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2000 articles
October 202624
Nutraceuticals and phytoceuticals in the treatment of bipolar disorder: A systematic review and network meta-analysis.
This systematic review and network meta-analysis assessed randomized controlled trials of nutraceuticals and phytoceuticals for bipolar disorder. Twenty-eight trials involving 2,222 participants evaluated 22 treatments.
Mechanical Thrombectomy Versus Anticoagulation Alone in Intermediate-High Risk PE: Improved Functional 90-Day Outcomes in STORM-PE RCT.
STORM-PE was a multicentre randomised trial comparing computer-assisted vacuum thrombectomy (CAVT) plus anticoagulation with anticoagulation alone in 100 patients with acute intermediate-high-risk pulmonary embolism.
The utility of magnetic resonance imaging of the spinal cord in paediatric transverse myelitis: A systematic review.
This systematic review assessed spinal cord MRI findings, agreement with CSF inflammation, and prognostic associations in children with monophasic acute transverse myelitis.
Microperimetry Sensitivity Changes at the Functional Transition Zone and at the EZ Margins in X-Linked Retinitis Pigmentosa Treated With Gene Therapy.
This post-hoc analysis of the randomized Skyline trial examined how photoreceptor ellipsoid-zone (EZ) structure related to microperimetry sensitivity in eyes with X-linked retinitis pigmentosa treated with gene therapy.
SYSTEMATIC REVIEW AND BRAZILIAN EXPERT CONSENSUS ON THE USE OF BIOSIMILARS IN INFLAMMATORY BOWEL DISEASE: BRAZILIAN ORGANIZATION FOR CROHN'S AND COLITIS.
This systematic review and Brazilian expert consensus assessed biosimilar use in inflammatory bowel disease (IBD), addressing clinical, therapeutic, and economic questions.
Repeated remimazolam sedation for interstitial brachytherapy in cervical cancer: a randomized controlled trial.
This randomized controlled trial evaluated the safety and efficacy of repeated remimazolam sedation compared to propofol in 100 patients with cervical cancer undergoing interstitial brachytherapy.
N-acetylcysteine mouthwash for prevention of oral mucositis in hematopoietic cell transplant recipients: a double-blind randomized controlled trial.
This double-blind randomized controlled trial evaluated the efficacy of N-acetylcysteine (NAC) mouthwash in preventing oral mucositis (OM) in 106 hematopoietic cell transplant (HCT) recipients.
Image-Guided Cervicotomy and Recurrent Laryngeal Nerve Reinnervation in Zone II Glass Neck Trauma: A Case Report.
A 45-year-old woman with penetrating neck trauma from glass fragments presented hemodynamically stable, without airway compromise. Imaging revealed multiple retained glass foreign bodies but no major vascular injuries.
Interference of iron deficiency in glycated hemoglobin testing and its clinical implications: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of iron deficiency anemia (IDA) and latent iron deficiency (LID) on glycated hemoglobin (HbA1c) concentrations.
Stepwise dual antiplatelet therapy de-escalation versus standard therapy for 12 months in patients with bifurcation lesions undergoing drug-coated balloon angioplasty: Insights from the REC-CAGEFREE II trial.
This prespecified subgroup analysis of the multicentre randomised REC-CAGEFREE II trial compared stepwise dual antiplatelet therapy (DAPT) de-escalation with 12-month standard DAPT in patients with acute coronary…
Improvement of image quality and diagnostic accuracy of novel ferumoxytol-enhanced magnetic resonance coronary angiography: compared to non-contrast enhanced imaging.
This retrospective analysis of a prospective clinical trial compared ferumoxytol-enhanced with non-contrast coronary magnetic resonance angiography (CMRA) in 29 patients, using invasive coronary angiography as the…
Metabolomic biomarkers and metabolic remodelling in genetically characterised hypertrophic cardiomyopathy: a systematic review.
This systematic review examined metabolomic evidence in 1511 participants with genetically characterised hypertrophic cardiomyopathy (HCM).
Predictors and causes of 30-day failure after shunt placement in pediatric hydrocephalus: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated 30-day failure rates of ventriculoperitoneal (VP) shunts in pediatric hydrocephalus, analyzing data from 11,596 patients.
Should I drink water or wine? Impacts of online nutritional counseling on the alcohol consumption of elderly individuals with mild cognitive impairment : Secondary Data Analysis from the RCT "BrainFit-Nutrition".
This secondary data analysis from a randomized controlled trial evaluated the effects of nutritional counseling on alcohol consumption in 189 elderly individuals with mild cognitive impairment (MCI) over 12 months.
Trial-specific absolute disease-free survival effects of postoperative PD-1/PD-L1 blockade after complete resection of NSCLC: A systematic review.
This systematic review estimated absolute disease-free survival (DFS) effects of postoperative single-agent PD-1/PD-L1 blockade after complete resection of non-small-cell lung cancer.
Effects of exercise and educational programs on long-term quality of life, anxiety, and depression in breast cancer survivors: an exploratory secondary analysis of the Setouchi breast project-10 randomized controlled trial.
This exploratory secondary analysis of a randomized controlled trial examined exercise and education for 342 patients with stage 0–III breast cancer within one year of completing treatment.
Boesenbergia rotunda extract-based mucoadhesive mouth gargle for chemoradiation-induced oral mucositis: A prospective randomized controlled study.
This randomized controlled trial evaluated the efficacy of a Boesenbergia rotunda extract-based mouth gargle in managing chemoradiation-induced oral mucositis in head and neck cancer patients.
Exertional Rhabdomyolysis With Moderate Creatine Kinase Elevation and Marked Transaminase Elevation but Preserved Synthetic Function: A Case Report.
A 43-year-old man presented with fatigue, nausea, and myalgia following a 3000-m run. Laboratory tests revealed moderate creatine kinase (CK) elevation at 2828 U/L alongside significantly elevated transaminases: AST at…
Continuous infusion of granulocyte colony-stimulating factor is associated with an advantage in neutrophil recovery in pediatric oncologic disorders.
This randomized controlled trial evaluated the effects of continuous infusion versus injection of granulocyte colony-stimulating factor (G-CSF) on neutrophil recovery in 20 pediatric oncology patients.
Prevalence of osteoporosis and low bone mass in men with prostate cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prevalence of osteoporosis and low bone mass in 91,913 men with prostate cancer (PCa).
Robot-assisted versus non-robotic partial nephrectomy for completely endophytic renal tumors: a systematic review and meta-analysis.
This systematic review and meta-analysis compared robot-assisted partial nephrectomy (RAPN) with laparoscopic (LPN) and open partial nephrectomy (OPN) for completely endophytic renal tumors (CERTs) in 896 patients.
Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Cognitive Outcome after Stroke: A Systematic Review.
This systematic review examined the association between the BDNF Val66Met polymorphism and cognitive outcomes in 2,494 adults post-stroke.
Learning curves in robotic and laparoscopic colorectal surgery: a systematic review.
This systematic review evaluated learning curves in laparoscopic and robotic colorectal surgery, analyzing 114 studies with 167 learning-curve analyses.
Complete Regression of 11 Hepatic Metastases in Metastatic Pancreatic Adenosquamous Carcinoma and the Role of GPT in Patient Navigation.
A 65-year-old man with resected pancreatic adenosquamous carcinoma (pT3 pN2, R0) had 11 liver lesions interpreted as metastases on MRI.
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