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1998 articles
October 202624
MRD negativity by PBMCs and ctDNA confirms deep and durable responses after epcoritamab monotherapy in R/R FL.
The EPCORE NHL-1 trial evaluated the efficacy of epcoritamab, a CD3 × CD20 bispecific antibody, in patients with relapsed/refractory follicular lymphoma (FL) after at least two prior therapies.
Regional practice differences significantly affect the benefit of post-HCT gilteritinib in FLT3-ITD AML.
The phase 3 MORPHO trial evaluated the efficacy of gilteritinib versus placebo in post-hematopoietic cell transplantation (HCT) for FLT3-ITD AML patients.
Postnatal interventions to support newborn survival: updates for the Lives Saved Tool.
This systematic review evaluated postnatal interventions aimed at reducing neonatal mortality, particularly in low- and middle-income countries.
Facilitators of Peer Support Among Patients With Chronic Kidney Disease: A Systematic Review and Qualitative Meta-Synthesis.
This systematic review and qualitative meta-synthesis examined facilitators of peer support among patients with chronic kidney disease (CKD).
Effects of SGLT-2 Inhibitors on Plasma Concentrations and Renal Clearance of the Risk Marker Trimethylamine-N-Oxide in Patients With Type-2 Diabetes.
This randomized controlled trial investigated the effects of SGLT-2 inhibitors empagliflozin and dapagliflozin on plasma levels and renal clearance of trimethylamine-N-oxide (TMAO) in patients with Type 2 diabetes.
Efficacy and Safety of Oral Non-Statin Lipid-Lowering Therapies in Dyslipidaemia: A Systematic Review and Network Meta-Analysis.
This systematic review and network meta-analysis evaluated the efficacy and safety of oral non-statin lipid-lowering therapies in adults with dyslipidaemia.
Small Fiber Neuropathy.
Small fiber neuropathy is a common disorder; however, its diagnosis and treatment can be challenging. This article outlines the pain pathways involved in small fiber neuropathy and provides an overview of its various…
Platelet-rich plasma versus corticosteroid injections for facet and sacroiliac joint pain: a systematic review and meta-analysis with trial sequential analysis.
This systematic review and meta-analysis evaluated the efficacy of platelet-rich plasma (PRP) versus corticosteroid injections for treating facet and sacroiliac joint pain in 392 patients.
Family-Centered Child Obesity Treatment: The TEAM UP Randomized Clinical Trial.
This pragmatic randomized clinical trial evaluated the effectiveness of enhanced standard of care with family-based behavioral treatment (ESOC+FBT) compared to enhanced standard of care alone (ESOC) in reducing percent…
A Phase 2, Open-Label, Randomized Controlled Trial Evaluating Safety and Efficacy of Dose-Intensified Versus Standard Dosing Regimens of [ 177 Lu]Lu-PSMA-597 in mCRPC (OPTIMAL-PSMA).
The OPTIMAL-PSMA study is a Phase 2, open-label, randomized controlled trial evaluating the safety and efficacy of a dose-intensified regimen of [177Lu]Lu-PSMA-597 versus standard dosing in 120 patients with metastatic…
Erythropoietin for Neonatal Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.
This multicenter randomized clinical trial evaluated the efficacy of erythropoietin (EPO) as an adjunct to therapeutic hypothermia in infants with moderate to severe hypoxic-ischemic encephalopathy (HIE).
Treatment of Multifood Allergy With Omalizumab or Multiallergen Oral Immunotherapy: A Randomized Clinical Trial.
This randomized clinical trial compared the efficacy of omalizumab versus multiallergen oral immunotherapy (MOIT) in treating multifood allergies in participants aged 1 to 55 years.
A double-blind multi-centre randomised placebo-controlled trial of doxycycline in women with recurrent miscarriage and chronic endometritis defined by CD138 positive stromal cells.
This multicenter, double-blind, randomized controlled trial evaluated the effect of preconceptual doxycycline on live birth rates in women with recurrent miscarriage and chronic endometritis defined by CD138 positive…
Health Communication and Stepped Reminders Interventions for Lung Cancer Screening: A Randomized Clinical Trial.
This randomized clinical trial evaluated two patient-centered interventions aimed at increasing adherence to annual lung cancer screening among patients with normal findings.
The impact of unilateral endometriomas on ovarian response to stimulation: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the impact of unoperated unilateral endometriomas on ovarian response during stimulation cycles in women with endometriosis.
Autonomous Oxygen Titration for Maintaining Normoxemia in Acutely Ill Adults: The SAVE-O2 AI Randomized Clinical Trial.
The SAVE-O2 AI randomized clinical trial evaluated the effectiveness of autonomous oxygen titration in maintaining normoxemia in acutely ill adults receiving supplemental oxygen.
Histological Analysis Shows That a Moisturizer Formulated for Dermatoporosis Increases Elastin Content and Improves Skin Elasticity.
This multicenter clinical trial evaluated the effects of a novel moisturizer (GC cream) on skin biomarkers in individuals aged 40 to 60 with dermatoporosis.
Disseminated Bartonella or Post-Transplant Lymphoproliferative Disease in Pediatric Transplant Patients: A Diagnostic Challenge.
A pediatric kidney transplant patient presented with fever, lymphadenopathy, nausea, vomiting, and abdominal pain. An extensive workup for post-transplant lymphoproliferative disease (PTLD) was initiated, including PET…
Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence.
Two patients with chronic limb-threatening ischemia (CLTI) undergoing maintenance hemodialysis received concomitant Rheocarna therapy.
Effect of Skin-To-Skin Contact During Caesarean Section on Pain and Stress in Newborns: A Randomized Controlled Trial.
This randomized controlled trial evaluated the impact of skin-to-skin contact during caesarean sections on neonatal pain and stress during the first intramuscular injection.
A Case of Primary Intramedullary Infantile Fibrosarcoma With an RBPMS::NTRK3 Fusion and Response to Larotrectinib.
A 4-week-old infant presented with rapidly progressive cervical myelopathy due to primary intramedullary infantile fibrosarcoma.
Bone Accrual During Puberty Suppression and Gender-Affirming Therapy in Transgender Adolescents: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated bone mineral density (BMD) and z scores in transgender adolescents undergoing gonadotropin-releasing hormone agonist (GnRHa) therapy followed by gender-affirming…
Balloon Enteroscopy-Assisted ERCP and EUS-Guided Biliary Drainage for Malignant Biliary Obstruction in Patients With Surgically Altered Anatomy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed balloon enteroscopy-assisted ERCP (BEA-ERCP) versus EUS-guided biliary drainage (EUS-BD) for malignant biliary obstruction in patients with surgically altered anatomy.
Evolving Fetal Biometry in Fetal Intrahepatic Portosystemic Shunt With Late-Onset Preeclampsia and Focal Umbilical Cord Hypercoiling: A Case Report.
A pregnancy was evaluated at 26 + 3 weeks for suspected severe early-onset fetal growth restriction, with fetal weight below the 1st percentile. Imaging revealed a fetal intrahepatic portosystemic shunt.
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