Those of Lung Cancer.

A 67-year-old woman with diabetes presented with cough and sputum production. Imaging suggested lung cancer due to a right hilar mass, bronchial obstruction, and mediastinal lymphadenopathy.

Int Med Case Rep JSep 28, 2026Read case
Case ReportCardiologyOpen access

Extracorporeal cardiopulmonary resuscitation for cardiogenic shock in a Jehovah's witness.

A Jehovah's Witness patient in cardiogenic shock underwent successful resuscitation using veno-arterial extracorporeal membrane oxygenation (ECMO) without the need for blood transfusions.

J Artif OrgansSep 28, 2026Read case
Clinical ResearchNeurologyOpen access

Endovascular Treatment for Patients Aged ≥80 Years with Large Ischemic Stroke.

This randomized controlled trial evaluated the effectiveness and safety of endovascular treatment (EVT) in patients aged ≥80 years with large ischemic stroke.

Clin Interv AgingSep 28, 2026Read summary
Clinical ResearchNeurologyOpen access

Intravenous thrombolysis use before interhospital transfer for thrombectomy: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of intravenous thrombolysis (IVT) before interhospital transfer for endovascular thrombectomy (EVT) in patients with large-vessel occlusion acute ischemic…

J NeurolSep 28, 2026Read summary
Case ReportNeurologyOpen access

Acrodynia and CASPR2 Autoimmunity in Elemental Mercury Toxicity.

A 2-year-old girl presented with cough, congestion, and later developed sweating, fussiness, and a pruritic rash after exposure to elemental mercury from a household spill.

J Med ToxicolSep 28, 2026Read case
Clinical ResearchNeurology

Prevalence of autoimmune comorbidities in aquaporin 4-immunoglobulin G positive neuromyelitis optica spectrum disorder: a systematic review and meta-analysis.

This systematic review and meta-analysis estimated the prevalence of autoimmune comorbidities among people with aquaporin-4-immunoglobulin G-positive neuromyelitis optica spectrum disorder.

Mult Scler Relat DisordSep 28, 2026Read summary
Clinical ResearchNephrology

A secondary analysis of the SODa-BIC randomized clinical trial using multiple hierarchical composite outcomes.

This post-hoc analysis of the SODa-BIC randomized trial evaluated the effects of sodium bicarbonate on Major Adverse Kidney Events at 30 days in critically ill patients with metabolic acidosis.

Crit Care SciSep 28, 2026Read summary

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