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1002 articles

September 202624

Clinical ResearchInfectious Diseases

Effectiveness and safety of the available preventive tuberculosis treatment regimens for children and adolescents: systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the effectiveness and safety of tuberculosis (TB) treatment regimens in children and adolescents under 18 years.

BMJ Paediatr OpenSep 30, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Supporting Caregivers Behind Youth with T1D: A Systematic Review of Psychosocial Interventions and Youth Glycemic Outcomes.

This systematic review analyzed 26 studies on psychosocial interventions for parents of children with Type 1 Diabetes (T1D) from 2019 to 2025.

Curr Diab RepSep 30, 2026Read summary
Case ReportPediatricsOpen access

Isolated clival Langerhans cell histiocytosis in a pediatric patient: systematic review and illustrative case report.

A 3.5-year-old boy presented with isolated clival Langerhans cell histiocytosis, confirmed through histopathological and immunohistochemical evaluation.

Childs Nerv SystSep 30, 2026Read case
Case ReportPediatricsOpen access

Thalamic Tuberculoma Presenting as Isolated Gait Disturbance Without Systemic or Meningeal Symptoms in a 2-Year-Old Child: A Case Report.

A 2-year-old boy presented with isolated gait disturbance and decreased power on the left side, without systemic or meningeal symptoms.

Int Med Case Rep JSep 30, 2026Read case
Clinical ResearchPediatrics

The association between disability and mortality among children and adolescents: A systematic review and meta-analysis.

This systematic review and meta-analysis examined all-cause mortality among children and adolescents with disabilities compared to non-disabled peers, analyzing 29 studies with over 35 million participants.

PLoS MedSep 30, 2026Read summary
Clinical ResearchPediatrics

Does a Simple Touch Make a Difference? The Effect of Acupressure on Pain Scores in Infants Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled Trial.

This randomized, placebo-controlled trial evaluated acupressure in 60 infants aged 1–12 months with congenital heart disease undergoing cardiac catheterization.

J Cardiovasc NursSep 30, 2026Read summary
Clinical ResearchPediatrics

The Effect of Oropharyngeal Colostrum Administration on Early Feeding Skills and Transition to Oral Feeding in Preterm Infants: A Randomized Controlled Trial.

This randomized controlled trial investigated the impact of oropharyngeal colostrum administration on oral feeding readiness in 60 preterm infants (26 0 to 33 6/7 weeks gestation).

Adv Neonatal CareSep 29, 2026Read summary
Case ReportMedical Genetics

FOXG1 syndrome: genetic background revealed by trio WES in case of a critically ill neonate.

A male neonate presented with hypotonia and abnormal respiratory effort at birth. Due to the serious and non-specific clinical signs, trio whole-exome sequencing (WES) was performed, revealing a de novo heterozygous…

Ideggyogy SzSep 29, 2026Read case
Clinical ResearchPediatrics

Effect of strengths-based, tiered, accessible resources and supports (STARS) for Kids project, a codesigned hybrid service delivery framework to identify and support child development, parent mental health and psychosocial needs among parents and carers of children aged 6 months to 3 years: a randomised controlled trial protocol.

This randomized controlled trial protocol evaluates the STARS for Kids model, designed to enhance early identification and support for child development and parental mental health among parents of children aged 6 months…

BMJ OpenSep 29, 2026Read summary
Clinical ResearchPediatricsOpen access

Oral glucose solution for the treatment of persistent asymptomatic neonatal hypoglycemia: a randomized, double-blind, placebo-controlled trial.

This multicenter, randomized, double-blind, placebo-controlled trial evaluated the efficacy of buccal 50% dextrose solution (D50W) in treating persistent asymptomatic hypoglycemia in at-risk late preterm and term…

Eur J PediatrSep 29, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness and safety of subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease.

Eur J PediatrSep 29, 2026Read summary
Clinical ResearchOrthopedic Surgery

What to do with K-wires in displaced upper extremity fractures in children - where to bury or not.

This systematic review and meta-analysis evaluated the complication rates of buried versus exposed Kirschner wires (K-wires) in pediatric upper extremity fractures, involving 1,977 patients.

Eur J Trauma Emerg SurgSep 29, 2026Read summary
Case ReportPediatricsOpen access

Neonatal Gastric Perforation Temporally Associated with Nasogastric Tube Insertion: A Case Report.

A preterm male neonate, born at 34 weeks and weighing 1.5 kg, developed acute abdominal distension and respiratory distress 12 hours after nasogastric tube insertion for feeding.

Int Med Case Rep JSep 29, 2026Read case
Clinical ResearchAllergy & Immunology

Short-term nasal decongestant as bridge therapy with intranasal corticosteroids in children with persistent allergic rhinitis: A randomized controlled trial.

This prospective, open-label, single-centre randomised trial compared intranasal corticosteroid (INS) alone with INS plus five days of oxymetazoline in children aged 4–17 years with moderate-to-severe persistent…

Int J Pediatr OtorhinolaryngolSep 29, 2026Read summary
Clinical ResearchPediatrics

Effects of Teleintervention Maintenance Programs for Children (Age 6-12) and Adolescents (Age 13-18) With Overweight or Obesity-Promoting a Healthy Lifestyle: A Systematic Review.

This systematic review evaluated teleintervention maintenance programs for children (ages 6-12) and adolescents (ages 13-18) with overweight or obesity.

Pediatr ObesSep 28, 2026Read summary
Clinical ResearchPediatrics

Adherence to the Mediterranean Diet Is Associated With a Lower Risk of Obesity in Children Under 18 Years: A Comprehensive Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the relationship between adherence to the Mediterranean Diet (MedDiet) and obesity risk in children and adolescents.

Pediatr ObesSep 28, 2026Read summary
Case ReportNeurologyOpen access

Acrodynia and CASPR2 Autoimmunity in Elemental Mercury Toxicity.

A 2-year-old girl presented with cough, congestion, and later developed sweating, fussiness, and a pruritic rash after exposure to elemental mercury from a household spill.

J Med ToxicolSep 28, 2026Read case
Clinical ResearchOtolaryngology (ENT)

Non-usage rates after paediatric cochlear implantation: A systematic review and meta-analysis.

This systematic review and meta-analysis examined long-term cochlear implant use among paediatric recipients, synthesising 29 studies involving 2,595 children.

Int J Pediatr OtorhinolaryngolSep 28, 2026Read summary
Clinical ResearchHematology

Carfilzomib plus induction chemotherapy for children with relapsed or refractory acute lymphoblastic leukemia.

This phase II clinical trial evaluated the efficacy of carfilzomib combined with induction chemotherapy (CFZ-VXLD) in pediatric patients aged 1 month to <21 years with relapsed or refractory acute lymphoblastic leukemia…

Blood AdvSep 26, 2026Read summary
Case ReportNeurology

Biomarker-Guided Diagnosis of Riboflavin Transporter Deficiency Presenting as Seronegative Myasthenia Gravis: A Short Report from a Consanguineous Family.

A 3.5-year-old girl born to consanguineous parents developed bilateral ptosis, followed by dysphagia, dysphonia, facial diplegia, stridor, and respiratory compromise.

Genet Test Mol BiomarkersSep 26, 2026Read case
Clinical ResearchPediatrics

Turning distress into distraction: using virtual reality during penicillin injections for rheumatic fever.

This phase IIA clinical trial evaluated the use of immersive virtual reality (VR) during subcutaneous penicillin injections in 10 participants aged 9-20 years with acute rheumatic fever.

N Z Med JSep 25, 2026Read summary
Case ReportNeurology

Child Neurology: Transient Global Amnesia Precipitated by a Valsalva Maneuver in an Adolescent.

A 16-year-old boy with no prior health issues experienced acute anterograde amnesia following a Valsalva maneuver during a school video.

NeurologySep 25, 2026Read case
Case ReportOrthopedic Surgery

Monolateral rail fixator in paediatric femoral osteomyelitis can be a patient-friendly alternative to conventional fixator.

A 6-year-old boy with chronic femoral osteomyelitis presented with pus discharge, pain, and difficulty walking after an initial drainage procedure.

BMJ Case RepSep 25, 2026Read case
Clinical ResearchPediatrics

Can we do better in identifying child developmental conditions early? Sensitivity and specificity of the Watch Me Grow Integrated (WMG-I) digital developmental screening and surveillance tool in Australia.

This randomized controlled trial evaluated the diagnostic accuracy of the 'Watch Me Grow Integrated' (WMG-I) digital developmental screening tool in 16-to-35-month-old children in Australia.

BMJ OpenSep 25, 2026Read summary

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