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1998 articles

October 202624

Case ReportNeurologyOpen access

Bobble-Head Doll Syndrome Caused by Aqueductal Web-Associated Obstructive Hydrocephalus in an Adult: A Case Report with Video.

A 24-year-old man developed progressive memory impairment, gait instability, urinary incontinence, and an irregular side-to-side (“no-no”) head tremor that improved with a sensory trick.

Tremor Other Hyperkinet Mov (N Y)Oct 8, 2026Read case
Case ReportPediatrics

68Ga-DOTATATE PET/CT Detection of Hypertrophic Osteoarthropathy in a Pediatric Patient With Neuroblastoma Following Anti-GD2 Immunotherapy.

A 5-year-old boy with high-risk neuroblastoma underwent 68Ga-DOTATATE PET/CT to assess response after anti-GD2 immunotherapy.

Clin Nucl MedOct 8, 2026Read case
Clinical ResearchInternal Medicine (General)

Real-World Effectiveness of AI-Enabled Clinical Decision Support in Primary Care: Systematic Review.

This systematic review synthesized real-world evaluations of clinician-facing AI-enabled clinical decision support in primary and ambulatory care, covering studies published from 2011 through 2025.

J Med Internet ResOct 8, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Comparison of two repetitive peripheral magnetic stimulation protocols for upper trapezius myofascial pain syndrome: A randomized trial.

This single-centre, assessor-blinded randomized trial compared 10- and 15-minute repetitive peripheral magnetic stimulation (rPMS) protocols, each given weekly for 4 weeks alongside stretching, in adults aged 18–55 with…

PLoS OneOct 8, 2026Read summary
Case ReportGeneral Surgery

Perioperative Nursing Care of a Patient With 70% TBSA Second- To Third-Degree Flame Burns Complicated by Pseudomonas aeruginosa Infection: A Case Report.

A patient with 70% TBSA second- to third-degree flame burns developed a Pseudomonas aeruginosa infection and required surgical care, including back debridement.

Nurs Crit CareOct 8, 2026Read case
Case ReportNeurologyOpen access

Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature.

A 52-year-old woman presented with positional vertigo and was initially diagnosed with right superior semicircular canal benign paroxysmal positional vertigo (BPPV).

J Med Case RepOct 7, 2026Read case
Clinical ResearchRheumatology

Prospective controlled study of the recombinant zoster vaccine in autoimmune rheumatic disease: robust seroconversion despite intravenous cyclophosphamide.

This subanalysis of a prospective, randomized, placebo-controlled trial assessed recombinant zoster vaccine (RZV) responses in patients with autoimmune rheumatic disease receiving intravenous cyclophosphamide (IVCYC)…

VaccineOct 7, 2026Read summary
Clinical ResearchOncology (Medical)

Chemotherapy backbone and outcomes of immune checkpoint inhibitor combinations across solid tumors: a pan-tumor network meta-analysis.

This systematic review and network meta-analysis examined phase II–III randomised trials comparing first-line immune checkpoint inhibitor (ICI) plus chemotherapy with chemotherapy alone across solid tumours, assessing…

OncologistOct 7, 2026Read summary
Clinical ResearchDermatology

Acrokeratosis paraneoplastica (Bazex syndrome): a systematic review and quantitative analysis of 106 cases.

Acrokeratosis paraneoplastica (Bazex syndrome) is an obligate paraneoplastic dermatosis characterized by symmetrical acral psoriasiform lesions and nail dystrophy.

OncologistOct 7, 2026Read summary
Clinical ResearchOncology (Medical)

Dose response relationship of medical cannabis and symptom control in patients with pancreatic cancer: an analysis of the CANPAN trial.

This analysis of the CANPAN pilot waitlist-control randomized trial examined cannabis use, patient-reported outcome completion, and THC dose-response among 32 cannabis-naïve patients with newly diagnosed locally…

OncologistOct 7, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Survival outcomes following total intravenous versus volatile anesthesia in esophagogastric cancer surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis compared total intravenous anesthesia (TIVA) with volatile anesthesia in adults undergoing curative surgery for esophageal or gastric cancer.

Langenbecks Arch SurgOct 7, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Efficacy of direct-acting antiviral regimens for acute HCV infection: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed interferon-free dual direct-acting antiviral regimens for acute or recently acquired HCV infection.

Virol JOct 7, 2026Read summary
Clinical ResearchPsychiatryOpen access

Anxiety and Depression in Athletes of Different Levels Without Current Injury: A Systematic Review With Meta-Analyses.

This systematic review and random-effects meta-analysis examined anxiety and depression in athletes across competitive levels, including those without current injury.

J Athl TrainOct 7, 2026Read summary
Clinical ResearchPediatricsOpen access

Short- versus long-course antibiotic therapy in non-severe CAP in children: a systematic review and meta-analysis.

This systematic review and meta-analysis compared short-course (≤ 5 days) with longer (> 5 days) antibiotic therapy for non-severe community-acquired pneumonia in immunocompetent children.

Eur J PediatrOct 7, 2026Read summary
Clinical ResearchInfectious Diseases

Safety and Immunogenicity of the Live-Attenuated Quadrivalent Dengue Vaccine V181 Compared With Butantan-DV Among Healthy Adults in Brazil: A Randomized, Double-Blind, Phase 2 Trial.

This randomized, double-blind, active-comparator phase 2 trial compared the safety and immunogenicity of single-dose quadrivalent dengue vaccines V181 and Butantan-DV in healthy adults in Brazil.

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchInfectious Diseases

Safety, Efficacy, and Immunogenicity of a Multivalent Adjuvanted Staphylococcus aureus Vaccine in Adults With Recent Skin and Soft Tissue Infections: An Observer-Blind, Randomized, Placebo-Controlled, Multinational Phase 1/2 Trial.

This observer-blind, randomized, placebo-controlled phase 1/2 trial evaluated a five-antigen Staphylococcus aureus vaccine with AS01E adjuvant in adults, including 194 participants aged 18–64 years with a recent S.

Clin Infect DisOct 7, 2026Read summary
Case ReportOphthalmology

Time to improve laboratory protocols in microbial keratitis: broad-range Internal Transcribed Spacer sequencing in refractory culture-negative keratitis.

A woman in her 60s who wore soft contact lenses developed rapidly progressive microbial keratitis that did not respond to intensive empirical treatment.

BMJ Case RepOct 7, 2026Read case
Case ReportHematology

Successful treatment of hairy cell leukemia with TP53 abnormality using cladribine combined with low-dose rituximab: a case report and literature review.

An elderly man with classical hairy cell leukemia (HCL) had BRAF V600E positivity, a TP53 deletion detected by fluorescence in situ hybridization, and bone marrow fibrosis.

Anticancer DrugsOct 7, 2026Read case
Case ReportOncology (Medical)

Case report: successful use of repotrectinib in a ROS1 fusion-positive lung adenocarcinoma patient with severe renal insufficiency and prior tyrosine kinase inhibitor treatment failure.

A 69-year-old woman with advanced lung adenocarcinoma harboring an SDC4–ROS1 fusion had bilateral pulmonary lesions, mediastinal lymphadenopathy, and pleural effusions.

Anticancer DrugsOct 7, 2026Read case
Case ReportNeurologyOpen access

Multiple Sclerosis During Pregnancy and the Postpartum Period: Diagnostic and Multidisciplinary Challenges in Two Cases.

The report describes two pregnant women with progressive focal neurological symptoms and brain MRI abnormalities concerning for central nervous system demyelination.

Int Med Case Rep JOct 7, 2026Read case
Clinical ResearchInfectious Diseases

Fosfomycin as Oral Transition Therapy Versus Continued Intravenous β-Lactams for Complicated Urinary Tract Infections Caused by Extended-Spectrum β-Lactamase-Producing Enterobacterales: A Multicenter, Open-Label, Randomized Controlled Trial.

This multicenter, open-label randomized noninferiority trial compared oral fosfomycin transition therapy with continued intravenous carbapenem or β-lactam/β-lactamase inhibitor therapy in hospitalized adults with…

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchInfectious Diseases

Multidimensional Poverty and Implementation Reach of Household Contact Tracing for Tuberculosis in South Africa: Analysis of a Randomized Trial.

This analysis of a cluster-randomized trial in South Africa examined whether household multidimensional poverty was associated with the reach of household contact tracing (HHCT) for tuberculosis.

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchInfectious Diseases

HIV care cascade of adolescents and young adults in sub-Saharan Africa: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed progress toward the UNAIDS 95-95-95 targets among adolescents and young adults living with HIV in sub-Saharan Africa. It included 37 studies from 13 countries.

BMJ OpenOct 7, 2026Read summary
Clinical ResearchOncology (Medical)

Sunitinib in Patients With Various Solid Tumors With FGFR1 / 2 Alterations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.

This phase II basket trial evaluated sunitinib in patients with advanced solid tumours and FGFR1 or FGFR2 alterations who had no remaining standard treatment options. Histology-specific cohorts were pooled by alteration.

JCO Precis OncolOct 7, 2026Read summary

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