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2000 articles
September 202624
Carfilzomib plus induction chemotherapy for children with relapsed or refractory acute lymphoblastic leukemia.
This phase II clinical trial evaluated the efficacy of carfilzomib combined with induction chemotherapy (CFZ-VXLD) in pediatric patients aged 1 month to <21 years with relapsed or refractory acute lymphoblastic leukemia…
Beyond β-amyloid: transthyretin cerebral amyloid angiopathy.
A 44-year-old man presented with recurrent upper-limb and perioral sensory symptoms, later identified as transient focal neurological episodes.
Resolution of Phlegmasia Cerulea Dolens in a Patient with Metastatic Cancer and an Inferior Vena Cava Filter.
A 69-year-old man with metastatic non-small cell lung cancer developed rapidly progressive phlegmasia cerulea dolens despite recent negative imaging and an inferior vena cava filter.
Acquired paroxysmal dysarthria-ataxia syndrome: A systematic review of clinical and MRI findings.
This systematic review examined acquired paroxysmal dysarthria-ataxia syndrome (PDAS) in 31 patients across 25 studies, revealing that PDAS is not limited to Multiple Sclerosis.
Single-Area Versus Multiple-Area Passive Recharge Burst During Spinal Cord Stimulator Trials: An Independent Prospective Randomized, Double-Blind Study.
This randomized controlled trial evaluated the effectiveness of single-area versus multi-area passive recharge burst therapy in a neurostimulation naive population for chronic pain management.
Rethinking Prevention of Recurrent Bacterial Vaginosis: A Comparative Effectiveness Network Meta-Analysis.
This network meta-analysis evaluated the effectiveness of various preventive strategies for recurrent bacterial vaginosis (BV) in nonpregnant women.
Bacterial orbital infection leading to orbital exenteration: a case series.
This case series describes three people who underwent orbital exenteration for bacterial infection. Two infections arose from odontogenic sources; the third was periorbital/orbital necrotizing fasciitis associated with…
Electrical Impedance Tomography-Guided Precision Nursing in an Older Patient With Septic Shock and ARDS: A Case Report.
A 79-year-old patient with septic shock, ARDS, and MODS underwent precision nursing management utilizing electrical impedance tomography (EIT).
Perineural invasion and Schwann cell-like phenotypic changes in head and neck adenoid cystic carcinoma: A systematic review and meta-analysis.
This systematic review and meta-analysis examined perineural invasion (PNI) and Schwann cell-like phenotypic changes in head and neck adenoid cystic carcinoma (ACC).
Biomarker-Guided Diagnosis of Riboflavin Transporter Deficiency Presenting as Seronegative Myasthenia Gravis: A Short Report from a Consanguineous Family.
A 3.5-year-old girl born to consanguineous parents developed bilateral ptosis, followed by dysphagia, dysphonia, facial diplegia, stridor, and respiratory compromise.
Quantifying Pancreatic Fat Using a Free-Breathing Acquisition in Adults With Obesity Undergoing Diet-Induced Weight Loss-Results From the LION Study.
This randomized controlled trial evaluated a free-breathing six-echo radial stack-of-stars acquisition for quantifying pancreatic fat in 18 adults with obesity undergoing diet-induced weight loss.
Delayed Metal Hypersensitivity from Surgical Clips Causing Progressive Neuropathy.
A 65-year-old male presented with progressive abdominal pain, bilateral lower extremity neuropathy, postprandial nausea, and autonomic dysfunction after laparoscopic cholecystectomy and inguinal hernia repair.
A machine learning-based ecological momentary intervention for mental health promotion in youth: a micro-randomized trial.
This micro-randomized trial investigated the effects of machine learning (ML)-based ecological momentary interventions (EMIs) on mental health outcomes in 49 youth participants.
Therapeutic drug monitoring-guided management of venlafaxine overdose in an adolescent: a case report.
An adolescent presented with severe venlafaxine overdose, exhibiting tachycardia, mydriasis, and generalized tonic-clonic seizures. Initial plasma levels were 7800 ng/mL, significantly above therapeutic limits.
Analgesic Efficacy and Motor-Sparing Properties of Superior Trunk Block versus Interscalene Brachial Plexus Block with Liposomal Bupivacaine for Shoulder Arthroscopy: A Randomized Controlled Trial.
The interscalene brachial plexus block (ISB) is widely regarded as the most commonly used regional anesthesia technique for perioperative analgesia in arthroscopic shoulder surgery; however, it is associated with a high…
Clinical Characteristics and Factors Associated with One-Year Smoking Cessation Among Smokers with COPD: A Subgroup Analysis of a Multicentre Randomised Trial.
This multicentre randomised trial evaluated factors associated with one-year smoking cessation among smokers with COPD. Of 172 patients analyzed, 32 (18.6%) achieved cessation, with 25.8% in the immediate referral group…
Recurrent Juvenile Nasopharyngeal Angiofibroma: Two Cases Emphasizing the Role of Follow-Up and Staging in Surgical Planning.
Two cases of recurrent juvenile nasopharyngeal angiofibroma (JNA) in adolescent males are presented. The first case involved a 21-year-old with a history of incomplete resection and poor follow-up, presenting with…
Liposomal Bupivacaine versus Bupivacaine Hydrochloride Plus Dexamethasone for Combined Adductor Canal and iPACK Blocks in Total Knee Arthroplasty: A Randomized Controlled Trial.
This randomized controlled trial compared postoperative analgesia and quadriceps recovery between liposomal bupivacaine and bupivacaine hydrochloride plus dexamethasone in 60 patients undergoing total knee arthroplasty.
Empagliflozin Promotes Natriuresis in Diabetic Patients with Cirrhotic Refractory Ascites: A Proof-of-Concept Study.
This randomized controlled trial investigated the effects of empagliflozin on natriuresis in 21 diabetic patients with decompensated cirrhosis and refractory ascites.
Early cardiovascular vulnerability after acute exacerbation of COPD: a time-windowed systematic review and evidence map.
This systematic review and evidence map examined cardiovascular events during and after exacerbations of COPD, asthma, or bronchiectasis, with COPD as the primary evidence base.
Effectiveness of Lactobacillus-supplemented eradication therapy for Helicobacter pylori: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the effectiveness of Lactobacillus-supplemented Helicobacter pylori eradication therapy across 32 randomized controlled trials involving 4,010 patients.
Somatic PIK3CA and PTEN mutations with endothelial PI3K/AKT/mTOR activation in RAS-negative brain arteriovenous malformations.
This report details two autopsy-confirmed brain arteriovenous malformations (bAVMs) with somatic PIK3CA mutations, one of which also had a PTEN alteration.
Diagnostic Strategies After Negative Colposcopy in High-Grade Cervical Cytology: A Multicenter Randomized Trial.
This multicenter randomized trial evaluated diagnostic strategies for detecting HSIL+ in women with high-grade cervical cytology and negative colposcopy.
Vulvar Crohn's-Case Series and Review of Treatment With Ustekinumab.
This case series presents three patients with cutaneous vulvar Crohn's disease (VCD), a rare and challenging condition. Each patient was treated with different biologic agents.
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