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1998 articles

October 202624

Case ReportMedical Genetics

Pediatric Spinal Cord Astrocytoma With Granular Cell-Like Morphology and KIAA1549::BRAF Fusion.

A pediatric patient presented with a spinal cord tumor exhibiting prominent granular cell-like features, complicating the initial diagnosis.

NeuropathologyOct 1, 2026Read case
Clinical ResearchHematology

Lenalidomide-Related Diarrhea in Patients with Multiple Myeloma Is Associated with Gut Microbiota Dysbiosis and Disruption of the Bile Acid Pool.

This Phase II randomized controlled trial investigated the relationship between gut microbiota dysbiosis, bile acid pool disruption, and lenalidomide-related diarrhea (LRD) in patients with multiple myeloma.

Clin Cancer ResOct 1, 2026Read summary
Clinical ResearchCardiology

Efficacy and Safety of Lorundrostat for Uncontrolled and Treatment-resistant Hypertension: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the efficacy and safety of lorundrostat in adults with uncontrolled or treatment-resistant hypertension.

J Cardiovasc PharmacolOct 1, 2026Read summary
Clinical ResearchCardiology

Prednisone in the Management of Pericarditis: A Systematic Review.

This systematic review evaluated the use of oral corticosteroids, primarily prednisone, in adults with acute or recurrent pericarditis.

J Cardiovasc PharmacolOct 1, 2026Read summary
Clinical ResearchCardiology

Efficacy and Safety of CETP Inhibitors in Patients With Atherosclerotic Cardiovascular Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the efficacy and safety of cholesteryl ester transfer protein (CETP) inhibitors in 62,565 patients with atherosclerotic cardiovascular disease.

J Cardiovasc PharmacolOct 1, 2026Read summary
Case ReportHematology

Spontaneous splenic rupture in a patient with congenital factor XIII deficiency: A case report and literature review.

A 32-year-old man with congenital factor XIII deficiency presented with sudden abdominal pain and hypovolemic shock. Contrast-enhanced abdominal CT showed a large perisplenic hematoma, and surgery confirmed splenic…

Ulus Travma Acil Cerrahi DergOct 1, 2026Read case
Clinical ResearchEndocrinology

Effects of sprint interval training on markers of metabolic health: A three-level meta-analysis of randomised controlled trials.

This systematic review and three-level meta-analysis examined randomised controlled trials comparing sprint interval training (SIT) with no-exercise control or moderate-intensity continuous training (MICT) for metabolic…

J Sports SciOct 1, 2026Read summary
Clinical ResearchCardiologyOpen access

Diagnostic Accuracy of Circulating MicroRNAs for Coronary Artery Disease: An Updated Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic accuracy of circulating microRNAs (miRNAs) for coronary artery disease (CAD) in 3,879 participants across 24 studies.

J Cardiovasc Transl ResOct 1, 2026Read summary
Case ReportNeurosurgery

How I do it: meningioangiomatosis of the sylvian fissure. The need for a tailored functional neurosurgery.

A patient with drug-resistant epileptic seizures presented with meningioangiomatosis located in the right sylvian fissure, affecting the M1-M2 segments of the right middle cerebral artery.

Acta Neurochir (Wien)Oct 1, 2026Read case
Clinical ResearchOncology (Medical)Open access

Association of HRD Score With Efficacy of Neoadjuvant Short-Course Radiotherapy Plus Sequential Chemoimmunotherapy in pMMR Locally Advanced Rectal Cancer.

This Phase II clinical trial examined the relationship between homologous recombination deficiency (HRD) score and treatment response in 32 patients with mismatch repair-proficient locally advanced rectal cancer…

Cancer Rep (Hoboken)Oct 1, 2026Read summary
Clinical ResearchRheumatology

Effects of Yoga on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effects of yoga on psychological function and inflammation in individuals with rheumatoid arthritis (RA).

Int J Rheum DisOct 1, 2026Read summary
Clinical ResearchPsychiatry

Who is getting better in treatment? Dynamics in risk processes as a signature of short-term suicide treatment response.

This analysis of adults receiving up to 12 sessions of suicide-focused therapy within a randomized clinical trial examined whether weekly patterns in suicide risk and resilience differed according to suicide attempts…

J Affect DisordOct 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Factors affecting the experience of procedural and postoperative pain in children and adolescents - a systematic review.

This systematic review examined factors influencing procedural and postoperative pain in children and adolescents aged 3-18 years.

BMC Oral HealthOct 1, 2026Read summary
Case ReportUrology

Retroperitoneal urinoma presenting as a posterior knee sinus following emphysematous pyelitis.

A woman in her late 40s presented with abdominal sepsis due to emphysematous pyelitis and a retroperitoneal urinoma. Despite initial treatment, she developed persistent thigh pain and a posterior knee sinus.

BMJ Case RepOct 1, 2026Read case
Clinical ResearchGeriatricsOpen access

Factors influencing access to green health prescribing in primary care for older adults - a qualitative systematic review.

This systematic review examined barriers and enablers to green health prescribing (GHP) for older adults with long-term conditions.

BMC MedOct 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Evaluating plasma ferritin and suPAR as treatable traits for critically ill patients with COVID-19 treated with anakinra: an exploratory analysis of the immune modulation domain of the REMAP-CAP randomised clinical trial.

This exploratory analysis of the REMAP-CAP randomized clinical trial evaluated plasma ferritin and suPAR as potential treatable traits for anakinra in critically ill COVID-19 patients.

Crit CareOct 1, 2026Read summary
Case ReportDermatology

Use of a Synthetic Polylactic Acid Matrix for Pyoderma Gangrenosum: A Case Series.

This case series involved six patients with chronic, non-healing ulcers due to pyoderma gangrenosum, persisting for 6 months to 3 years.

Int Wound JOct 1, 2026Read case
Clinical ResearchGastroenterology

Opioid-Sparing Analgesia After Laparoscopic Gastrectomy: Exploratory Clinical Outcomes and Cine-MRI Assessment of Small-Bowel Motility.

This randomized controlled trial evaluated opioid-sparing multimodal analgesia versus conventional opioid analgesia in 130 patients undergoing laparoscopic radical gastrectomy.

J Vis ExpOct 1, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Portable Dynamometry Is Reliable for Measuring Knee and Ankle Strength in Daily Practice: Results From a Systematic Review With Meta-analysis and Evidence Gap Map Using the COSMIN Methodology.

This systematic review and meta-analysis evaluated the reliability and criterion validity of portable dynamometers for measuring knee and ankle muscle strength in both uninjured individuals and those with lower-limb…

J Orthop Sports Phys TherOct 1, 2026Read summary
Case ReportOrthopedic Surgery

Trauma-related simultaneous asymmetric bilateral hip dislocation: A case report.

A 27-year-old man sustained simultaneous dislocations of both hips after high-energy trauma: the left hip was anteriorly dislocated and the right posteriorly.

Ulus Travma Acil Cerrahi DergOct 1, 2026Read case
Clinical ResearchOncology (Medical)

[18F]RCCB6 PET/CT in Diagnosing Clear-Cell Renal Cell Carcinomas: A Prospective Comparison Study with [18F]FDG PET/CT and Conventional Imaging.

[18F]RCCB6 PET/CT was evaluated in a single-center phase II trial for detecting metastases in clear-cell renal cell carcinoma (ccRCC).

Cancer DiscovOct 1, 2026Read summary
Clinical ResearchEmergency Medicine

Evaluating CPR Breast Attachment Impact on EMT Training: A Randomized Controlled Trial.

This randomized controlled trial evaluated the impact of the ReviveHer breast attachment on EMT students' willingness and comfort in performing CPR on breasted and nonbreasted individuals.

Simul HealthcOct 1, 2026Read summary
Clinical ResearchFamily Medicine

Primary care practitioners' experiences managing urinary tract infections: a qualitative evidence synthesis.

This qualitative evidence synthesis explored the experiences of primary care practitioners (PCPs) managing urinary tract infections (UTIs) across various international settings.

Br J Gen PractOct 1, 2026Read summary
Case ReportGastroenterology

Gastric neuroendocrine tumours after prolonged proton pump inhibitor use.

A woman in her 40s with chronic gastro-oesophageal reflux disease had been on proton pump inhibitors for 20 years. She was diagnosed with gastric neuroendocrine tumours during an upper endoscopy.

BMJ Case RepOct 1, 2026Read case

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