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1064 articles

September 202624

Case ReportMedical GeneticsOpen access

Case Report: Sustained Cognitive Improvement and Reversible Brain Hypoperfusion in the Context of Posterior Fossa Arachnoid Cyst Shunting Procedure in KBG Syndrome.

A patient with KBG syndrome and a posterior fossa arachnoid cyst underwent shunting due to progressive cyst enlargement. Preoperative assessments indicated severe autism spectrum disorder and cognitive impairments.

CerebellumSep 23, 2026Read case
Clinical ResearchPsychiatryOpen access

Long-Term Psychodynamic Psychotherapy for Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the effectiveness of long-term psychodynamic psychotherapy (LTPP) for reducing depressive symptoms across 16 randomized controlled trials with 1992 participants.

Depress AnxietySep 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Prenatal Mindfulness Training and Race-Related Vigilance: A Mixed-Methods Study Among Pregnant Women at Risk for Hypertensive Disorders.

This mixed-methods study, conducted within a randomized clinical trial, examined prenatal mindfulness training in 53 pregnant women of color at risk for hypertensive disorders.

J Cardiovasc NursSep 23, 2026Read summary
Clinical ResearchPsychiatryOpen access

Approved Medications for Substance Use Disorders: An Umbrella Review of Systematic Reviews and Completed Phase 3 Randomized Controlled Trials.

This PROSPERO-registered umbrella review synthesised systematic reviews and completed phase 3 randomised trials of approved and pipeline medications for substance use disorders worldwide.

CNS DrugsSep 23, 2026Read summary
Clinical ResearchPsychiatry

Effects of transcendental meditation on mental health and work productivity among university staff in Australia: A randomised controlled trial.

This two-arm, open-label randomised controlled trial assessed transcendental meditation (TM) among staff at an Australian university, comparing five-day training plus regular practice with usual wellbeing resources.

J Affect DisordSep 23, 2026Read summary
Clinical ResearchPsychiatry

Concordance between objective and subjective sleep measures of people with bipolar disorder: A systematic review and a meta-analysis.

This systematic review and meta-analysis examined agreement between objective and subjective sleep measures in people with bipolar disorder.

J Affect DisordSep 23, 2026Read summary
Clinical ResearchCardiology

Ultra-processed food consumption and risk of multiple chronic diseases among 8,819,894 adults from 51 prospective cohorts: a dose-response meta-analysis.

This meta-analysis examined the relationship between ultra-processed food (UPF) consumption and the risk of chronic diseases in 8,819,894 adults across 51 prospective cohorts.

Fam Med Community HealthSep 22, 2026Read summary
Clinical ResearchPediatrics

A workbook- and audio-administered, telephone-guided, low-intensity cognitive behavioural therapy intervention (EJDeR) for parents of persons treated for cancer during childhood: protocol for the CHANGE-pilot randomised controlled trial.

The CHANGE-pilot trial is a parallel-group, two-arm, pilot randomized controlled trial assessing the feasibility of the EJDeR intervention, a low-intensity cognitive behavioural therapy for parents of children treated…

BMJ OpenSep 22, 2026Read summary
Case ReportNeurologyOpen access

Impulsivity, Compulsivity, Social Inappropriateness, and Other Neuropsychiatric Features in Cerebellar Histiocytosis.

This report describes six patients with multisystem Langerhans cell histiocytosis (LCH) who exhibited neurological and psychiatric disturbances linked to cerebellar lesions.

CerebellumSep 22, 2026Read case
Clinical ResearchPsychiatryOpen access

Work-focused cognitive behavioural therapy for common mental disorders: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of work-focused cognitive behavioural therapy (W-CBT) for common mental disorders (CMDs) in working-age adults.

BMC PsycholSep 22, 2026Read summary
Clinical ResearchPediatrics

Rapid Review of the Brief Observation of Social Communication Change (BOSCC) Shows It Can Detect Behavioural Changes in Social Communication in Autism.

This rapid review evaluated the Brief Observation of Social Communication Change (BOSCC) in detecting behavioral changes in social communication among autistic children.

AutismSep 22, 2026Read summary
Clinical ResearchPsychiatry

Low-dose versus standard-dose antipsychotic treatment in first-episode schizophrenia: A secondary analysis of EUFEST data.

This secondary analysis of the open-label randomized EUFEST trial compared outcomes by dose group among 421 participants with first-episode schizophrenia.

Schizophr ResSep 22, 2026Read summary
Clinical ResearchPsychiatry

Task-based metacognition and insight in schizophrenia spectrum disorders: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether performance on behavioral metacognitive tasks is associated with insight in adults with schizophrenia spectrum or other psychosis spectrum disorders.

Schizophr ResSep 22, 2026Read summary
Clinical ResearchPsychiatry

Patterns, predictors and outcomes of the joint trajectories of positive and negative symptoms in patients with early psychosis: 12-year follow-up of the randomized controlled trial on extended early intervention.

This 12-year follow-up of a randomized controlled trial of extended early intervention examined joint positive and negative symptom trajectories in people with first-episode psychosis.

Schizophr ResSep 22, 2026Read summary
Clinical ResearchPsychiatry

Loneliness in migrants: Are there differences compared to non-migrants? A systematic review and meta-analysis.

This systematic review and meta-analysis examined loneliness in migrants compared with non-migrants, drawing on quantitative studies identified through searches of four databases.

Soc Sci MedSep 22, 2026Read summary
Clinical ResearchNeurology

A Brief emotion-focused psychodynamic intervention for fatigue, pain, and health-related quality of life in women with relapsing-remitting multiple sclerosis: A randomized pilot trial.

This randomized pilot trial assessed the feasibility and preliminary clinical outcomes of an eight-session individual emotion-focused psychodynamic intervention in 30 women with relapsing-remitting multiple sclerosis…

Mult Scler Relat DisordSep 22, 2026Read summary
Clinical ResearchPsychiatry

PTSD treatment impacts on pain: secondary analysis of sertraline, prolonged exposure, and their combination.

This randomized controlled trial analyzed the effects of PTSD treatments on pain in 196 veterans. It found that all treatment groups, including Prolonged Exposure plus placebo, Prolonged Exposure plus Sertraline, and…

Eur J PsychotraumatolSep 21, 2026Read summary
Clinical ResearchPsychiatry

Effectiveness of Telehealth Care Interventions for Women's Mental Health During and After the COVID-19 Pandemic: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effectiveness of telehealth interventions for improving mental health outcomes in women during and after the COVID-19 pandemic.

J Med Internet ResSep 21, 2026Read summary
Clinical ResearchPsychiatry

Supporting the Primary Outcomes of the Mirai Trial for the Adjunctive Digital Therapeutic Rejoyn (CT-152) in the Treatment of Major Depressive Disorder: Meaningful Change Analysis in the Montgomery-Åsberg Depression Rating Scale.

This randomized controlled trial analyzed the adjunctive digital therapeutic Rejoyn (CT-152) for major depressive disorder, focusing on the Montgomery-Åsberg Depression Rating Scale (MADRS).

JMIR Form ResSep 21, 2026Read summary
Clinical ResearchPsychiatry

An Open-Label, Dose-Escalation Trial of Psilocybin-Assisted Therapy for Bipolar II Depression.

This open-label, single-arm pilot trial evaluated the safety, tolerability, and preliminary efficacy of psilocybin therapy in 14 individuals with bipolar II disorder (BD-II) and depression.

J Clin PsychiatrySep 21, 2026Read summary
Clinical ResearchPsychiatry

How should we teach psychiatric formulation? A systematic review of the evidence.

This systematic review examined the literature on teaching psychiatric formulation, identifying gaps and inconsistencies in educational strategies and outcomes.

Psychol MedSep 21, 2026Read summary
Clinical ResearchPsychiatry

Effect of modernized collaborative care for depression on individual depressive symptoms: A secondary analysis of the eIMPACT trial.

This secondary analysis of the eIMPACT trial evaluated the effects of modernized collaborative care on individual depressive symptoms in 216 primary care patients.

Psychol MedSep 21, 2026Read summary
Clinical ResearchPsychiatry

Comparing lithium and valproate in reducing suicide risk: A territory-wide retrospective cohort study with pairwise and network meta-analysis.

This study evaluated the effectiveness of lithium versus valproate in reducing suicide risk among patients with bipolar disorder using a retrospective cohort design.

Psychol MedSep 21, 2026Read summary
Clinical ResearchPediatrics

Adjunctive psychobiotic Lactiplantibacillus plantarum PS128 ameliorates gastrointestinal comorbidities and alters circulating miRNAs and gut microbiota in children with Tourette syndrome: a randomized controlled trial.

This randomized controlled trial evaluated the effects of the psychobiotic Lactiplantibacillus plantarum PS128 on children aged 4-18 with Tourette syndrome.

Food FunctSep 21, 2026Read summary

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