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1999 articles

September 202624

Case ReportNeurology

Biomarker-Guided Diagnosis of Riboflavin Transporter Deficiency Presenting as Seronegative Myasthenia Gravis: A Short Report from a Consanguineous Family.

A 3.5-year-old girl born to consanguineous parents developed bilateral ptosis, followed by dysphagia, dysphonia, facial diplegia, stridor, and respiratory compromise.

Genet Test Mol BiomarkersSep 26, 2026Read case
Case ReportGeneral SurgeryOpen access

Delayed Metal Hypersensitivity from Surgical Clips Causing Progressive Neuropathy.

A 65-year-old male presented with progressive abdominal pain, bilateral lower extremity neuropathy, postprandial nausea, and autonomic dysfunction after laparoscopic cholecystectomy and inguinal hernia repair.

CRSLSSep 26, 2026Read case
Case ReportAnesthesiologyOpen access

Analgesic Efficacy and Motor-Sparing Properties of Superior Trunk Block versus Interscalene Brachial Plexus Block with Liposomal Bupivacaine for Shoulder Arthroscopy: A Randomized Controlled Trial.

The interscalene brachial plexus block (ISB) is widely regarded as the most commonly used regional anesthesia technique for perioperative analgesia in arthroscopic shoulder surgery; however, it is associated with a high…

Drug Des Devel TherSep 26, 2026Read case
Case ReportOtolaryngology (ENT)Open access

Recurrent Juvenile Nasopharyngeal Angiofibroma: Two Cases Emphasizing the Role of Follow-Up and Staging in Surgical Planning.

Two cases of recurrent juvenile nasopharyngeal angiofibroma (JNA) in adolescent males are presented. The first case involved a 21-year-old with a history of incomplete resection and poor follow-up, presenting with…

Int Med Case Rep JSep 26, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Liposomal Bupivacaine versus Bupivacaine Hydrochloride Plus Dexamethasone for Combined Adductor Canal and iPACK Blocks in Total Knee Arthroplasty: A Randomized Controlled Trial.

This randomized controlled trial compared postoperative analgesia and quadriceps recovery between liposomal bupivacaine and bupivacaine hydrochloride plus dexamethasone in 60 patients undergoing total knee arthroplasty.

Drug Des Devel TherSep 26, 2026Read summary
Clinical ResearchGastroenterology

Quantifying Pancreatic Fat Using a Free-Breathing Acquisition in Adults With Obesity Undergoing Diet-Induced Weight Loss-Results From the LION Study.

This randomized controlled trial evaluated a free-breathing six-echo radial stack-of-stars acquisition for quantifying pancreatic fat in 18 adults with obesity undergoing diet-induced weight loss.

NMR BiomedSep 26, 2026Read summary
Clinical ResearchPulmonology

Early cardiovascular vulnerability after acute exacerbation of COPD: a time-windowed systematic review and evidence map.

This systematic review and evidence map examined cardiovascular events during and after exacerbations of COPD, asthma, or bronchiectasis, with COPD as the primary evidence base.

Respir MedSep 26, 2026Read summary
Clinical ResearchPulmonologyOpen access

Clinical Characteristics and Factors Associated with One-Year Smoking Cessation Among Smokers with COPD: A Subgroup Analysis of a Multicentre Randomised Trial.

This multicentre randomised trial evaluated factors associated with one-year smoking cessation among smokers with COPD. Of 172 patients analyzed, 32 (18.6%) achieved cessation, with 25.8% in the immediate referral group…

Int J Chron Obstruct Pulmon DisSep 26, 2026Read summary
Clinical ResearchEndocrinology

Empagliflozin Promotes Natriuresis in Diabetic Patients with Cirrhotic Refractory Ascites: A Proof-of-Concept Study.

This randomized controlled trial investigated the effects of empagliflozin on natriuresis in 21 diabetic patients with decompensated cirrhosis and refractory ascites.

J Gastrointestin Liver DisSep 26, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Effectiveness of Lactobacillus-supplemented eradication therapy for Helicobacter pylori: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the effectiveness of Lactobacillus-supplemented Helicobacter pylori eradication therapy across 32 randomized controlled trials involving 4,010 patients.

Eur J Clin PharmacolSep 26, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Somatic PIK3CA and PTEN mutations with endothelial PI3K/AKT/mTOR activation in RAS-negative brain arteriovenous malformations.

This report details two autopsy-confirmed brain arteriovenous malformations (bAVMs) with somatic PIK3CA mutations, one of which also had a PTEN alteration.

J Neuropathol Exp NeurolSep 26, 2026Read case
Clinical ResearchObstetrics & Gynecology

Rethinking Prevention of Recurrent Bacterial Vaginosis: A Comparative Effectiveness Network Meta-Analysis.

This network meta-analysis evaluated the effectiveness of various preventive strategies for recurrent bacterial vaginosis (BV) in nonpregnant women.

J Low Genit Tract DisSep 26, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Diagnostic Strategies After Negative Colposcopy in High-Grade Cervical Cytology: A Multicenter Randomized Trial.

This multicenter randomized trial evaluated diagnostic strategies for detecting HSIL+ in women with high-grade cervical cytology and negative colposcopy.

J Low Genit Tract DisSep 26, 2026Read summary
Case ReportGastroenterology

Vulvar Crohn's-Case Series and Review of Treatment With Ustekinumab.

This case series presents three patients with cutaneous vulvar Crohn's disease (VCD), a rare and challenging condition. Each patient was treated with different biologic agents.

J Low Genit Tract DisSep 26, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Comparative pain relief and functional outcomes following robotic-assisted versus conventional total knee arthroplasty: a GRADE-assessed meta-analysis with meta-regression of randomized controlled trials.

This meta-analysis of 24 randomized controlled trials involving 3,425 patients compared robotic-assisted total knee arthroplasty (RA-TKA) with conventional TKA (C-TKA).

J Robot SurgSep 25, 2026Read summary
Clinical ResearchCardiology

Comparison of bivalirudin versus heparin in percutaneous coronary intervention for patients with acute coronary syndrome: A meta-analysis.

This meta-analysis compared bivalirudin and heparin in patients with acute coronary syndrome undergoing percutaneous coronary intervention, including 11 RCTs and 17 cohort studies with 584,249 patients.

Medicine (Baltimore)Sep 25, 2026Read summary
Clinical ResearchHematologyOpen access

ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review.

This systematic review evaluated the impact of ATM mutations in myelodysplastic neoplasms (MDS), acute myeloid leukemia (AML), and myeloproliferative neoplasms (MPN).

Med OncolSep 25, 2026Read summary
Clinical ResearchUrologyOpen access

Unravelling deregulated metabolites in seminal plasma of infertile men: a systematic review and bioinformatic analysis.

This systematic review analyzed metabolomic studies comparing seminal plasma metabolites in healthy and infertile men. It included 20 studies and identified 284 metabolites, with specific alterations linked to…

J Mol Med (Berl)Sep 25, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Comparative efficacy of brain-computer interface-coupled robotic rehabilitation, robot-assisted therapy, and motor imagery for upper-limb motor recovery after stroke: a systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the efficacy of brain-computer interface-coupled robotic rehabilitation (BCI-robot), robot-assisted therapy, motor imagery, and conventional rehabilitation for…

Neurol SciSep 25, 2026Read summary
Clinical ResearchNeurology

Wearable Sensors in Gait Assessment for Parkinson Disease and Stroke in Real-World Environments: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the use of wearable sensors for gait assessment in patients with Parkinson disease (PD) and stroke. It included 43 studies, primarily focusing on PD (2774 participants).

J Med Internet ResSep 25, 2026Read summary
Case ReportInfectious Diseases

Lymphocutaneous sporotrichosis: A case report from southeastern China and review of the literature.

A 53-year-old male presented with multiple ulcerated lesions, leading to a diagnosis of lymphocutaneous sporotrichosis. Pathological analysis showed an inflammatory reaction, while imaging studies were normal.

Medicine (Baltimore)Sep 25, 2026Read case
Clinical ResearchPulmonology

Predictors of Pulmonary Complications After Rib Fractures: Systematic Review and Meta-Analyses.

This systematic review and meta-analysis examined multivariable-adjusted predictors of pulmonary complications in adults with blunt rib fractures.

J Surg ResSep 25, 2026Read summary
Clinical ResearchOncology (Medical)

Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.

ROAM/EORTC-1308 was an international, multicentre, open-label, phase 3 randomised trial comparing adjuvant radiotherapy with observation after complete resection of newly diagnosed WHO grade 2 atypical meningioma.

LancetSep 25, 2026Read summary
Case ReportInfectious DiseasesOpen access

Aggressive brainstem listeria abscess in an immunocompetent individual: A case report.

An immunocompetent patient in their late 50s presented with neurolisteriosis characterized by multifocal brainstem abscesses. The case involved an extensive negative infectious workup and a complex antibiotic regimen.

Neurol SciSep 25, 2026Read case

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