Trending archive
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1064 articles
September 202624
Feasibility and acceptability of the Unified Protocol for anxiety and depression in Pakistan: a pilot randomized controlled trial.
This pilot randomized controlled trial assessed the feasibility and acceptability of the Urdu Adapted Unified Protocol (UA-UP) for anxiety and depression in 51 adults in Pakistan.
A systematic review of clinical practice guidelines for suicide and self-harm prevention in adults.
This systematic review evaluated clinical practice guidelines for assessing, managing and treating adults who self-harm, with or without suicidal intent.
Anxiety disorders, PTSD, and risk of first-ever stroke: A meta-analysis of 11 million participants.
This meta-analysis pooled 23 longitudinal cohort studies involving 11,181,338 participants to assess whether anxiety disorders, obsessive-compulsive disorder (OCD), and PTSD were associated with first-ever stroke.
Heartbeat counting task performance in alcohol use disorder: a systematic review and meta-analysis.
This systematic review and meta-analysis examined heartbeat counting task (HCT) performance in adults with alcohol use disorder (AUD) compared to healthy controls (HC).
Subjective and objective memory effects after electroconvulsive therapy for depressive disorders - systematic review and meta-analysis.
This systematic review and meta-analysis examined changes in objective and subjective memory after electroconvulsive therapy (ECT) for major depressive episodes.
Measuring impulsivity differently yields different answers: A three-level meta-analysis of associations between impulsivity and adolescent non-suicidal self-injury.
This three-level random-effects meta-analysis examined associations between impulsivity and non-suicidal self-injury (NSSI) in adolescents, synthesising 37 studies (N = 69,572).
Haloperidol for Hypoactive and Hyperactive Delirium in ICU Patients-A Post Hoc Bayesian Analysis of the AID-ICU Trial.
This post hoc analysis of the AID-ICU trial evaluated the effects of haloperidol on delirium subtypes in 987 ICU patients. Haloperidol was linked to more days alive out of hospital, with a 76.5% probability of greater…
Psychiatric manifestation of neurosarcoidosis: a systematic review with pooled descriptive analysis of case reports and case series.
Neurosarcoidosis is a rare inflammatory disease with a heterogeneous presentation. Psychiatric manifestations may precede neurological involvement, but their prevalence, diagnostic pattern, and treatment outcomes remain…
Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles as a cell-free approach in autism spectrum disorder: A systematic review and meta-analysis of preclinical studies.
This systematic review and meta-analysis evaluated the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) in preclinical models of Autism Spectrum Disorder (ASD).
Efficacy and safety of noninvasive brain stimulation for ADHD: a systematic review and meta-analysis of double-blind randomized controlled trials across international English and Chinese databases.
This systematic review and meta-analysis examined double-blind, parallel-group randomised trials of noninvasive brain stimulation (NIBS) for clinical ADHD symptoms, including studies from China.
Anterior cingulate GABA and functional connectivity associated with initial treatment response in first-episode schizophrenia.
This randomized study examined whether anterior cingulate cortex (ACC) GABA levels and functional connectivity were associated with initial antipsychotic response in 87 people with first-episode schizophrenia.
Good morning or good evening: Daytime and cortisol as modulators of exposure therapy outcomes.
This double-blind randomized controlled trial examined whether treatment time and endogenous cortisol were associated with outcomes of group exposure therapy in 53 participants with spider-phobia symptoms.
Distinguishing bipolar disorder from unipolar depression in general practice: A systematic review.
This systematic review examined clinical and historical features that aid in distinguishing bipolar disorder from unipolar depression in general practice.
Rechallenge after Clozapine-Induced Neutropenic Events: A Case Series.
This case series discusses 13 patients who were rechallenged with clozapine after experiencing neutropenic events. The majority, 61.5%, were successfully maintained on the medication without fatalities.
Olanzapine-Induced Rapid Weight Gain and Metabolic Disorders: A Case Series.
This case series highlights four patients who experienced rapid and significant weight gain while on olanzapine, with three developing new-onset metabolic syndrome.
Gabapentin-Induced Severe Vivid Nightmares: A Case Series and Brief Review.
Two patients treated with gabapentin for spinal pain syndromes developed severe vivid nightmares, an underreported psychiatric side effect.
Peripheral Inflammatory Biomarkers as Predictors of Antidepressant Treatment Response in Major Depressive Disorder: An Updated Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the role of peripheral inflammatory biomarkers in predicting antidepressant response in adults with major depressive disorder (MDD).
Mindfulness-based and mindfulness-informed interventions for internet use disorders in adolescents and young adults: A three-level random-effects meta-analysis.
This systematic review and three-level random-effects meta-analysis assessed mindfulness-based and mindfulness-informed interventions (MBIIs) for internet use disorders in adolescents and young adults.
A smartphone-based serious game to improve mental health and medication adherence in adults with depression: A randomised controlled trial.
This randomised controlled trial tested a 9-week digital intervention in 148 adults receiving antidepressants who had residual depressive symptoms.
Fine-Tuning, Retrieval-Augmented Generation, and Hybrid Adaptation of Language Models for Clinical Decision-Making in Health Care: Systematic Review.
This systematic review evaluated the effectiveness of fine-tuning, retrieval-augmented generation (RAG), and hybrid adaptation strategies for transformer-based language models in clinical decision-making.
Improving Cardiometabolic Health in Adolescent Girls With Elevated Anxiety: Web-Based Multisite, Pilot, and Feasibility Randomized Controlled Trial.
This pilot randomized controlled trial evaluated the feasibility and acceptability of web-based interpersonal psychotherapy (IPT) and cognitive behavioral therapy (CBT) in adolescent girls aged 12-17 with elevated…
Prevalence of neuropsychiatric and seizure disorders in neurofibromatosis type 1: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed the prevalence of neuropsychiatric and seizure disorders in patients with neurofibromatosis type 1 (NF1).
Mental health burden among survivors of sexual-exploitation trafficking: a global systematic review, meta-analysis, and meta-regression.
This systematic review and meta-analysis examined the mental health burden among survivors of sexual exploitation trafficking, analyzing 18 studies.
Efficacy of A Virtual Agent-Based Digital Intervention (Echo App V2.0) for Patients With Alcohol Use Disorder: Randomized Controlled Trial.
This randomized controlled trial evaluated the Echo App V2.0, a virtual agent-based digital intervention, in 93 patients with alcohol use disorder (AUD).
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