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2000 articles

October 202624

Clinical ResearchPediatrics

Prevalence and genotype distribution of norovirus and rotavirus among children under five with diarrheal infection in lower-middle-income countries after Rotavirus vaccine introduction: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed norovirus and rotavirus prevalence and genotype distribution among children under five with diarrheal infection in low- and middle-income countries after rotavirus…

PLoS OneOct 13, 2026Read summary
Clinical ResearchPulmonology

Machine Learning, Radiomics, and Clinical Models Predicting Checkpoint Inhibitor Pneumonitis in Lung Cancer: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed machine-learning, radiomics, deep-learning, and clinical models for predicting checkpoint inhibitor pneumonitis in people with lung cancer.

J Vis ExpOct 13, 2026Read summary
Clinical ResearchCardiology

Effect of diet-induced plasma ceramide on human in vivo microvascular endothelial function.

This double-blind, randomized crossover trial examined whether a meal-induced rise in plasma ceramides impairs in vivo microvascular function in 23 healthy young adults.

Am J Physiol Heart Circ PhysiolOct 13, 2026Read summary
Case ReportCardiology

Life-Threatening Ventricular Tachycardia and Transient Brugada-Like Electrocardiographic Abnormalities Caused by Severe Hyperkalemia Due to Urinary Retention in a 55-Year-Old Man.

A 55-year-old man without known cardiovascular disease presented with palpitations, dyspnea, and diaphoresis, then developed hemodynamically unstable sustained wide-QRS ventricular tachycardia with recurrent episodes…

Am J Case RepOct 13, 2026Read case
Clinical ResearchCardiology

Early Discharge Strategy Including Subcutaneous Furosemide in Hospitalized Heart Failure.

This multicenter, open-label, randomized active-controlled trial in the United Kingdom studied 172 patients hospitalized with heart failure who still required parenteral diuretics.

J Am Coll CardiolOct 13, 2026Read summary
Case ReportGastroenterology

PTCD and Peroral Electronic Cholangioscopy with Holmium Laser Lithotripsy for CBD Stones in a Super-Elderly Patient Post-Billroth II Gastrojejunostomy.

The management of impacted common bile duct stones in patients with prior Billroth II gastrectomy poses unique challenges. Altered gastrointestinal anatomy renders duodenoscope passage and biliary cannulation during…

J Vis ExpOct 13, 2026Read case
Case ReportPhysical Medicine & RehabilitationOpen access

Integrated physical, cognitive and psychological rehabilitation following multiple ACL reconstructions in a professional handball player: a case report.

A 31-year-old professional handball player with two ACL reconstructions, meniscal repairs, a postoperative knee infection, and multiple arthroscopic procedures had persistent knee instability, pain, and psychological…

J Med Case RepOct 13, 2026Read case
Clinical ResearchInfectious Diseases

The dual burden of disease: Depression among patients with multidrug resistance tuberculosis in low-income and lower- middle-income countries: A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated depression prevalence and examined associated factors among patients with multidrug-resistant tuberculosis (MDR-TB) in low- and lower-middle-income…

PLoS OneOct 13, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review of Academic Performance and Well-Being in University Students.

This systematic review synthesized 11 observational, cross-sectional studies of female medical and health sciences students published between January 2014 and December 2024.

J Vis ExpOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Refining Home-Based Squat Training: The Role of Hip Adduction in Improving Neuromuscular Control for Clinically Diagnosed Patellofemoral Pain Syndrome.

This randomized controlled trial compared an 8-week home-based squat program with and without hip adduction in 30 participants with clinically diagnosed patellofemoral pain syndrome (PFPS); both groups also performed…

Med Sci MonitOct 13, 2026Read summary
Clinical ResearchCardiologyOpen access

Fibro-Inflammatory Signaling, Fibrosis, and Microvascular Ischemia as Convergent Translational Substrates of Sudden Cardiac Death in Hypertrophic Cardiomyopathy: A Systematic Review.

This systematic translational review examined whether fibro-inflammatory signaling, fibrosis, and microvascular ischemia converge as substrates for ventricular arrhythmia and sudden cardiac death in hypertrophic…

J Cardiovasc Transl ResOct 13, 2026Read summary
Clinical ResearchInfectious Diseases

Epigenetic insights into anti-tuberculosis drug-induced liver injury: A systematic review of DNA methylation as a potential biomarker.

This systematic review assessed whether DNA methylation patterns are associated with susceptibility to anti-tuberculosis drug-induced liver injury (ATDILI).

Eur J PharmacolOct 13, 2026Read summary
Clinical ResearchCardiologyOpen access

Cold and Room-Temperature Platelets in Cardiac Surgery: The CHIPS Randomized Clinical Trial.

The phase 3, multicenter, randomized CHIPS trial compared cold-stored platelets (CSPs; up to 21 days) with room-temperature platelets (RTPs; up to 7 days) in pediatric and adult patients receiving platelet transfusions…

JAMAOct 13, 2026Read summary
Clinical ResearchDermatology

Clinical translation of polymeric microneedles for bioactive nanovesicle delivery in hypertrophic scar remodeling.

This prospective, single-center, open-label, single-arm study evaluated a 12-week protocol combining microplasma radiofrequency, poly(L-lactic acid) microneedles, and topical milk-derived bioactive nanovesicles in 26…

Biomater SciOct 13, 2026Read summary
Case ReportCardiology

Bee Sting-Associated Kounis Syndrome Presenting as Myocardial Infarction: A Case Report and Systematic Review with Age-Based Analysis.

A 44-year-old man presented with myocardial infarction after a probable bee sting-associated allergic reaction and was considered to have Kounis syndrome, an acute coronary syndrome linked to hypersensitivity.

Turk Kardiyol Dern ArsOct 13, 2026Read case
Clinical ResearchNeurologyOpen access

Pharmacological and Non-Pharmacological approaches to manage Tension-Type Headache: a Systematic Review.

This systematic review assessed randomized clinical trials of pharmacological and non-pharmacological treatments for episodic or chronic tension-type headache (TTH), examining headache pain and related clinical…

Curr Pain Headache RepOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Factors associated with 1-year health-related quality of life after neck-specific exercise in chronic whiplash-associated disorders: an exploratory secondary analysis of a randomized controlled trial.

This exploratory secondary analysis of a prospective, assessor-blinded, multicentre randomised trial examined factors associated with health-related quality of life (HRQoL) after neck-specific exercise in 140 people…

BMC Musculoskelet DisordOct 13, 2026Read summary
Clinical ResearchPsychiatry

Predicting IGD treatment outcomes across interventions using a whole-brain functional connectome biomarker.

This clinical trial study examined whether resting-state whole-brain functional connectivity could predict symptom improvement in 90 individuals with internet gaming disorder (IGD) receiving mindfulness meditation…

Dialogues Clin NeurosciOct 12, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Stereotactic body radiotherapy versus conventional external beam radiotherapy for bone metastases: a meta-analysis.

This systematic review and meta-analysis compared stereotactic body radiotherapy (SBRT) with conventional external beam radiotherapy (cEBRT) for painful bone metastases, pooling comparative clinical studies using…

Clin Exp MetastasisOct 12, 2026Read summary
Clinical ResearchUrologyOpen access

Robot-assisted ileal ureter replacement for complex ureteral strictures: a systematic review and single-arm meta-analysis of surgical and functional outcomes.

This systematic review and single-arm meta-analysis assessed surgical and functional outcomes after robot-assisted ileal ureter replacement (RIUR) in adults with complex ureteral strictures.

J Robot SurgOct 12, 2026Read summary
Clinical ResearchOncology (Medical)

Continuous intrathecal therapy for refractory cancer pain: A systematic review and meta-analysis focusing on partially implanted devices.

This systematic review and meta-analysis assessed partially implanted intrathecal devices (PIDs) for adults with refractory cancer-related pain, comparing them with conventional medical management and, in comparative…

Acta OncolOct 12, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Dynamics and functional heterogeneity of FOXP3+ regulatory T cells in Trypanosoma cruzi infection: a systematic review.

This systematic review synthesised 27 studies of FOXP3+ regulatory T-cell (Treg) phenotype and function in human and experimental Trypanosoma cruzi infection: 9 human studies and 18 murine studies.

Inflamm ResOct 12, 2026Read summary
Clinical ResearchCardiology

Blood pressure targets in adults with hypertension.

This publication is a protocol for a Cochrane intervention review, not a report of completed results. It sets out to assess lower blood pressure targets (≤ 135/85 mmHg) versus standard targets (≤ 140 to 160/90 to 100…

Cochrane Database Syst RevOct 12, 2026Read summary
Clinical ResearchPlastic SurgeryOpen access

Anatomical variation in the cervical branch of the facial nerve: a systematic review.

There is a paucity of literature on the anatomical variations of the cervical branch of the facial nerve (CBFN). Poor awareness of its anatomy and variations risks intraoperative damage, misdiagnosis of facial nerve…

Surg Radiol AnatOct 12, 2026Read summary

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