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2000 articles
October 202624
5-year survival rate and determinants of decreased survival among patients with breast cancer in Africa: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the 5-year survival rate of breast cancer patients in Africa, analyzing 55 studies with 19,577 participants. The pooled 5-year survival rate was found to be 40.38%.
Immersive 3D vs Physical Simulation in Training Novices for Laser-Based Endourological Procedures: Protocol for a Randomized Controlled Trial.
This randomized controlled trial aims to compare immersive 3D simulation and physical simulation training for novice medical students in endourological laser-based procedures.
Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.
This individual participant data meta-analysis examined amyloid PET scans from 49,227 participants across 53 studies to establish Centiloid positivity cutoffs for Alzheimer disease diagnosis.
Reliability of Childhood Autism Rating Scale, Second Edition, Assessments Using Telepsychiatry for Children With Neurodevelopmental Disorders and Their Caregivers: Randomized Feasibility Study.
This randomized feasibility study evaluated the interrater reliability of the Childhood Autism Rating Scale, Second Edition (CARS2) between telepsychiatry and face-to-face assessments in 73 children aged 6 to 17 with…
Presumed transdermal superwarfarin toxicity in a pest control worker.
A man in his early 60s presented with dyspnoea and a 2-3 month history of spontaneous mucocutaneous bleeding. Laboratory tests showed unmeasurably elevated INR and activated partial thromboplastin time.
Haemophagocytic lymphohistiocytosis triggered by Kikuchi-Fujimoto disease: a diagnostic challenge.
A man in his 40s presented with fever, confusion, a widespread erythematous rash, weight loss, and generalized lymphadenopathy over three weeks.
Chronic posthypoxic myoclonus: Lance-Adams syndrome.
A man in his 20s developed chronic intentional myoclonus following two cardiac arrests, leading to persistent generalized myoclonic seizures.
Same-day diagnosis and robotic resection of rare primary pulmonary melanoma: a robotic bronchoscopy-guided approach.
A man in his 70s presented with a lingular pulmonary nodule suspicious for non-small cell lung cancer. He underwent robotic navigation bronchoscopy for biopsy, which was followed by robotic-assisted thoracic surgery.
Australian Digital Mental Health Services for Anxiety and Depression: Meta-Analysis and Comparison Study.
This meta-analysis evaluated the effectiveness and uptake of three Australian digital mental health services (DMHSs) for anxiety and depression. Over 282,000 consumers accessed these services from 2013 to 2021.
Eosinophilic angiocentric fibrosis in paediatric IgG4-related disease.
A young girl presented with a 1.5-year history of progressive bilateral upper eyelid swelling and proptosis, more pronounced on the right.
Approach to management of walled-off necrosis secondary to trauma-induced pancreatitis in a limited-resource setting.
A patient with trauma-induced pancreatitis developed a walled-off necrosis (WON) characterized by a necrotic peripancreatic collection. Imaging revealed a mature collection with necrotic debris.
Immune-related colitis following head and neck reconstructive surgery in a patient receiving long-term nivolumab.
A man with gastric cancer, receiving long-term nivolumab and prednisolone for immune-related myositis, underwent subtotal glossectomy for advanced tongue cancer. On postoperative day 4, he developed grade 3 diarrhoea.
Randomised controlled trial of fluoxetine versus naltrexone in compulsive sexual behaviour disorder.
This randomized controlled trial compared the efficacy and tolerability of fluoxetine and naltrexone in 80 participants with compulsive sexual behaviour disorder (CSBD).
Surgical and orthodontic management of class III malocclusion in monozygotic twins using bilateral sagittal split osteotomy.
This case report details the surgical and orthodontic management of class III malocclusion in identical twin sisters in their early 20s, both presenting with mandibular prognathism.
Hepatitis A-associated oxidative haemolysis in a patient with glucose-6-phosphate dehydrogenase deficiency with co-inherited sickle cell trait.
A young male presented with pruritus, nausea, and jaundice following travel to West Africa, lacking hepatitis A vaccination.
Adamantinoma-like Ewing sarcoma of the bladder.
A patient presented with a bladder tumor initially diagnosed as urothelial carcinoma following transurethral resection. After receiving neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and…
Duplicated spermatic cord encountered during inguinal hernia repair.
A male patient in his seventies presented for elective open right inguinal hernia repair. During the procedure, complete duplication of the spermatic cord was identified, with two distinct structures each containing a…
Efficacy and safety of MEK inhibitors for NF1-associated symptomatic, inoperable plexiform neurofibromas: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of MEK inhibitors for treating symptomatic, inoperable plexiform neurofibromas in patients with neurofibromatosis type 1 (NF1).
Hernia, mesh, microbes, and phage promise: Mapping 35 years of evidence through a systematic review.
This systematic review examined published evidence on microbiology and outcomes of hernia mesh infections, including studies from 1990–2025. Of 584 studies meeting inclusion criteria, 32 contributed to meta-analysis.
#aware.hiv Europe study: protocol for a stepped-wedge cluster randomised trial of a multimodal hospital-based implementation strategy targeting HIV indicator-condition-guided testing in European hospitals.
The #aware.hiv Europe study is a stepped-wedge cluster randomised trial conducted in 30 hospitals across ten European countries, aiming to improve HIV testing rates among patients with HIV indicator conditions.
Impact of opioid-free general anesthesia with locoregional blocks during breast cancer surgery on systemic inflammatory response: results from a randomized controlled trial.
This randomized controlled trial evaluated the effects of opioid-free general anesthesia with locoregional blocks (OfGA) versus traditional opioid-based general anesthesia (GA) on postoperative inflammation in breast…
Objective, long-term mobility data in patients with chronic pain after lumbar spine surgery treated with spinal cord stimulation-a prospective, multicenter trial.
This multicenter clinical trial evaluated the long-term effects of spinal cord stimulation (SCS) on mobility in 50 patients with chronic pain following lumbar spine surgery.
Clinical utility of randomized controlled trials of regional anesthesia for lower-extremity surgery: a systematic review.
This systematic review evaluated the clinical utility and transparency of randomized controlled trials (RCTs) on regional anesthesia (RA) for lower-extremity surgeries.
A phase III randomized study: Immunogenicity and safety of a quadrivalent meningococcal conjugate vaccine in healthy adults, adolescents, and children in India and healthy adolescents and children in South Africa.
This Phase III randomized controlled trial assessed the immunogenicity and safety of a single dose of MenACYW-TT in healthy adults, adolescents, and children in India and in adolescents and children in South Africa.
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