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1316 articles
October 202624
Efficacy and safety of subcutaneous efgartigimod with prednisone in moderate-to-severe pemphigus (ADDRESS): a global, phase III, randomised controlled, double-blind trial.
ADDRESS was a global, phase III, multicentre, randomised, double-blind, placebo-controlled trial of adults with newly diagnosed or relapsing moderate-to-severe pemphigus.
Association of dietary choline intake with cognitive decline and related outcomes: a systematic review and dose-response meta-analysis of observational studies.
This systematic review and dose-response meta-analysis examined observational evidence on dietary choline intake and cognitive decline or related outcomes.
Technological Integration in Triage With AI and Machine Learning Compared With Conventional Triage and Narrative Synthesis of Telehealth for Patient Prioritization in Emergency and Acute Care Settings: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed AI- and machine-learning-assisted triage alongside tele-triage and digital tools in emergency and acute care.
Evaluating the impact of conditional micro-incentives on linkage to HIV care in rural South Africa: results from the Home-Based Intervention to Test and Start (HITS) trial.
The HITS real-world randomized trial assessed whether conditional food vouchers improved linkage to HIV care after home-based testing in rural KwaZulu-Natal, South Africa.
Walnut consumption improves mood and is associated with increased urinary excretion of 5-hydroxyindoleacetic acid and urolithins in a randomized crossover trial.
This 18-week open-label randomized crossover trial assessed whether daily walnut consumption affected mood and urinary metabolites in 31 healthy young adults.
Comparative efficacy of interventions for preventing chemotherapy-induced alopecia: a systematic review and network meta-analysis.
This systematic review and network meta-analysis compared preventive interventions for chemotherapy-induced alopecia in cancer patients, including 12 randomized trials with 736 participants and nine intervention groups.
POCUS Image Archiving in Emergency Medicine: A Systematic Review of Clinical and Financial Impacts.
This systematic review assessed clinical, operational, and financial outcomes of archiving point-of-care ultrasound (POCUS) images in electronic health records in emergency departments.
Clinical and functional outcomes of aquatic plyometrics in adolescent patellofemoral pain syndrome: a dual-arm randomized controlled trial.
This dual-arm randomized controlled trial compared aquatic plyometric exercises with conventional exercises in 56 adolescents aged 10–18 years with patellofemoral pain syndrome.
Tranexamic acid in laparoscopic sleeve gastrectomy: bleeding control amid thrombotic concerns and hemodynamic instability: a randomized double-blinded clinical trial.
This randomized, double-blinded clinical trial assessed tranexamic acid (TXA) for perioperative bleeding prevention in 185 patients with morbid obesity undergoing elective laparoscopic sleeve gastrectomy.
Effectiveness of digital educational technologies in knowledge acquisition for adolescent health promotion: a systematic review.
This systematic review assessed whether digital educational technologies improve health-promotion knowledge among adolescents.
Miro1 mediates skeletal muscle insulin resistance in type 2 diabetes.
This study investigated whether mitochondrial Rho GTPase 1 (Miro1) contributes to skeletal muscle insulin resistance in type 2 diabetes (T2D).
Daily consumption of unsalted, skin-roasted peanuts beneficially affects regional brain insulin responsiveness in older adults: results of a longer-term randomized controlled trial.
This randomized, single-blind, controlled crossover trial examined whether peanut intake altered brain insulin responsiveness in 31 older adults (67 ± 4 years).
Advances in physiotherapy for chronic low-back pain: a level I systematic review.
This level I systematic review qualitatively examined randomised controlled trials of physiotherapy programmes for chronic low-back pain (cLBP), identified through searches of PubMed, Web of Science and Embase in August…
The Impact of Anaesthesia Method on the Use of Anaesthesia Department Resources in Total Knee Arthroplasty.
This randomised controlled trial compared spinal anaesthesia with general anaesthesia using total intravenous anaesthesia in 395 patients undergoing total knee arthroplasty.
Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects.
This open-label, randomized, single-dose, three-period crossover study compared the pharmacokinetics and safety of 20 mg zastaprazan orally disintegrating tablets (ODTs), taken with or without water, with the…
Magnetic resonance imaging vs computed tomography for baseline imaging evaluation in acute basilar artery occlusion.
This post hoc analysis of the ATTENTION trial compared baseline MRI with CT for patient selection in acute basilar-artery occlusion.
Full-spectrum LED screen-bar lighting as an adjunct to artificial tears in visual display terminal-related dry eye: a randomized study.
This prospective, randomised, single-centre study assessed whether full-spectrum screen-bar lighting adds benefit to artificial tears in 66 participants with newly diagnosed visual display terminal-related dry eye and…
Microsurgical clipping versus Woven EndoBridge embolization for intracranial aneurysms: a systematic review and meta-analysis.
This systematic review and meta-analysis compared microsurgical clipping with Woven EndoBridge (WEB) embolization for ruptured and unruptured intracranial aneurysms.
Switching from Intravenous to Subcutaneous Infliximab in Children with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis synthesized six independent, largely observational cohorts of children with inflammatory bowel disease who switched from intravenous to subcutaneous infliximab (n = 173).
Gamma-irradiated amniotic membrane graft as an adjuvant to posterior colporrhaphy: an exploratory prospective single-arm clinical trial.
This exploratory prospective, single-arm pilot clinical trial evaluated gamma-irradiated amniotic membrane grafting during posterior colporrhaphy in 25 women with posterior compartment prolapse.
PD-1/ PD-l1 Inhibitors and Stereotactic Radiosurgery for Brain Metastases: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed efficacy and toxicity when PD-1/PD-L1 inhibitors were combined with stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) for…
Duration of single-agent perioperative antibiotic prophylaxis and postoperative meningitis after endoscopic endonasal skull base surgery: a systematic review and meta-analysis of 7,981 patients.
This systematic review and meta-analysis examined postoperative meningitis after endoscopic endonasal skull-base surgery in 7,981 patients across 14 studies using single-agent perioperative antibiotic prophylaxis.
Gene-based association analysis of depression risk among European ancestry Parkinson's disease patients.
This gene-based association analysis and meta-analysis examined common and low-frequency genetic variants related to depression among European-ancestry patients with Parkinson’s disease (PD) in three population-based…
Symptom duration and postoperative outcomes in degenerative cervical myelopathy: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether symptom duration is associated with outcomes after surgery for degenerative cervical myelopathy (DCM).
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