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1998 articles
October 202624
Exertional Rhabdomyolysis With Moderate Creatine Kinase Elevation and Marked Transaminase Elevation but Preserved Synthetic Function: A Case Report.
A 43-year-old man presented with fatigue, nausea, and myalgia following a 3000-m run. Laboratory tests revealed moderate creatine kinase (CK) elevation at 2828 U/L alongside significantly elevated transaminases: AST at…
Robot-assisted versus non-robotic partial nephrectomy for completely endophytic renal tumors: a systematic review and meta-analysis.
This systematic review and meta-analysis compared robot-assisted partial nephrectomy (RAPN) with laparoscopic (LPN) and open partial nephrectomy (OPN) for completely endophytic renal tumors (CERTs) in 896 patients.
Vitamin D Supplementation and Mortality in the Elderly: A Review of a Meta-Analysis of Randomized Controlled Trials Using the REB Method.
This meta-analysis reviewed 25 randomized controlled trials (RCTs) to evaluate the impact of vitamin D supplementation on mortality in individuals aged 75 and older.
Learning curves in robotic and laparoscopic colorectal surgery: a systematic review.
This systematic review evaluated learning curves in laparoscopic and robotic colorectal surgery, analyzing 114 studies with 167 learning-curve analyses.
Concordance of Microbiological and Histopathological Examination of Bone Biopsies in Diagnosing Diabetic Foot Osteomyelitis, a Systematic Review.
This systematic review evaluated the diagnostic concordance of histopathology and microbiology in bone biopsies from 308 adults with diabetic foot osteomyelitis (DFO).
Determinants of delayed antenatal visit attendance in rural Burkina Faso: a cross-sectional study.
This cross-sectional study assessed delayed antenatal care (ANC) attendance among pregnant women in rural Burkina Faso. Out of 2480 women with data, 90.6% attended their first ANC visit after the 14th week of gestation.
HD-tACS at 40 Hz improves consciousness and brain connectivity in prolonged disorders of consciousness: a randomized sham-controlled clinical trial.
This randomized, sham-controlled clinical trial evaluated 40 Hz and 4 Hz high-definition transcranial alternating current stimulation (HD-tACS) in 60 patients with prolonged disorders of consciousness.
Spinal Muscular Atrophy.
This article reviews the history, epidemiology, genetics, clinical presentation, multidisciplinary management, and established and emerging therapies for patients with spinal muscular atrophy.
Hypofractionated 44 Gy in 20 fractions versus conventional chemoradiation in cervical cancer: 2-year results of the randomized HYPOCx-iRex trial with an exploratory pooled analysis of a single-institute EMBRACE-II cohort.
The randomized HYPOCx-iRex trial compared hypofractionated chemoradiation (44 Gy in 20 fractions) with conventional chemoradiation (45 Gy in 25 fractions) for locally advanced cervical cancer; an exploratory pooled…
Impact of digital health interventions in improving pediatric immunization coverage and timeliness in low- and middle-income countries: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed randomized controlled trials of digital interventions to improve pediatric vaccination outcomes in low- and middle-income countries.
Rapid manufactured CAR-T cells enriched for CD45RA-negative T cells exhibit superior persistence compared to conventional CAR-T therapy.
This comparative study evaluated InstanCAR-T, a rapid CD19 CAR-T manufacturing protocol enriched for CD45RA-negative T cells, against conventional CAR-T in laboratory assays, murine B-ALL models, and a Phase I clinical…
Guillain-Barré Syndrome.
This article reviews the epidemiology, clinical symptoms, examination findings, pathogenesis, diagnostic criteria, and recent guidelines of Guillain-Barré syndrome (GBS) and its variants, including information on…
Comparison of Molecular Methods With Culture for Identifying Microbial Etiology in Pediatric Empyema Thoracis: A Systematic Review of Diagnostic Test Accuracy.
This systematic review evaluated the diagnostic accuracy of molecular methods versus culture for identifying microbial etiology in pediatric empyema thoracis.
Comparisons in Analgesic Effects Between Ultrasound-Guided Erector Spinae Plane Block and Ultrasound-Guided Modified Intercostal Nerve Block in Modified Radical Mastectomy: A Randomized Controlled Trial.
Postoperative acute pain is a common challenge after breast cancer surgery. This randomized controlled trial compared the analgesic effects of ultrasound-guided erector spinae plane block (ESPB) and modified intercostal…
Nutritional and Toxic Neuropathies.
This article reviews the etiologies, clinical presentations, and management of nutritional and toxic neuropathies.
Wellness and Career Sustainability in Neurology.
This article reviews drivers of well-being in neurology, using the practice of neuromuscular neurology as an example and high-yield interventions to enhance professional fulfillment.
Native collagen matrix plus PHMB antimicrobial in hard-to-heal diabetic foot ulcers: results from the PREPARE randomised controlled trial.
The PREPARE prospective, multicentre randomised controlled trial compared purified native type 1 collagen extracellular matrix plus polyhexamethylene biguanide (PCMP) with standard care (SoC) alone in patients with…
Intraoperative Dexmedetomidine and Postoperative Delirium After Head and Neck Cancer Surgery with Free-Flap Reconstruction: A Secondary Analysis of a Randomized Placebo-Controlled Trial.
This delirium-focused secondary analysis of a single-centre, randomized, double-blind, placebo-controlled trial examined adults undergoing elective head and neck cancer surgery with free-flap reconstruction.
Markedly Elevated CA 19-9 in Type I Mirizzi Syndrome in the Absence of Malignancy: A Case Report.
A 50-year-old man presented with acute obstructive jaundice, fever, and right upper quadrant pain; serum CA 19-9 was 1000 U/mL.
Isolated Prostatic Tuberculosis Coexisting with Benign Prostatic Hyperplasia: A Case Report.
A 70-year-old man presented with one month of lower urinary tract symptoms and recurrent urinary retention requiring repeated catheterization.
Non-Ischemic Cerebral Enhancing (NICE) lesions after flow diversion for intracranial aneurysms: a systematic review with case-level synthesis.
This PROSPERO-registered systematic review synthesized reports of delayed non-ischemic cerebral enhancing (NICE) lesions after flow-diverter treatment of intracranial aneurysms; heterogeneity precluded meta-analysis.
Clinical outcomes of early versus standard liver transplantation in patients with alcohol-related liver disease: a meta-analysis.
This meta-analysis compared early and standard liver transplantation in patients with alcohol-related liver disease. It included 12 studies and 2323 patients.
Small Fiber Neuropathy.
Small fiber neuropathy is a common disorder; however, its diagnosis and treatment can be challenging. This article outlines the pain pathways involved in small fiber neuropathy and provides an overview of its various…
Facilitators of Peer Support Among Patients With Chronic Kidney Disease: A Systematic Review and Qualitative Meta-Synthesis.
This systematic review and qualitative meta-synthesis examined facilitators of peer support among patients with chronic kidney disease (CKD).
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