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1999 articles
October 202624
ULTRAWIDE-FIELD COLOR FUNDUS IMAGES AND ARTIFICIAL INTELLIGENCE FOR DIAGNOSIS OF DIABETIC RETINOPATHY: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed artificial intelligence (AI) for diabetic retinopathy (DR) evaluation using ultrawide-field fundus images.
Acetic acid chromoendoscopy for detection of neoplastic Barrett's oesophagus: stepped wedge cluster randomised controlled trial (ACID-trial).
This prospective, open-label, stepped-wedge cluster randomised trial assessed whether acetic acid chromoendoscopy (AAC) improved detection of dysplasia or oesophageal adenocarcinoma during Barrett’s oesophagus…
Natural History and Therapeutic Response in Ophthalmic Plasminogen Deficiency: Two Cases and Call for Registry-Based Data.
The report describes two patients with type 1 plasminogen deficiency and ligneous conjunctivitis. A 65-year-old woman with untreated disease had recurrent conjunctivitis, ultimately requiring enucleation, and developed…
Effectiveness of cardiac resynchronization therapy in cancer therapy-related cardiac dysfunction: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed cardiac resynchronization therapy (CRT) outcomes in patients with cancer therapy-related cardiac dysfunction (CTRCD).
Feasibility and safety of an exercise-based prehabilitation intervention before cancer surgery: a pilot randomised controlled trial.
This single-centre pilot randomised controlled trial assessed the feasibility and safety of supervised aerobic prehabilitation before surgery in patients with breast, colorectal, or prostate cancer.
Calorie-Restricted DASH, Carbohydrate-Restricted, and Low-Purine Diets for Weight Loss and Urate Control in Men With Overweight or Obesity and Hyperuricemia: A Randomized Trial.
This 12-week, open-label, active-comparator randomized trial compared calorie-restricted carbohydrate-restricted, DASH, and low-purine balanced diets in 102 men with overweight or obesity and hyperuricemia.
Ultra high-density, 4096-channel intraoperative neurophysiological brain mapping for functional localization of the human central sulcus.
During resection of a right parafalcine meningioma in a 56-year-old man, four flexible 1024-electrode micro-ECoG arrays were used to record somatosensory evoked potentials from the peri-Rolandic cortex during…
Excess Liver Fat in Type 2 Diabetes Stratified by Intrapancreatic Fat Deposition: A Meta-Analysis of Dual-Organ MRI Studies.
This meta-analysis pooled dual-organ MRI studies comparing liver fat content (LFC) in people with type 2 diabetes (T2DM) and non-diabetic controls, and examined whether study-level intrapancreatic fat deposition (IPFD)…
Bronchial Thermoplasty in Severe Asthma: Bridging Randomised and Real-World Evidence: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed bronchial thermoplasty (BT) efficacy and safety in adults with severe uncontrolled asthma, analysing randomised controlled trials (RCTs) separately from observational…
Spiked Helmet Sign in the Early Post-Heart Transplantation Period: A Dramatic STEMI Mimic in a Structurally Normal Donor Heart.
A 36-year-old woman with severe dilated cardiomyopathy underwent heart transplantation and subsequently developed subarachnoid hemorrhage and septic shock.
From Alert to Action: Electronic Practice Advisory Improves DSMES Referrals Over 18 Months.
This cluster-randomized controlled trial in primary care practices in central North Carolina tested whether an electronic health record best practice advisory (BPA) increased referrals to diabetes self-management…
Evaluating a multi-vaccine respiratory immunization strategy involving SARS-CoV-2, pneumococcal, and influenza vaccines in adults: A randomized, open-label, multicenter, controlled, non-inferiority Phase IV trial in China.
This randomized, open-label, multicenter Phase IV trial in China assessed immunogenicity and safety when adults aged ≥18 years received an inactivated SARS-CoV-2 vaccine with PPV23 and IIV4, compared with separate…
Ruxolitinib for the treatment of pediatric acute and chronic steroid-refractory graft-versus-host disease: Efficacy, safety, and outcomes.
This single-center retrospective study assessed ruxolitinib in children under 18 years with steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
EVALUATING THE EFFICACY AND SAFETY OF TOPICAL DIFLUPREDNATE IN PATIENTS WITH CHRONIC CENTRAL SEROUS CHORIORETINOPATHY.
This pilot, open-label randomized controlled trial compared topical difluprednate, oral eplerenone, and observation in adults with chronic or relapsing central serous chorioretinopathy.
Effects of Aerobic Exercise on Autonomic and Endothelial Function and Splanchnic Hemodynamics in Compensated Cirrhosis: RCT Study.
This parallel-group randomised controlled trial assessed 16 weeks of moderate-intensity aerobic exercise plus nutritional consultation versus nutritional consultation alone in 50 sedentary patients with compensated…
Semaglutide modulates explore/exploit decision-making in major depressive disorder: A randomized clinical trial.
This secondary analysis of a randomized clinical trial examined whether semaglutide affected explore/exploit decision-making in 72 participants with major depressive disorder (MDD).
Prophylactic Low-Dose Esketamine for Prevention of Intraoperative Penile Erection During Ureteroscopic Surgery Under General Anesthesia: A Randomized, Double-Blind, Placebo-Controlled Trial.
Intraoperative penile erection (IPE) during ureteroscopic surgery may interrupt surgical procedures and increase the risk of urethral injury.
METASTATIC UROTHELIAL CARCINOMA OF THE BLADDER TO THE RETINA: A CLINICOPATHOLOGIC CORRELATION AND REVIEW OF THE LITERATURE.
A patient with urothelial carcinoma of the bladder had a large yellow-white lesion in the superotemporal retina of the left eye.
Outcomes of Mindful Mood Balance for Moms, online mindfulness-based cognitive therapy for perinatal depressive relapse prevention in the USA: a two-arm, single-blind, pragmatic randomised clinical trial.
This single-blind, pragmatic randomised clinical trial tested a web-based mindfulness-based cognitive therapy programme plus usual care against usual care alone in euthymic pregnant women with recurrent depression and…
A multifaceted intervention to increase bystander CPR rates after out-of-hospital cardiac arrest in France: a stepped-wedge, cluster-randomised, controlled trial.
This stepped-wedge, cluster-randomised controlled trial assessed a coordinated intervention to increase bystander CPR before EMS arrival among adults with non-traumatic out-of-hospital cardiac arrest in France.
Addressing unilateral lambdoid craniosynostosis using endoscopic suturectomy and barrel-stave osteotomies: surgical technique and literature review.
A healthy 2-month-old boy presented with features of left unilateral lambdoid craniosynostosis, including occipitoparietal flattening, ipsilateral mastoid bulge, contralateral parietal bulge, and ear-level asymmetry; 3D…
Systematic review and meta-analysis of mesh versus suture repairs of small umbilical hernias (≤ 2 cm).
This systematic review and meta-analysis compared mesh with suture repair for small umbilical hernias (defects ≤ 2 cm). The primary outcome was postoperative recurrence; secondary outcomes included complications and…
Association between rheumatic diseases and glaucoma risk: a systematic review and meta-analysis of 5.7 million individuals.
This systematic review and meta-analysis examined glaucoma occurrence and risk among people with rheumatic diseases (RD), drawing on 18 studies with 5,766,143 participants.
EFFICACY AND SAFETY OF SUBTHRESHOLD LASER IN PATIENTS WITH ACUTE CENTRAL SEROUS CHORIORETINOPATHY: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of subthreshold laser for acute central serous chorioretinopathy (CSC), including six randomized controlled trials with 401 participants.
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