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2000 articles

October 202624

Clinical ResearchInfectious Diseases

Meta-analysis of Maternal and Fetal Outcomes of Crimean-Congo Hemorrhagic Fever during Pregnancy.

This meta-analysis examined the maternal and fetal outcomes of Crimean-Congo hemorrhagic fever (CCHF) in 55 pregnancies. The study found a maternal mortality rate of 28.8% and a fetal loss rate of 57.4%.

Emerg Infect DisOct 1, 2026Read summary
Clinical ResearchEndocrinology

Pharmacokinetic and Pharmacodynamic Drug-Drug Interactions Between Cofrogliptin and Metformin in Healthy Subjects: A Single-Center, Single-Arm, Phase I Study in China.

This single-center, single-arm Phase I study assessed drug-drug interactions between cofrogliptin and metformin in 22 healthy Chinese subjects.

Clin Pharmacol Drug DevOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

A Phase I Study of Nimotuzumab Combined with Irinotecan in Chinese Patients with Advanced Solid Tumors.

This Phase I study assessed the pharmacokinetics and safety of nimotuzumab combined with irinotecan in Chinese patients with advanced solid tumors.

Clin Pharmacol Drug DevOct 1, 2026Read summary
Case ReportPediatrics

Black Pleural Effusion as a Rare Presentation of Serotype 3 Pneumococcal Empyema.

A previously healthy 6-year-old boy presented with severe pneumonia, leading to the discovery of a black pleural effusion during thoracentesis.

PediatricsOct 1, 2026Read case
Clinical ResearchOncology (Medical)

Intermittent Pneumatic Compression in Patients with Postmastectomy Lymphedema: A Randomized Controlled Trial.

This randomized controlled trial evaluated the effects of intermittent pneumatic compression (IPC) combined with exercises on upper limb lymphedema in 21 patients post-mastectomy.

Mymensingh Med JOct 1, 2026Read summary
Case ReportUrology

Retroperitoneal urinoma presenting as a posterior knee sinus following emphysematous pyelitis.

A woman in her late 40s presented with abdominal sepsis due to emphysematous pyelitis and a retroperitoneal urinoma. Despite initial treatment, she developed persistent thigh pain and a posterior knee sinus.

BMJ Case RepOct 1, 2026Read case
Case ReportOncology (Medical)

Presentation and management of tislelizumab induced toxic optic neuropathy.

A woman with metastatic lung adenocarcinoma developed painless, progressive bilateral visual blurring after receiving second-line treatment with gemcitabine, carboplatin, and tislelizumab.

BMJ Case RepOct 1, 2026Read case
Clinical ResearchGeriatrics

Association of Sarcopenia With Global, Motor, Cognitive, and Swallowing Function Prognosis in Stroke Patients: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of sarcopenia on functional outcomes in stroke patients. Analyzing 36 cohort studies, it found that patients with sarcopenia had a significantly higher risk…

Brain BehavOct 1, 2026Read summary
Case ReportNeurosurgery

A Mysterious Case of Giant Scalp Devil's Horn with Intracranial Extension Removed by Surgical Excision.

A 60-year-old male presented with altered consciousness, chronic headaches, blurred vision, and scalp swelling. Imaging revealed a giant cutaneous horn in the scalp with underlying bony erosion and intracranial…

Mymensingh Med JOct 1, 2026Read case
Case ReportOncology (Medical)

Primary tongue leiomyosarcoma.

A male patient in his mid 50s presented with a non-healing ulcer on the right lateral border of the tongue, accompanied by impaired tongue movement.

BMJ Case RepOct 1, 2026Read case
Clinical ResearchNephrology

Mediation Analysis of Urine Osmolality and Response to Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Assessment.

This post hoc analysis of the TEMPO 3:4 randomized controlled trial evaluated urine osmolality (Uosm) as a biomarker for long-term response to tolvaptan in patients with autosomal dominant polycystic kidney disease…

Nephrology (Carlton)Oct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Anti-Angiogenic Tyrosine Kinase Inhibitors for Recurrent or Metastatic Nasopharyngeal Carcinoma: A Systematic Review and Single-Arm Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic tyrosine kinase inhibitors in 357 patients with recurrent or metastatic nasopharyngeal…

Cancer MedOct 1, 2026Read summary
Case ReportMedical Genetics

Hereditary Spastic Paraplegia Type 11: A Comprehensive Case Report.

An 18-year-old woman with no significant medical history presented with a 2-year history of progressive weakness and stiffness in both lower limbs, leading to difficulty in walking.

Mymensingh Med JOct 1, 2026Read case
Case ReportInfectious Diseases

Tuberculosis and persistent chylous ascites.

A late adolescent boy presented with fever, weight loss, and lymphadenopathy, leading to a diagnosis of extrapulmonary tuberculosis.

BMJ Case RepOct 1, 2026Read case
Case ReportGastroenterology

Gastric neuroendocrine tumours after prolonged proton pump inhibitor use.

A woman in her 40s with chronic gastro-oesophageal reflux disease had been on proton pump inhibitors for 20 years. She was diagnosed with gastric neuroendocrine tumours during an upper endoscopy.

BMJ Case RepOct 1, 2026Read case
Case ReportInfectious Diseases

Chlamydia psittaci Meningitis, Chile, 2023.

A 50-year-old farm worker in Chile presented with meningitis, which was confirmed to be caused by Chlamydia psittaci through cerebrospinal fluid quantitative real-time PCR and serology.

Emerg Infect DisOct 1, 2026Read case
Clinical ResearchEndocrinology

Effect of a walnut-based low carbohydrate diet on fat redistribution and visceral fat accumulation in people with central obesity: A randomized controlled trial.

This randomized controlled trial investigated the effects of a walnut-based low carbohydrate diet (w-LCD) on fat redistribution and visceral fat accumulation in individuals with central obesity over 12 weeks.

Asia Pac J Clin NutrOct 1, 2026Read summary
Case ReportNeurology

Acute Motor and Sensory Axonal Neuropathy Variant of Guillain-Barré Syndrome: A Nurse-Led Intensive Care Case Report.

A 40-year-old man presented with acute quadriparesis and respiratory distress after a febrile illness. He was diagnosed with acute motor and sensory axonal neuropathy, complicated by multiple infections including…

Crit Care NurseOct 1, 2026Read case
Clinical ResearchPediatrics

Spread and Sustainability of an Antimicrobial Stewardship Initiative Within a Pediatric Network.

This randomized controlled trial evaluated the sustainability of an antimicrobial stewardship initiative in a pediatric network, focusing on prescribing practices for skin and soft tissue infections (SSTI).

PediatricsOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Giredestrant plus Everolimus in Advanced Breast Cancer.

This phase 3 randomized controlled trial evaluated the efficacy of giredestrant plus everolimus versus standard endocrine therapy plus everolimus in patients with ER-positive, HER2-negative advanced breast cancer who…

N Engl J MedOct 1, 2026Read summary
Clinical ResearchHematology

Rilzabrutinib, an oral Bruton tyrosine kinase inhibitor, in patients with warm autoimmune haemolytic anaemia: a prospective, single-arm, multicentre, phase 2b safety and clinical activity study (LUMINA 2).

The LUMINA 2 study evaluated the safety and clinical activity of rilzabrutinib, a Bruton tyrosine kinase inhibitor, in adults with warm autoimmune haemolytic anaemia.

Lancet HaematolOct 1, 2026Read summary
Case ReportEndocrinology

Insights into diagnosis and management of giant adrenal pseudocysts.

A young man presented with headaches and mild anaemia, leading to imaging that revealed a giant left adrenal cystic lesion measuring 19×15×15 cm. Despite indeterminate CT findings, PET imaging suggested a benign nature.

BMJ Case RepOct 1, 2026Read case
Case ReportUrology

Primary malignant mesothelioma of the tunica vaginalis presenting as hydrocele: imaging pitfalls.

A man in his late 70s presented with a progressive, painless scrotal swelling initially diagnosed as a simple hydrocele via ultrasound.

BMJ Case RepOct 1, 2026Read case
Case ReportDermatology

Paraneoplastic dermatomyositis preceding detection of metastatic oesophageal squamous cell carcinoma after prolonged remission following pembrolizumab therapy.

A man in his late fifties with a history of treated oesophageal squamous cell carcinoma developed severe dermatomyositis after six years of remission.

BMJ Case RepOct 1, 2026Read case

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