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2000 articles
October 202624
Isolated Bilateral Periocular Lupus Miliaris Disseminatus Faciei: A Clinicopathological Mimicker of Granulomatosis With Polyangiitis.
A healthy young adult man presented with symmetrical papules confined to both periocular regions. Eyelid biopsy showed suppurative necrotizing granulomatous inflammation, prompting concern for granulomatosis with…
Characterizing Behavioral Engagement in Smartphone Cognitive Behavioral Therapy for Obsessive Compulsive Disorder: Secondary Analysis of a Randomized Controlled Trial.
This exploratory secondary analysis of a 12-week randomized controlled trial examined behavioral engagement with smartphone cognitive behavioral therapy for obsessive compulsive disorder (OCD) in 60 participants.
AI-Based Clinical Decision Support Systems in Primary Care: Systematic Review of Clinical Implementation.
This systematic review assessed the effectiveness and safety of AI-based clinical decision support systems (AI-CDSSs) used by health professionals in primary care, compared with usual care or non-AI decision support.
Walnut consumption improves mood and is associated with increased urinary excretion of 5-hydroxyindoleacetic acid and urolithins in a randomized crossover trial.
This 18-week open-label randomized crossover trial assessed whether daily walnut consumption affected mood and urinary metabolites in 31 healthy young adults.
Technological Integration in Triage With AI and Machine Learning Compared With Conventional Triage and Narrative Synthesis of Telehealth for Patient Prioritization in Emergency and Acute Care Settings: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed AI- and machine-learning-assisted triage alongside tele-triage and digital tools in emergency and acute care.
Incorporating Data From Text Messages and Email Into Psychotherapy: Randomized Controlled Trial.
This randomized controlled trial examined whether reviewing personalized text-message data before psychotherapy sessions improved outcomes for 101 adults and older adults receiving treatment for primary depression or…
Cerebrospinal fluid positive for SARS-CoV-2 associated with neurological manifestations and proteome alterations in a multiple myeloma patient.
A 67-year-old woman with multiple myeloma and recent exposure to a person with COVID-19 developed rapidly progressive dysarthria, dysphagia, and hypoesthesia without respiratory symptoms.
Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial.
This single-blind randomized controlled trial compared intraoral (IO) with extraoral (EO) photobiomodulation (PBM) to prevent oral mucositis in 155 children and adolescents receiving high-dose methotrexate for leukemia…
Metal Hypersensitivity Reactions Following Spinal Implants: A Systematic Review.
This systematic review examined clinical presentation, diagnostic approaches, and outcomes of metal hypersensitivity after spinal implant surgery in adults.
SARS-CoV2-induced Schnitzler syndrome, inflammatory flare and successful treatment by anakinra during pregnancy: a case report.
A pregnant woman in her early 40s with established Schnitzler syndrome developed urticaria, musculoskeletal symptoms and elevated inflammatory markers during SARS-CoV-2 infection, consistent with an inflammatory flare.
Descemet stripping only combined with cataract surgery and extended-depth-of-focus intraocular lens implantation: a surgical strategy and exploratory clinical evidence.
Three patients with Fuchs endothelial dystrophy, preserved peripheral endothelium, and visually significant cataract underwent combined Descemet stripping only, phacoemulsification, and implantation of a Vivity…
Effectiveness of physical, psychological, and alternative interventions for post-COVID-19 condition: a systematic review.
This systematic review of randomized controlled trials assessed supervised, face-to-face non-pharmacological interventions in adults with WHO-defined post-COVID-19 condition.
Efficacy and safety of ifupinostat in relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase 2 study.
This multicenter, single-arm phase 2 study evaluated intravenous ifupinostat monotherapy in patients with relapsed or refractory diffuse large B-cell lymphoma after at least two prior systemic therapy lines.
Pacak-Zhuang syndrome with EPAS1 p.Pro531Leu somatic variant: one case report and literature review.
A 4-year-old girl presented with recurrent hypertension, polycythemia and renal hilar masses. Imaging, biochemical testing and genetic analysis of paraffin-embedded tissue confirmed Pacak-Zhuang syndrome with a somatic…
Outdoor cycling competence and balance control in older adults - cross-sectional analysis of the BiPerAge trial.
This exploratory cross-sectional analysis used baseline data from a two-center randomized controlled trial to examine balance and outdoor cycling competence in 116 community-dwelling adults aged ≥ 65 years who made at…
Clinical Recovery Following Conservative Management of a Large Presumed Brain Abscess with a Concomitant Streptococcus intermedius Lung Abscess in a Severely Malnourished Young Adult in a Resource-Limited Setting: A Case Report.
A severely malnourished 22-year-old man presented with progressive left-sided weakness after weeks of productive cough, fever, and weight loss. Examination showed impaired consciousness and flaccid hemiplegia.
The Impact of Anaesthesia Method on the Use of Anaesthesia Department Resources in Total Knee Arthroplasty.
This randomised controlled trial compared spinal anaesthesia with general anaesthesia using total intravenous anaesthesia in 395 patients undergoing total knee arthroplasty.
Advances in physiotherapy for chronic low-back pain: a level I systematic review.
This level I systematic review qualitatively examined randomised controlled trials of physiotherapy programmes for chronic low-back pain (cLBP), identified through searches of PubMed, Web of Science and Embase in August…
An Integrated Approach to MSI-High Colorectal Cancer Therapy in a Young Patient: A Clinical Case.
A 16-year-old male underwent appendectomy for presumed appendicitis, but persistent postoperative bowel obstruction led to CT detection of a descending-colon tumor and emergency Hartmann’s procedure.
Full-spectrum LED screen-bar lighting as an adjunct to artificial tears in visual display terminal-related dry eye: a randomized study.
This prospective, randomised, single-centre study assessed whether full-spectrum screen-bar lighting adds benefit to artificial tears in 66 participants with newly diagnosed visual display terminal-related dry eye and…
Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects.
This open-label, randomized, single-dose, three-period crossover study compared the pharmacokinetics and safety of 20 mg zastaprazan orally disintegrating tablets (ODTs), taken with or without water, with the…
Magnetic resonance imaging vs computed tomography for baseline imaging evaluation in acute basilar artery occlusion.
This post hoc analysis of the ATTENTION trial compared baseline MRI with CT for patient selection in acute basilar-artery occlusion.
Hepatitis A Virus (HAV) Recurrence and De Novo Hepatitis A Acquired at Time of Liver Transplantation: Comparison of Graft HAV Infection and Viral Kinetics.
Two liver transplant recipients developed hepatitis A virus (HAV) infection of the graft in different settings. A recipient transplanted for HAV-related acute liver failure had a rapid fall in serum HAV RNA after…
Global cognitive and verbal episodic memory impairment in the post-acute phase of anti-nmdar encephalitis: a systematic review and meta-analysis with narrative synthesis.
This systematic review and meta-analysis examined standardized cognitive outcomes in adults with cell-based-assay-confirmed anti-NMDAR encephalitis during the post-acute or convalescent phase.
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