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262 articles

July 202616

Case ReportNeurosurgeryOpen access

Hybrid schwannoma-neurofibroma of the upper cervical spine: illustrative case and systematic review of spinal hybrid nerve sheath tumors.

A 25-year-old male presented with progressive cervical and left shoulder pain, along with intermittent numbness. MRI revealed a dumbbell-shaped intradural extramedullary lesion at the C1-2 level causing cervical cord…

Eur Spine JJul 25, 2026Read case
Case ReportNeurosurgeryOpen access

The "crumble disc sign": preoperative MRI predictor of intradural lumbar disc extrusion.

A 64-year-old woman with a history of lumbar surgery presented with recurrent L4-5 disc extrusion. Preoperative MRI revealed a unique 'crumble disc sign,' characterized by irregular and fragmented disc material within…

Skeletal RadiolJul 24, 2026Read case
Clinical ResearchNeurosurgeryOpen access

The vertebral artery loops: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed the prevalence of vertebral artery loops (VALs) in cervical spine surgery, analyzing 10 studies with 7,475 vertebral arteries.

Eur Spine JJul 23, 2026Read summary
Case ReportOncology (Medical)Open access

Clinical and Molecular Features of BAP1-Mutated Meningiomas: Case Series.

This report details three cases of BAP1-deficient meningiomas with distinct clinical outcomes. A 44-year-old woman with a somatic BAP1 mutation presented with recurrent spinal meningiomatosis despite low-grade…

Mol CarcinogJul 23, 2026Read case
Case ReportDermatologyOpen access

Cerebriform Ridges on the Scalp Signaling a Tumor in the Brain.

A 62-year-old man presented with longitudinal ridging of the scalp and features of acromegaly. Evaluation revealed a pituitary tumor responsible for his acromegaly and the associated cutaneous manifestation of cutis…

Perm JJul 23, 2026Read case
Clinical ResearchOrthopedic Surgery

NSAID Use and Bone Healing: An Umbrella Review with a Reconstructed Meta-Analysis.

This umbrella review and reconstructed meta-analysis examined whether NSAID exposure is associated with impaired bone healing and whether risk varies by patient group, procedure, dose, and duration.

J Am Acad Orthop SurgJul 21, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

A systematic review and meta-analysis of the diagnostic accuracy of angiographic techniques in spinal vascular malformations.

This systematic review and meta-analysis evaluated the diagnostic accuracy of magnetic resonance angiography (MRA), computed tomography angiography (CTA), and three-dimensional rotational angiography (3D RA) compared to…

Clin ImagingJul 17, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Restorative neurostimulation outcomes for mechanical chronic low back pain: delayed-start crossover from optimal medical management and 2-year treatment longitudinal analyses from the RESTORE randomized controlled trial.

This postmarket, multicentre, open-label randomised controlled trial extension evaluated restorative neurostimulation for mechanical chronic low back pain associated with lumbar multifidus dysfunction.

Spine JJul 16, 2026Read summary
Case ReportNeurosurgery

A Two-Handed Technique in Biportal Endoscopic Spine Surgery Using an Endoscopic Self-Retractor for Resection of Ossification of Ligamentum Flavum in Thoracic Spine.

Biportal endoscopic spine surgery commonly employs a single-handed technique despite the presence of dual portals. An endoscopic self-retractor attached to the viewing trocar enables true bimanual manipulation.

Clin Spine SurgJul 14, 2026Read case
Case ReportNeurosurgery

Penetrating thoracic spinal cord injury caused by a wooden fragment after a ground-level fall: A case report.

An elderly man sustained complete paraplegia after a wooden fragment from a shoji screen penetrated his back during a ground-level fall.

Am J Emerg MedJul 13, 2026Read case
Case ReportEmergency Medicine

Pneumocephalus Without Visible Fracture Preceding Subdural Empyema: A Delayed Emergency Department Diagnosis.

A 16-year-old male presented to the emergency department after minor blunt frontal trauma. Initial cranial CT showed no fractures or acute pathology, leading to his discharge.

J Emerg MedJul 11, 2026Read case
Clinical ResearchNeurosurgeryOpen access

Intraoperative neuromonitoring in degenerative cervical myelopathy surgery: a systematic review and meta-analysis of diagnostic accuracy and postoperative neurological outcomes.

This systematic review and meta-analysis evaluated the diagnostic accuracy of intraoperative neurophysiological monitoring (IONM) and its impact on postoperative outcomes in 154,972 patients undergoing surgery for…

Eur Spine JJul 8, 2026Read summary
Case ReportOncology (Medical)

177 Lu-FAP-2286 Therapy in a Patient of Advanced Metastatic Malignant Solitary Fibrous Tumor.

A 22-year-old male presented with an intracranial malignant solitary fibrous tumor. Following three courses of 177 Lu-FAP-2286 therapy, imaging with 68 Ga-FAP-2286 PET/CT demonstrated partial regression of the tumor.

Clin Nucl MedJul 7, 2026Read case
Clinical ResearchAnesthesiology

Effects of sub-anesthetic doses of esketamine on immune function and postoperative negative emotions in acoustic neuroma patients: a randomized clinical trial.

This randomized controlled trial evaluated the effects of sub-anesthetic esketamine on postoperative negative emotions and immune function in 84 patients undergoing acoustic neuroma surgery.

Ann MedJul 3, 2026Read summary
Clinical ResearchNeurosurgery

Surgical strategies after failed hemispheric disconnection surgery: A systematic review and individual-patient data analysis.

This systematic review analyzed surgical outcomes after failed hemispheric disconnection surgery in patients of all ages. The study found that redo hemispheric surgery (RHS) achieved Engel I outcomes in 50% of cases and…

SeizureJul 2, 2026Read summary
Clinical ResearchNeurosurgery

Tumor control and cranial nerve outcomes after Gamma Knife radiosurgery for Glomus jugulare tumors: a systematic review, meta-analysis, and institutional failure pattern analysis.

This systematic review and meta-analysis evaluated the outcomes of Gamma Knife radiosurgery (GKRS) for glomus jugulare tumors across 26 cohorts, involving 590 tumors.

J Clin NeurosciJul 1, 2026Read summary

June 20268

Clinical ResearchOncology (Medical)

Quality assessment, prognostic factors, and biomarkers for brain tumor analysis: a comprehensive systematic review.

This systematic review examines the advancements in imaging technologies, prognostic factors, and biomarkers for brain tumors.

Clin Chim ActaJun 26, 2026Read summary
Clinical ResearchNeurology

Clinical response after cerebrospinal fluid shunting in complex versus pure idiopathic normal pressure hydrocephalus: A systematic review and meta-analysis.

This systematic review and meta-analysis examined shunt outcomes in patients with pure idiopathic normal pressure hydrocephalus (iNPH) versus complex iNPH, which often coexists with other neurodegenerative diseases.

Clin Neurol NeurosurgJun 25, 2026Read summary
Clinical ResearchOrthopedic Surgery

3D-printed porous titanium vs polyetheretherketone cages in lumbar interbody fusion: a prospective, multicenter, randomized controlled trial with bone mineral density stratification.

This prospective, multicenter randomized controlled trial compared 3D-printed porous titanium with PEEK cages for single-level lumbar interbody fusion in patients with degenerative lumbar disease, including analyses…

Spine JJun 25, 2026Read summary
Clinical ResearchNeurosurgery

Designing a novel program for emergency neurosurgical task-sharing in Indonesia: Evidence base from a meta-analysis of global task-sharing outcomes.

This meta-analysis evaluated global outcomes of emergency cranial procedures performed by general surgeons in the absence of on-site neurosurgeons, focusing on their applicability in Indonesia.

J Clin NeurosciJun 24, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Effects of excessive distraction during anterior cervical spine surgery: a systematic review and meta-analysis of clinical outcomes, radiological changes, and complications.

This systematic review and meta-analysis evaluated the effects of excessive distraction (ED) during anterior cervical spine surgeries in 1877 patients.

Eur Spine JJun 24, 2026Read summary
Case ReportNeurosurgery

18 F FDG and 68 Ga FAPI PET/CT Findings in a Pituitary Abscess Secondary to Tuberculous Meningitis.

A patient presented with a pituitary abscess secondary to tuberculous meningitis, a rare and serious condition. Imaging with both 18 F FDG and 68 Ga FAPI PET/CT was performed, revealing the abscess.

Clin Nucl MedJun 24, 2026Read case
Case ReportNeurosurgery

Supratentorial intraparenchymal schwannoma: Systematic review of the literature with an illustrative case.

A 23-year-old female presented with a right frontal intraparenchymal schwannoma, which was successfully resected via craniotomy.

J Clin NeurosciJun 22, 2026Read case
Clinical ResearchNeurosurgeryOpen access

Deep brain stimulation of the nucleus accumbens for severe self-injurious behaviour in children: long-term outcomes from a first-in-human pilot trial.

This prospective, single-centre, first-in-human clinical trial assessed bilateral nucleus accumbens deep brain stimulation in six children and adolescents aged 7–14 years with profound autism and treatment-refractory…

Mol PsychiatryJun 22, 2026Read summary

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