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1999 articles
September 202624
The Use of Waivers of Guardian Permission in the United States for Pediatric Digital Health Intervention Research Since 2020: Systematic Review.
This systematic review examined the use of guardian permission waivers in pediatric digital health intervention research in the U.S. from 2020 to 2026.
Association Between Metabolic and Bariatric Surgery and Melanoma Risk: A Systematic Review and Meta-analysis of Observational Studies.
This systematic review and meta-analysis of observational studies assessed whether metabolic and bariatric surgery (MBS) was associated with melanoma incidence compared with no MBS.
Wearable Sensors in Gait Assessment for Parkinson Disease and Stroke in Real-World Environments: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the use of wearable sensors for gait assessment in patients with Parkinson disease (PD) and stroke. It included 43 studies, primarily focusing on PD (2774 participants).
Levels of IgG subclasses 1-4 in BT595, a 10% IVIG: A sub-analysis of a clinical trial.
This multicenter, open-label clinical trial evaluated the pharmacokinetics of IgG subclasses in patients with primary immunodeficiency receiving 10% IVIG BT595.
Temporally Based Orbicularis Oculi Myocutaneous Flap for Pediatric Postexcisional Cicatricial Lower Eyelid Ectropion: A Case Report.
A pediatric patient developed cicatricial lower eyelid ectropion after two local excisions of a congenital melanocytic nevus at another institution.
Predictors of Pulmonary Complications After Rib Fractures: Systematic Review and Meta-Analyses.
This systematic review and meta-analysis examined multivariable-adjusted predictors of pulmonary complications in adults with blunt rib fractures.
Blood pressure targets for hypertension in people with diabetes mellitus.
This Cochrane systematic review protocol aims to evaluate whether lower blood pressure targets (≤ 130/85 mmHg) reduce mortality and morbidity compared to standard targets (≤ 140 to 160/90 to 100 mmHg) in individuals…
Within-person variability and the minimal important difference of the EQ-VAS in adults with post-COVID-19 condition: a secondary analysis of data from a single-centre randomised controlled trial.
This secondary analysis of a randomized controlled trial evaluated the EuroQol Visual Analogue Scale (EQ-VAS) in adults with post-COVID-19 condition (PCC).
Can we do better in identifying child developmental conditions early? Sensitivity and specificity of the Watch Me Grow Integrated (WMG-I) digital developmental screening and surveillance tool in Australia.
This randomized controlled trial evaluated the diagnostic accuracy of the 'Watch Me Grow Integrated' (WMG-I) digital developmental screening tool in 16-to-35-month-old children in Australia.
Study on blueberries, protein and exercise for improving frailty and cardiovascular disease (STRONG): protocol for a parallel-group randomised controlled superiority trial in older Nova Scotians.
The STRONG study is a parallel-group randomized controlled trial aimed at assessing the impact of a year-long intervention involving blueberries, protein, and exercise on frailty and cardiovascular health in 240 older…
Clinical Reasoning: An Immunocompetent Young Adult With Acute Vision Loss.
A 23-year-old male presented with worsening headaches, bilateral retrobulbar pain, and blurred vision. Evaluation indicated bilateral optic neuritis, with MRI, CSF analysis, and blood tests showing normal results except…
Accuracy of Artificial Intelligence in Diagnosing Obstructive Sleep Apnea Using Photoplethysmography: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of AI-based methods using photoplethysmography (PPG) for obstructive sleep apnea (OSA) in adults.
Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.
ROAM/EORTC-1308 was an international, multicentre, open-label, phase 3 randomised trial comparing adjuvant radiotherapy with observation after complete resection of newly diagnosed WHO grade 2 atypical meningioma.
Intraosseous versus intravenous access in adult out-of-hospital cardiac arrest: a Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial.
This pre-planned Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial compared intraosseous-first with intravenous-first vascular access in adults with out-of-hospital cardiac arrest requiring…
Effectiveness of cognitive behavioral therapy for postpartum depression: a systematic review and meta‑analysis.
This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for postpartum depression (PPD), comparing it with usual care in randomized controlled trials.
The reduction in blood pressure required to reduce arterial stiffness components in SPRINT: a randomized controlled trial.
This analysis of the multicentre SPRINT randomised controlled trial examined whether blood pressure changes were associated with changes in arterial stiffness components over 1 year.
Nonlinear dose-response of mind-body exercise in older adults with mild cognitive impairment: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the dose-response relationship of mind-body exercise on cognitive function in older adults with mild cognitive impairment (MCI).
Iberdomide plus daratumumab and dexamethasone versus daratumumab, bortezomib, and dexamethasone in patients with relapsed or refractory multiple myeloma (EXCALIBER-RRMM): an open-label, randomised, controlled, phase 3 trial.
EXCALIBER-RRMM is an ongoing, open-label, randomised phase 3 trial comparing iberdomide, daratumumab, and dexamethasone with daratumumab, bortezomib, and dexamethasone in adults with relapsed or refractory multiple…
Sequential combination of anti-PD-1 antibody and PEG-IFNα in chronic hepatitis B patients: correlates of HBsAg loss with enhanced T-cell responses.
This pilot clinical trial investigated the sequential combination of anti-PD-1 antibody (sintilimab) and PEG-IFNα in ten virologically suppressed chronic hepatitis B patients.
Migration of an ingested orthodontic retainer into the psoas muscle presenting with radiculopathy-like symptoms: A case report.
A 26-year-old man presented with abdominal pain after swallowing an orthodontic retainer. Although his abdominal pain improved, he later experienced persistent right lower-limb paresthesia and pain.
Lymphocutaneous sporotrichosis: A case report from southeastern China and review of the literature.
A 53-year-old male presented with multiple ulcerated lesions, leading to a diagnosis of lymphocutaneous sporotrichosis. Pathological analysis showed an inflammatory reaction, while imaging studies were normal.
A previously unreported ELOVL4 frameshift variant in a patient with early severe cognitive decline, parkinsonism, and cerebellar ataxia: A case report.
A 35-year-old man presented with a 5-year history of progressive cognitive decline, parkinsonism, and cerebellar ataxia. Neurological examination revealed significant motor and cognitive impairments, with imaging…
Multimorbidity and the risk of depression: a systematic review of cohort studies.
This systematic review evaluated the longitudinal association between multimorbidity and the risk of developing depression, analyzing 17 cohort studies.
Effects of exercise interventions on gait, motor function, and balance in patients with Parkinson's disease: A meta-analysis with clinical implications.
This meta-analysis evaluated the effects of exercise interventions on gait, motor function, and balance in 714 patients with Parkinson's disease.
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