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1999 articles

September 202624

Case ReportGeneral SurgeryOpen access

Delayed Metal Hypersensitivity from Surgical Clips Causing Progressive Neuropathy.

A 65-year-old male presented with progressive abdominal pain, bilateral lower extremity neuropathy, postprandial nausea, and autonomic dysfunction after laparoscopic cholecystectomy and inguinal hernia repair.

CRSLSSep 26, 2026Read case
Clinical ResearchPsychiatryOpen access

A machine learning-based ecological momentary intervention for mental health promotion in youth: a micro-randomized trial.

This micro-randomized trial investigated the effects of machine learning (ML)-based ecological momentary interventions (EMIs) on mental health outcomes in 49 youth participants.

Transl PsychiatrySep 26, 2026Read summary
Case ReportNeurology

Biomarker-Guided Diagnosis of Riboflavin Transporter Deficiency Presenting as Seronegative Myasthenia Gravis: A Short Report from a Consanguineous Family.

A 3.5-year-old girl born to consanguineous parents developed bilateral ptosis, followed by dysphagia, dysphonia, facial diplegia, stridor, and respiratory compromise.

Genet Test Mol BiomarkersSep 26, 2026Read case
Case ReportGastroenterology

Vulvar Crohn's-Case Series and Review of Treatment With Ustekinumab.

This case series presents three patients with cutaneous vulvar Crohn's disease (VCD), a rare and challenging condition. Each patient was treated with different biologic agents.

J Low Genit Tract DisSep 26, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Somatic PIK3CA and PTEN mutations with endothelial PI3K/AKT/mTOR activation in RAS-negative brain arteriovenous malformations.

This report details two autopsy-confirmed brain arteriovenous malformations (bAVMs) with somatic PIK3CA mutations, one of which also had a PTEN alteration.

J Neuropathol Exp NeurolSep 26, 2026Read case
Case ReportPsychiatryOpen access

Therapeutic drug monitoring-guided management of venlafaxine overdose in an adolescent: a case report.

An adolescent presented with severe venlafaxine overdose, exhibiting tachycardia, mydriasis, and generalized tonic-clonic seizures. Initial plasma levels were 7800 ng/mL, significantly above therapeutic limits.

J Anal ToxicolSep 26, 2026Read case
Clinical ResearchGastroenterology

Quantifying Pancreatic Fat Using a Free-Breathing Acquisition in Adults With Obesity Undergoing Diet-Induced Weight Loss-Results From the LION Study.

This randomized controlled trial evaluated a free-breathing six-echo radial stack-of-stars acquisition for quantifying pancreatic fat in 18 adults with obesity undergoing diet-induced weight loss.

NMR BiomedSep 26, 2026Read summary
Case ReportOphthalmology

Bacterial orbital infection leading to orbital exenteration: a case series.

This case series describes three people who underwent orbital exenteration for bacterial infection. Two infections arose from odontogenic sources; the third was periorbital/orbital necrotizing fasciitis associated with…

J Craniomaxillofac SurgSep 26, 2026Read case
Clinical ResearchObstetrics & Gynecology

Rethinking Prevention of Recurrent Bacterial Vaginosis: A Comparative Effectiveness Network Meta-Analysis.

This network meta-analysis evaluated the effectiveness of various preventive strategies for recurrent bacterial vaginosis (BV) in nonpregnant women.

J Low Genit Tract DisSep 26, 2026Read summary
Clinical ResearchEndocrinology

Empagliflozin Promotes Natriuresis in Diabetic Patients with Cirrhotic Refractory Ascites: A Proof-of-Concept Study.

This randomized controlled trial investigated the effects of empagliflozin on natriuresis in 21 diabetic patients with decompensated cirrhosis and refractory ascites.

J Gastrointestin Liver DisSep 26, 2026Read summary
Clinical ResearchNeurology

Single-Area Versus Multiple-Area Passive Recharge Burst During Spinal Cord Stimulator Trials: An Independent Prospective Randomized, Double-Blind Study.

This randomized controlled trial evaluated the effectiveness of single-area versus multi-area passive recharge burst therapy in a neurostimulation naive population for chronic pain management.

Pain PractSep 26, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Effectiveness of Lactobacillus-supplemented eradication therapy for Helicobacter pylori: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the effectiveness of Lactobacillus-supplemented Helicobacter pylori eradication therapy across 32 randomized controlled trials involving 4,010 patients.

Eur J Clin PharmacolSep 26, 2026Read summary
Case ReportGeriatrics

Electrical Impedance Tomography-Guided Precision Nursing in an Older Patient With Septic Shock and ARDS: A Case Report.

A 79-year-old patient with septic shock, ARDS, and MODS underwent precision nursing management utilizing electrical impedance tomography (EIT).

Nurs Crit CareSep 26, 2026Read case
Clinical ResearchObstetrics & Gynecology

Diagnostic Strategies After Negative Colposcopy in High-Grade Cervical Cytology: A Multicenter Randomized Trial.

This multicenter randomized trial evaluated diagnostic strategies for detecting HSIL+ in women with high-grade cervical cytology and negative colposcopy.

J Low Genit Tract DisSep 26, 2026Read summary
Clinical ResearchHematologyOpen access

ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review.

This systematic review evaluated the impact of ATM mutations in myelodysplastic neoplasms (MDS), acute myeloid leukemia (AML), and myeloproliferative neoplasms (MPN).

Med OncolSep 25, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Comparative pain relief and functional outcomes following robotic-assisted versus conventional total knee arthroplasty: a GRADE-assessed meta-analysis with meta-regression of randomized controlled trials.

This meta-analysis of 24 randomized controlled trials involving 3,425 patients compared robotic-assisted total knee arthroplasty (RA-TKA) with conventional TKA (C-TKA).

J Robot SurgSep 25, 2026Read summary
Case ReportInfectious DiseasesOpen access

Aggressive brainstem listeria abscess in an immunocompetent individual: A case report.

An immunocompetent patient in their late 50s presented with neurolisteriosis characterized by multifocal brainstem abscesses. The case involved an extensive negative infectious workup and a complex antibiotic regimen.

Neurol SciSep 25, 2026Read case
Clinical ResearchUrologyOpen access

Unravelling deregulated metabolites in seminal plasma of infertile men: a systematic review and bioinformatic analysis.

This systematic review analyzed metabolomic studies comparing seminal plasma metabolites in healthy and infertile men. It included 20 studies and identified 284 metabolites, with specific alterations linked to…

J Mol Med (Berl)Sep 25, 2026Read summary
Case ReportCardiothoracic Surgery

Cervical aortic arch with severe left ventricular dysfunction in a neonate: successful repair using whole-body perfusion.

A neonate presented with a right cervical aortic arch, coarctation, and significantly reduced left ventricular function. Surgical intervention involved arch repair with aortic uncrossing, utilizing whole-body perfusion…

Multimed Man Cardiothorac SurgSep 25, 2026Read case
Clinical ResearchOncology (Medical)Open access

Fasting-induced metabolic reprogramming as a therapeutic vulnerability in cancer: a systematic mechanistic review of in vitro evidence.

This systematic review evaluated in vitro studies on fasting and fasting-mimicking interventions in cancer cell models. It found that fasting consistently reduced IGF-1 signaling and inhibited key metabolic pathways…

Med OncolSep 25, 2026Read summary
Clinical ResearchGeriatricsOpen access

Metabolic reserve: baseline cholesterol as a predictor and modulator of response to in-hospital exercise in older adults.

This secondary analysis of a randomized controlled trial examined whether baseline nutritional biomarkers predicted functional response to multicomponent exercise among 303 hospitalized adults aged ≥75 years.

J Nutr Health AgingSep 25, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Comparative efficacy of brain-computer interface-coupled robotic rehabilitation, robot-assisted therapy, and motor imagery for upper-limb motor recovery after stroke: a systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the efficacy of brain-computer interface-coupled robotic rehabilitation (BCI-robot), robot-assisted therapy, motor imagery, and conventional rehabilitation for…

Neurol SciSep 25, 2026Read summary
Case ReportOncology (Medical)

Pure Red Cell Aplasia Following Neoadjuvant Docetaxel/Carboplatin/Trastuzumab (TCbH) in a 45‑Year‑Old Woman With Breast Cancer Successfully Treated With Cyclosporine.

A 45-year-old woman with HER2-positive breast cancer developed pure red cell aplasia (PRCA) after neoadjuvant treatment with docetaxel/carboplatin/trastuzumab.

Am J Case RepSep 25, 2026Read case
Clinical ResearchAllergy & Immunology

Asthma Intervention with Residential Ventilation and Air Cleaner (AIRVAC) Study: A 4-arm parallel-group randomized controlled trial protocol.

The AIRVAC study is a 4-arm parallel-group randomized controlled trial evaluating the long-term effectiveness of energy recovery ventilators and portable air cleaners in improving asthma outcomes among children and…

PLoS OneSep 25, 2026Read summary

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