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2000 articles
October 202624
Effects of SGLT-2 Inhibitors on Plasma Concentrations and Renal Clearance of the Risk Marker Trimethylamine-N-Oxide in Patients With Type-2 Diabetes.
This randomized controlled trial investigated the effects of SGLT-2 inhibitors empagliflozin and dapagliflozin on plasma levels and renal clearance of trimethylamine-N-oxide (TMAO) in patients with Type 2 diabetes.
Facilitators of Peer Support Among Patients With Chronic Kidney Disease: A Systematic Review and Qualitative Meta-Synthesis.
This systematic review and qualitative meta-synthesis examined facilitators of peer support among patients with chronic kidney disease (CKD).
Efficacy and Safety of Oral Non-Statin Lipid-Lowering Therapies in Dyslipidaemia: A Systematic Review and Network Meta-Analysis.
This systematic review and network meta-analysis evaluated the efficacy and safety of oral non-statin lipid-lowering therapies in adults with dyslipidaemia.
Nonarmored GCC-Targeting CAR T-cell Therapy Demonstrates Significant Efficacy in Patients with Advanced Colorectal Cancer.
This phase I clinical trial evaluated the safety and preliminary efficacy of nonarmored GCC-targeted CAR T-cell therapy in 24 heavily pretreated metastatic colorectal cancer patients.
Platelet-rich plasma versus corticosteroid injections for facet and sacroiliac joint pain: a systematic review and meta-analysis with trial sequential analysis.
This systematic review and meta-analysis evaluated the efficacy of platelet-rich plasma (PRP) versus corticosteroid injections for treating facet and sacroiliac joint pain in 392 patients.
Family-Centered Child Obesity Treatment: The TEAM UP Randomized Clinical Trial.
This pragmatic randomized clinical trial evaluated the effectiveness of enhanced standard of care with family-based behavioral treatment (ESOC+FBT) compared to enhanced standard of care alone (ESOC) in reducing percent…
Erythropoietin for Neonatal Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.
This multicenter randomized clinical trial evaluated the efficacy of erythropoietin (EPO) as an adjunct to therapeutic hypothermia in infants with moderate to severe hypoxic-ischemic encephalopathy (HIE).
Treatment of Multifood Allergy With Omalizumab or Multiallergen Oral Immunotherapy: A Randomized Clinical Trial.
This randomized clinical trial compared the efficacy of omalizumab versus multiallergen oral immunotherapy (MOIT) in treating multifood allergies in participants aged 1 to 55 years.
Irritability in the Mix: An Exploratory Study of the Role of Irritability in Characterising Mood Disorders.
This randomized controlled trial explored the relationship between irritability and mixed states in 82 patients with bipolar disorder over 18 months.
A double-blind multi-centre randomised placebo-controlled trial of doxycycline in women with recurrent miscarriage and chronic endometritis defined by CD138 positive stromal cells.
This multicenter, double-blind, randomized controlled trial evaluated the effect of preconceptual doxycycline on live birth rates in women with recurrent miscarriage and chronic endometritis defined by CD138 positive…
Health Communication and Stepped Reminders Interventions for Lung Cancer Screening: A Randomized Clinical Trial.
This randomized clinical trial evaluated two patient-centered interventions aimed at increasing adherence to annual lung cancer screening among patients with normal findings.
Autonomous Oxygen Titration for Maintaining Normoxemia in Acutely Ill Adults: The SAVE-O2 AI Randomized Clinical Trial.
The SAVE-O2 AI randomized clinical trial evaluated the effectiveness of autonomous oxygen titration in maintaining normoxemia in acutely ill adults receiving supplemental oxygen.
The impact of unilateral endometriomas on ovarian response to stimulation: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the impact of unoperated unilateral endometriomas on ovarian response during stimulation cycles in women with endometriosis.
Histological Analysis Shows That a Moisturizer Formulated for Dermatoporosis Increases Elastin Content and Improves Skin Elasticity.
This multicenter clinical trial evaluated the effects of a novel moisturizer (GC cream) on skin biomarkers in individuals aged 40 to 60 with dermatoporosis.
Bone Accrual During Puberty Suppression and Gender-Affirming Therapy in Transgender Adolescents: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated bone mineral density (BMD) and z scores in transgender adolescents undergoing gonadotropin-releasing hormone agonist (GnRHa) therapy followed by gender-affirming…
Short-Term Effects of a Self-Monitoring-Based Intervention on Prolonged Sedentary Behavior in Older Adults With Cardiovascular Conditions: An Exploratory Secondary Analysis of a Randomized Controlled Trial.
This exploratory secondary analysis of a randomized controlled trial examined the impact of an accelerometer-guided self-monitoring intervention on prolonged sedentary behavior in older adults with cardiovascular…
Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence.
Two patients with chronic limb-threatening ischemia (CLTI) undergoing maintenance hemodialysis received concomitant Rheocarna therapy.
Balloon Enteroscopy-Assisted ERCP and EUS-Guided Biliary Drainage for Malignant Biliary Obstruction in Patients With Surgically Altered Anatomy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed balloon enteroscopy-assisted ERCP (BEA-ERCP) versus EUS-guided biliary drainage (EUS-BD) for malignant biliary obstruction in patients with surgically altered anatomy.
Iran's Escherichia coli AMR Landscape (2010-2025): A One Health Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the prevalence of antimicrobial resistance (AMR) in Escherichia coli across humans, animals, foods, and the environment in Iran from 2010 to 2025.
A Case of Primary Intramedullary Infantile Fibrosarcoma With an RBPMS::NTRK3 Fusion and Response to Larotrectinib.
A 4-week-old infant presented with rapidly progressive cervical myelopathy due to primary intramedullary infantile fibrosarcoma.
Tumor Profile, Clinical Features, and Outcomes in Individuals With Constitutional Trisomy 8: A Systematic Review of Case Reports and Case Series.
Constitutional trisomy 8 mosaicism (CT8M) is a rare chromosomal disorder with poorly characterized cancer risk. This systematic review aimed at summarizing reported cases of malignancy and associated clinical outcomes…
Mosaicism for Cohen-Gibson Syndrome in a Female Individual With Overgrowth and Neurodevelopmental Delay.
A 12-year-old girl presented with tall stature, dysmorphic features, developmental delay, and congenital anomalies. Genetic evaluation revealed a likely pathogenic mosaic variant in the EED gene, with varying allele…
Evolving Fetal Biometry in Fetal Intrahepatic Portosystemic Shunt With Late-Onset Preeclampsia and Focal Umbilical Cord Hypercoiling: A Case Report.
A pregnancy was evaluated at 26 + 3 weeks for suspected severe early-onset fetal growth restriction, with fetal weight below the 1st percentile. Imaging revealed a fetal intrahepatic portosystemic shunt.
Screening Strategies for Silent Myocardial Ischemia in Individuals With Diabetes Without Known Coronary Artery Disease: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of routine screening for silent myocardial ischemia in asymptomatic adults with diabetes and no known coronary artery disease.
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