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196 articles
April 20268
Baseline Interleukin-10 Levels as a Predictive Biomarker for Achieving Clinical Response With Abatacept in Patients Who Were Disease-Modifying Antirheumatic Drug Naive and Anti-Citrullinated Protein Antibody Positive With Early Rheumatoid Arthritis.
This post hoc analysis of the AVERT-2 phase III trial evaluated the predictive value of inflammatory biomarkers in patients with early rheumatoid arthritis (RA) who were naive to disease-modifying antirheumatic drugs.
The relationship between digit ratio (2D:4D) and autoimmune diseases: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the relationship between the second-to-fourth digit ratio (2D:4D) and autoimmune diseases (AIDs) in a population of 6958 patients.
Effects of locally applied water-filtered infrared a irradiation adjunctive to iloprost and carbon dioxide hand baths in patients with systemic sclerosis and severe Raynaud's phenomenon - a randomized controlled trial.
This randomized controlled trial assessed whether water-filtered infrared-A (wIRA) added to iloprost and carbon dioxide hand baths improved severe Raynaud’s phenomenon in patients with systemic sclerosis.
Lower Positive Body Pressure Walking Significantly Improves Pain and Function In Individuals With Knee Osteoarthritis: A Pilot Randomized Clinical Trial.
This parallel-group pilot randomized clinical trial evaluated body weight-supported walking in 49 adults aged over 50 with knee osteoarthritis, assigned to control, aquatic walking, or lower-body positive pressure…
Effectiveness of a Biopsychosocial-Based Exercise Approach Delivered in Group and Individual Formats in Primary Sjögren Disease: A Randomized Controlled Trial.
This three-arm, parallel, single-blind randomized controlled trial evaluated a biopsychosocial exercise approach (BETY) in 60 individuals with primary Sjögren disease.
Subsets of Patients With Lupus Identified by Gene Expression Profiles Exhibit Differential Clinical Responsiveness to Baricitinib.
This phase 2 randomised controlled trial analysis examined whether baseline gene-expression profiles could identify patients with systemic lupus erythematosus (SLE) who respond to baricitinib.
Risk of Retinopathy Associated with Long-Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined hydroxychloroquine retinopathy (HCQ-R) prevalence, cumulative incidence, and risk factors in adults with rheumatic diseases receiving long-term…
Transcranial Color-Coded Duplex Sonography in Large-Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report.
A 50-year-old woman with progressive large-vessel disease and sequential intracranial occlusions underwent multidisciplinary evaluation, which considered Takayasu arteritis the most likely diagnosis.
March 20264
Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial.
This phase 3b, randomized, 52-week trial compared ixekizumab plus tirzepatide with ixekizumab alone in adults with active psoriatic arthritis and overweight with a weight-related comorbidity or obesity.
New-onset of polymyalgia rheumatica in an elderly patient with calcium pyrophosphate deposition (CPPD) disease.
An 87-year-old woman presented with fever and knee pain. Calcium pyrophosphate crystals in synovial fluid supported a diagnosis of CPPD disease, and NSAIDs resolved her knee arthritis and inflammatory signs.
Severe systemic lupus erythematosus with thrombotic microangiopathy: rescue therapy with pegcetacoplan.
A 12-year-old girl with severe lupus nephritis and refractory thrombotic microangiopathy remained dialysis-dependent for several months despite intensive immunosuppression, including terminal complement blockade with…
Therapeutic effects of Xianlinggubao capsules on knee function, inflammatory response, and bone metabolism in elderly patients with degenerative knee osteoarthritis.
This randomised controlled trial evaluated Xianlinggubao (XLGB) capsules added to celecoxib in 100 elderly patients with degenerative knee osteoarthritis.
February 20266
Systematic Review and Meta-Analysis for JCS 2026 Guideline on Management of Large-Vessel Vasculitis.
This systematic review and meta-analysis assessed randomized controlled trial evidence for treatments of Takayasu arteritis (TAK) and giant cell arteritis (GCA), to inform the 2026 Japanese Circulation Society…
Atypical Cogan's Syndrome Is Common among Japanese Patients: A Case Report and Literature Review in Japan.
A 55-year-old Japanese woman presented with fever, headache, vertigo, sensorineural hearing loss, and scleritis. These findings led to a diagnosis of Cogan’s syndrome.
Temporomandibular joint ankylosis associated with psoriasis and familial Mediterranean fever: a rare case report.
A 40-year-old woman with psoriasis and familial Mediterranean fever developed progressive restriction of mouth opening. Clinical examination and imaging confirmed fibrous ankylosis of the right temporomandibular joint.
Utilization of Rehabilitation Services Among People With Common Autoimmune Rheumatic Diseases: A Systematic Review.
This systematic review assessed rehabilitation-service use among people with common autoimmune rheumatic diseases (ARDs), drawing on studies identified in PubMed and CINAHL through December 2023.
Macrophage Activation Syndrome Associated with Adult-onset Still's Disease Successfully Treated with Plasma Exchange and Canakinumab.
A 20-year-old Japanese woman with adult-onset Still’s disease developed macrophage activation syndrome despite prednisolone and tocilizumab.
Anti-citrullinated Protein Antibody-positive Arthralgia Associated with an L110P-E148Q Double Heterozygote: A Case-based Review.
A 42-year-old woman had arthralgia with positive anti-citrullinated protein antibodies and rheumatoid factor but did not initially meet criteria for rheumatoid arthritis.
January 20266
Concurrent Thyroid Tumor in an Elderly Patient with Giant Cell Arteritis: A Case Report.
An 85-year-old woman presented with abrupt fever, occipital headache, and proximal muscle pain. Despite no temporal artery tenderness or dilatation, 18F-FDG PET/CT showed uptake in bilateral vertebral and subclavian…
No significant short-term advantages of corticosteroids-augmented intra-articular injections of hyaluronic acid for knee osteoarthritis : A meta-analysis.
This meta-analysis of head-to-head randomised controlled trials compared intra-articular hyaluronic acid (HA) alone with HA augmented by corticosteroids in patients with knee osteoarthritis.
Prolonged remission of dermatomyositis and autoantibody negativization following SARS-CoV-2 infection in an elderly patient.
An 80-year-old patient with dermatomyositis diagnosed in 2014 had initially responded to methotrexate. After severe SARS-CoV-2 infection with significant pulmonary involvement in March 2022, methotrexate was stopped.
Ozone injections reduce pain in knee osteoarthritis: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed intra-articular ozone injections versus corticosteroid injections for pain and function in people with knee osteoarthritis.
Longitudinal Immunophenotypic Changes in Refractory Lupus Nephritis After B-cell Depletion: A 25-year Case Study.
A woman diagnosed with systemic lupus erythematosus at age 25 developed biopsy-proven class IV lupus nephritis and entered a 20-year clinical remission after 12 cycles of intravenous cyclophosphamide.
Multisystem Burden of Paediatric Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis of Neuropsychiatric, Renal, Ocular, and Immunological Outcomes.
This systematic review and random-effects meta-analysis examined observational studies of children with systemic lupus erythematosus (pSLE) and quantified disease activity, assessing associations with multisystem…
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