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2000 articles

October 202624

Case ReportInfectious Diseases

Disseminated Bartonella or Post-Transplant Lymphoproliferative Disease in Pediatric Transplant Patients: A Diagnostic Challenge.

A pediatric kidney transplant patient presented with fever, lymphadenopathy, nausea, vomiting, and abdominal pain. An extensive workup for post-transplant lymphoproliferative disease (PTLD) was initiated, including PET…

Pediatr TransplantOct 1, 2026Read case
Clinical ResearchGeriatrics

Gut microbiome and healthy ageing: a systematic review of literature.

This systematic review examined the gut microbiome's compositional and functional features associated with healthy ageing, independent of age-related diseases.

Microbiology (Reading)Oct 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effect of Skin-To-Skin Contact During Caesarean Section on Pain and Stress in Newborns: A Randomized Controlled Trial.

This randomized controlled trial evaluated the impact of skin-to-skin contact during caesarean sections on neonatal pain and stress during the first intramuscular injection.

Nurs OpenOct 1, 2026Read summary
Clinical ResearchPsychiatry

Bipolar Disorder and Perimenopause: An Update.

This systematic review examined the relationship between bipolar disorder (BD) and perimenopause, analyzing 14 studies from various countries.

Bipolar DisordOct 1, 2026Read summary
Case ReportMedical Genetics

Hereditary Spastic Paraplegia Type 11: A Comprehensive Case Report.

An 18-year-old woman with no significant medical history presented with a 2-year history of progressive weakness and stiffness in both lower limbs, leading to difficulty in walking.

Mymensingh Med JOct 1, 2026Read case
Clinical ResearchGastroenterologyOpen access

Preoperative High-Dose Corticosteroids in Digestive Cancer Surgery: A Randomized Clinical Trial.

This multicenter, double-blind, placebo-controlled superiority randomized trial assessed whether preoperative high-dose corticosteroids improve outcomes after elective, curative-intent surgery for digestive cancer.

JAMA SurgOct 1, 2026Read summary
Clinical ResearchRheumatology

Bimekizumab efficacy in male and female patients with axial spondyloarthritis: 52-week results from the phase 3 BE MOBILE trials.

This post hoc analysis of two phase 3 randomised trials assessed sex-based differences in bimekizumab response among patients with radiographic or non-radiographic axial spondyloarthritis.

Rheumatology (Oxford)Oct 1, 2026Read summary
Case ReportRadiology (Diagnostic)

The Duke CSF-Venous Fistula Confidence Score: Real-World Application on CT Myelography.

A case of a patient with spontaneous intracranial hypotension was evaluated using CT myelography to identify a suspected CSF-venous fistula (CVF).

AJNR Am J NeuroradiolOct 1, 2026Read case
Case ReportUrology

Retroperitoneal urinoma presenting as a posterior knee sinus following emphysematous pyelitis.

A woman in her late 40s presented with abdominal sepsis due to emphysematous pyelitis and a retroperitoneal urinoma. Despite initial treatment, she developed persistent thigh pain and a posterior knee sinus.

BMJ Case RepOct 1, 2026Read case
Clinical ResearchPsychiatryOpen access

Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed randomised trials of psychological and psychosocial interventions targeting auditory hallucinations in adults with schizophrenia spectrum disorders.

JAMA PsychiatryOct 1, 2026Read summary
Clinical ResearchGeneral Surgery

Cross-Linked Chondroitin Sulfate Adhesion Barrier System in Open Rectal Resection: A Randomized Clinical Trial.

This multicenter, prospective, randomized, open-label trial with blinded endpoint assessment evaluated powdered cross-linked chondroitin sulfate (SI-449) in adults undergoing open rectal resection for rectal cancer.

JAMA SurgOct 1, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Incisional Negative Pressure Wound Therapy for Prevention of Surgical Site Infection: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled 85 randomised clinical trials involving 16,980 adults with primarily closed surgical incisions to compare incisional negative pressure wound therapy (iNPWT) with standard…

JAMA SurgOct 1, 2026Read summary
Clinical ResearchPsychiatry

Social Determinants of Health and Neurobiology Across the Schizophrenia Course: A Systematic Review.

This systematic review examined associations between adverse social determinants of health and brain measures in people across the schizophrenia spectrum, including those at elevated risk.

JAMA PsychiatryOct 1, 2026Read summary
Clinical ResearchNuclear MedicineOpen access

First-in-Human, Open-label, Single-Arm Phase I Study of [211At] meta-Astatobenzylguanidine in Patients with Pheochromocytoma or Paraganglioma.

This first-in-human, open-label, single-arm Phase I study evaluated the safety and pharmacokinetics of 211At-meta-astatobenzylguanidine (211At-MABG) in 10 patients with unresectable or metastatic pheochromocytomas or…

Clin Cancer ResOct 1, 2026Read summary
Clinical ResearchCardiologyOpen access

Diagnostic Accuracy of Circulating MicroRNAs for Coronary Artery Disease: An Updated Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic accuracy of circulating microRNAs (miRNAs) for coronary artery disease (CAD) in 3,879 participants across 24 studies.

J Cardiovasc Transl ResOct 1, 2026Read summary
Case ReportOrthopedic SurgeryOpen access

Modified tibiofibular synostosis vs. Burgess stump in a bilateral amputee: a case report.

A bilateral transtibial amputee had a modified tibiofibular synostosis (TFS) stump on the right and a conventional Burgess-type stump (BTS) on the left.

BMC Musculoskelet DisordOct 1, 2026Read case
Case ReportOphthalmology

Anterior Stromal Melt Following Implantation of a Large Size Corneal Allogenic Intrastromal Ring Segment (CAIRS).

To report delayed anterior stromal melt following corneal allogenic intrastromal ring segment (CAIRS) implantation in a patient without known systemic or ocular risk factors.

J Refract SurgOct 1, 2026Read case
Clinical ResearchRheumatology

First-line biologic and targeted synthetic DMARDs versus methotrexate in early rheumatoid arthritis: a meta-analysis of remission outcomes.

This systematic review and meta-analysis of randomized trials compared initial biologic and targeted synthetic DMARDs (b/tsDMARDs), alone or with methotrexate, against methotrexate in methotrexate-naïve adults with…

Rheumatology (Oxford)Oct 1, 2026Read summary
Case ReportHematology

Retrospective RNA Sequencing Reclassifies a Historical t(5;12) Eosinophilic Neoplasm From Presumed PDGFRB Rearrangement to ETV6::ACSL6.

A woman with a chronic eosinophilic myeloid neoplasm had a t(5;12) that raised suspicion of PDGFRB involvement, but contemporary testing did not identify a rearrangement and empiric imatinib produced no meaningful…

Genes Chromosomes CancerOct 1, 2026Read case
Clinical ResearchOncology (Medical)

Digital health interventions for psychological and cognitive care in cancer patients and caregivers: A RE-AIM-based systematic review.

This PRISMA-guided systematic review assessed the internal and external validity of digital interventions for psychological and cognitive concerns among people with cancer, caregivers, and family members, using the…

Appl Psychol Health Well BeingOct 1, 2026Read summary
Clinical ResearchGastroenterology

Effect of a Computer-Aided Device on Endoscopists' Biopsy Practice for Gastric Neoplasms: A Secondary Analysis of a Randomized Controlled Trial.

This secondary analysis of a randomized controlled trial compared AI-assisted with standard gastric screening, examining biopsy practice for documented lesions.

Dig EndoscOct 1, 2026Read summary
Clinical ResearchNeurology

Longitudinal clinical outcomes after amyloid clearance in aducanumab phase 3 studies.

This exploratory analysis pooled participants from the randomized phase 3 ENGAGE and EMERGE aducanumab trials who entered a long-term extension or later redosing study.

Alzheimers DementOct 1, 2026Read summary
Clinical ResearchGeneral Surgery

The Acceptability and Experiences of Participating in a Preoperative Intentional Weight-Loss Programme From Diagnosis to Surgery for Colorectal Cancer.

This qualitative study, embedded in the CARE randomised controlled trial, explored how patients with colorectal cancer experienced an intensive, dietitian-supported weight-loss programme between diagnosis and surgery.

Health ExpectOct 1, 2026Read summary
Clinical ResearchGeriatrics

Prevalence and Predictors of Depressive Symptom Trajectories in Older Adults: A Systematic Review.

This systematic review examined longitudinal patterns of depressive symptoms and their predictors among adults aged 60 years or older.

Brain BehavOct 1, 2026Read summary

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