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1999 articles

September 202624

Clinical ResearchGeriatrics

Behavior Change and Compliance Outcomes of a Novel Web-Based Health Behavior Tool Integrated Into Certified Exercise Practitioner Services: Twelve-Week, Two-Arm, Randomized Pre-Post Trial.

This randomized controlled trial evaluated the impact of a web-based health behavior tool, the FESS questionnaire, on health behaviors in 41 older adults (median age 65) receiving services from certified exercise…

J Med Internet ResSep 30, 2026Read summary
Clinical ResearchPulmonology

Open versus closed suctioning on lung volume and oxygenation in ARDS patients with PEEP 5-10 cmH2O: A randomized controlled trial.

This randomized controlled trial compared open suctioning (OS) and closed suctioning (CS) in 60 ARDS patients on mechanical ventilation with PEEP 5-10 cmH2O.

PLoS OneSep 30, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Association between personal birth companion and maternal mental health in low- and middle-income countries: a systematic review.

This systematic review examined the impact of personal birth companions on maternal mental health during labor and postpartum in low- and middle-income countries.

BMJ OpenSep 30, 2026Read summary
Clinical ResearchEmergency Medicine

Reducing Peripheral Intravenous Catheter Use in Adult Acute Care: A Systematic Review.

This systematic review evaluated interventions aimed at reducing peripheral intravenous catheter (PIVC) use in adult acute care settings.

Emerg Med AustralasSep 30, 2026Read summary
Case ReportGastroenterology

Intentional nail ingestion with caecal impaction: colonoscopic removal using a cap-assisted technique.

A woman with a history of recurrent nail ingestion presented with abdominal pain after swallowing multiple nails. Initial conservative management showed progressive migration of the nails, which clustered near the…

BMJ Case RepSep 30, 2026Read case
Case ReportGastroenterology

Lipomatous pseudohypertrophy of pancreas with chronic calcific pancreatitis presenting with nutritional dermatosis and type 3c diabetes.

A woman in her early 50s presented with erythema, scaling of the limbs, weight loss, anasarca, and chronic foul-smelling diarrhea, indicative of nutritional dermatosis due to malabsorption.

BMJ Case RepSep 30, 2026Read case
Clinical ResearchGastroenterology

Implementing a medical opinion leader-led management model to promote timely treatment initiation among screen-positive patients with upper gastrointestinal cancer in rural China: a cluster randomised controlled trial protocol.

This cluster randomised controlled trial aims to assess the effectiveness of a medical opinion leader-led management model in reducing treatment initiation time for screen-positive upper gastrointestinal cancer patients…

BMJ OpenSep 30, 2026Read summary
Clinical ResearchHematology

Clinical, economic, and quality-of-life outcomes of brexucabtagene autoleucel for the treatment of relapsed/refractory mantle cell lymphoma and B-cell acute lymphoblastic leukemia: A systematic literature review and meta-analysis.

This systematic literature review and meta-analysis evaluated the clinical, healthcare resource use, and quality-of-life outcomes of brexucabtagene autoleucel in adults with relapsed/refractory mantle cell lymphoma…

J Manag Care Spec PharmSep 30, 2026Read summary
Case ReportInfectious Diseases

Positive Syphilis Serology With Concurrent Disseminated Talaromycosis marneffei in a Patient With HIV: A Case Report.

A 37-year-old male with HIV presented with a rash and was initially diagnosed with secondary syphilis based on positive serology. After ampicillin treatment failed to improve his condition, he developed fever and cough.

Am J Case RepSep 30, 2026Read case
Case ReportOphthalmology

Autologous retinal transplant for macular hole in retinal detachment following bag-intraocular lens complex dislocation.

An elderly patient in their late 80s presented with total retinal detachment and a macular hole following pars plana vitrectomy for a dislocated capsular bag-intraocular lens complex.

BMJ Case RepSep 29, 2026Read case
Clinical ResearchCardiology

Incidence and Predictors of Complications After Transcatheter Aortic Valve Implantation According to VARC-3 Criteria: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled 57 studies involving 73 588 patients undergoing transcatheter aortic valve implantation (TAVI), with complications classified using VARC-3 criteria.

J Am Heart AssocSep 29, 2026Read summary
Case ReportEmergency Medicine

Rotational thromboelastometry guided transfusion in venom-induced consumptive coagulopathy following a haemotoxic snakebite.

A woman in her 30s presented with severe haemotoxic snake envenoming and venom-induced consumptive coagulopathy (VICC), leading to early multiorgan involvement.

BMJ Case RepSep 29, 2026Read case
Clinical ResearchOrthopedic Surgery

What to do with K-wires in displaced upper extremity fractures in children - where to bury or not.

This systematic review and meta-analysis evaluated the complication rates of buried versus exposed Kirschner wires (K-wires) in pediatric upper extremity fractures, involving 1,977 patients.

Eur J Trauma Emerg SurgSep 29, 2026Read summary
Clinical ResearchCardiology

The Effect of Carbetocin on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled QT/QTc Study in Healthy Adults.

This randomized controlled trial assessed the impact of a supratherapeutic dose of carbetocin on cardiac repolarization in 42 healthy adults.

Clin Transl SciSep 29, 2026Read summary
Clinical ResearchOncology (Medical)

Unveiling the Prognostic Power of Circulating Tumor DNA in Multiple Myeloma: A Systematic Review and Updated Meta-Analysis.

This systematic review and meta-analysis evaluated the prognostic significance of circulating tumor DNA (ctDNA) in 948 patients with multiple myeloma (MM).

Cancer MedSep 29, 2026Read summary
Clinical ResearchEndocrinology

Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.

TRIUMPH-2 was a double-blind, parallel-group, randomised, placebo-controlled phase 3 trial at 92 centres in eight countries. It assessed once-weekly retatrutide in adults with obesity and type 2 diabetes.

LancetSep 29, 2026Read summary
Case ReportOphthalmology

Bilateral Vortex Keratopathy in a Patient Receiving Long-Term Ribociclib Therapy.

A 67-year-old woman with metastatic breast cancer was found on routine eye examination to have bilateral whorl-like corneal epithelial deposits after four years of continuous ribociclib therapy.

Eye Contact LensSep 29, 2026Read case
Clinical ResearchNeurologyOpen access

Efficacy of transcranial alternating current stimulation on cognitive function in patients with dementia: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy of transcranial alternating current stimulation (tACS) on cognitive function in 357 dementia patients across 9 randomized controlled trials.

Neurol SciSep 29, 2026Read summary
Clinical ResearchPsychiatry

Designing Youth Early Intervention in Psychosis Services: A Secondary Framework Synthesis of Organisational Recommendations.

This systematic review synthesized organizational recommendations from 26 international guidelines on early intervention in psychosis (EIP) for youth.

Early Interv PsychiatrySep 29, 2026Read summary
Clinical ResearchEndocrinology

Petrelintide, a human amylin analogue for the treatment of obesity (ZUPREME 1): a randomised, double-blind, placebo-controlled, phase 2 trial.

This multicentre, randomised, double-blind, placebo-controlled phase 2 trial assessed once-weekly petrelintide in adults with obesity or overweight with hypertension or dyslipidaemia, without type 2 diabetes.

Lancet Diabetes EndocrinolSep 29, 2026Read summary
Case ReportMedical Genetics

A Heterozygous Variant in the GABBR2 Gene in a Girl With Clinical Classic Rett Syndrome.

A girl diagnosed with classic Rett syndrome exhibited developmental stagnation, loss of purposeful hand use, stereotypic movements, autonomic dysfunction, and behavioral issues.

Mol Genet Genomic MedSep 29, 2026Read case
Case ReportMedical Genetics

Longest surviving patient with a homozygous splice-altering EGFR pathogenic variant presenting with skin autoinflammation and a Bartter-like salt-losing tubulopathy.

An adolescent patient with a Bartter-like phenotype presented with progressive nephrocalcinosis, hypercalciuria, and skin autoinflammation.

J Med GenetSep 29, 2026Read case
Case ReportOphthalmology

Uveitis as a class effect of Bruton tyrosine kinase inhibitors: ibrutinib and zanubrutinib ocular toxicity.

A man in his early 50s with Waldenström macroglobulinaemia developed posterior uveitis while on ibrutinib, characterized by vitreous and retinal infiltrates.

BMJ Case RepSep 29, 2026Read case
Clinical ResearchGastroenterologyOpen access

Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness and safety of subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease.

Eur J PediatrSep 29, 2026Read summary

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