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2000 articles

September 202624

Clinical ResearchPsychiatry

Epigenetic Programming of Stress-Response Systems: A Systematic Review of How Early Life Stress Shapes Developmental Trajectories of Mental Health.

This systematic review examines how early life stress (ELS) influences mental health development through epigenetic mechanisms, particularly DNA methylation, in 14 empirical human studies.

Dev PsychobiolSep 29, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Combined repetitive transcranial magnetic stimulation and mirror therapy for upper limb rehabilitation in stroke survivors: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of combined repetitive transcranial magnetic stimulation (rTMS) and mirror therapy (MT) on upper limb rehabilitation in stroke survivors.

Neurol SciSep 29, 2026Read summary
Case ReportNeurosurgery

Purely transvenous treatment of cervical paraspinal arteriovenous fistulas.

This report details two patients with paraspinal arteriovenous fistulas (PSAVF) treated using a purely transvenous approach.

Ideggyogy SzSep 29, 2026Read case
Clinical ResearchRadiology (Diagnostic)

Feasibility of deep learning reconstruction algorithm combined with the "ultra triple-low" protocol at 60 kVp in CTPA: An image quality and radiation dose assessment.

This randomised controlled trial assessed whether deep learning reconstruction could support pulmonary CT angiography using 60 kVp, 10 ml of iodine contrast, and a 2.5 ml/s injection rate.

Eur J RadiolSep 29, 2026Read summary
Case ReportDermatology

Genital lichen sclerosus with complete introital obliteration presenting with chronic urinary retention.

A postmenopausal woman with hypothyroidism presented with chronic urinary retention caused by complete introital obliteration due to lichen sclerosus.

BMJ Case RepSep 29, 2026Read case
Clinical ResearchGastroenterologyOpen access

Diagnostic yield of Franseen biopsy needles in endoscopic ultrasound-guided tissue acquisition: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic performance of Franseen biopsy needles compared to standard needles in endoscopic ultrasound-guided tissue acquisition among adult patients.

PeerJSep 29, 2026Read summary
Clinical ResearchNeurology

Lacosamide effects on pain management in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled clinical trial.

This randomized, double-blind, placebo-controlled trial assessed lacosamide for moderate-to-severe MS-related pain in adults with definite multiple sclerosis.

Mult Scler Relat DisordSep 29, 2026Read summary
Case ReportInfectious Diseases

Genomic evidence implicates patient-room showers in Mycobacterium llatzerense bacteremia among two cord blood transplant recipients.

Two cord blood transplant recipients developed persistent fever despite broad-spectrum therapy, with blood cultures eventually growing acid-fast bacilli. Sequencing identified Mycobacterium llatzerense.

J Infect ChemotherSep 29, 2026Read case
Case ReportNephrology

Peritoneal dialysis-associated peritonitis caused by Brevundimonasaurantiaca.

A 55-year-old man with end-stage kidney disease receiving continuous ambulatory peritoneal dialysis developed peritonitis, with Brevundimonas aurantiaca recovered from two consecutive effluent cultures.

J Infect ChemotherSep 29, 2026Read case
Case ReportOphthalmology

Autologous rotational partial thickness scleral flap - A salvage technique for late leaking blebs with scleral fistula.

Two patients with late leaking blebs complicated by scleral fistulae underwent a modified autologous rotational partial-thickness scleral flap procedure.

Indian J OphthalmolSep 29, 2026Read case
Clinical ResearchPediatricsOpen access

Oral glucose solution for the treatment of persistent asymptomatic neonatal hypoglycemia: a randomized, double-blind, placebo-controlled trial.

This multicenter, randomized, double-blind, placebo-controlled trial evaluated the efficacy of buccal 50% dextrose solution (D50W) in treating persistent asymptomatic hypoglycemia in at-risk late preterm and term…

Eur J PediatrSep 29, 2026Read summary
Clinical ResearchOncology (Medical)

Heart rate variability suppression in cancer patients versus non-cancer controls: a systematic review and meta-analysis.

This systematic review and meta-analysis examined heart rate variability (HRV) in cancer patients compared to non-cancer controls, including 28 studies with 3232 participants.

Support Care CancerSep 29, 2026Read summary
Clinical ResearchAllergy & Immunology

Short-term nasal decongestant as bridge therapy with intranasal corticosteroids in children with persistent allergic rhinitis: A randomized controlled trial.

This prospective, open-label, single-centre randomised trial compared intranasal corticosteroid (INS) alone with INS plus five days of oxymetazoline in children aged 4–17 years with moderate-to-severe persistent…

Int J Pediatr OtorhinolaryngolSep 29, 2026Read summary
Case ReportNeurology

Neurosyphilis Concurrently Presenting With Limbic Encephalitis and Normal Pressure Hydrocephalus: A Case Report.

A 47-year-old man presented with cognitive decline, gait disturbance, and urinary incontinence. Imaging revealed ventricular enlargement and high signal intensity in the medial temporal lobes.

Neuropsychopharmacol RepSep 29, 2026Read case
Clinical ResearchObstetrics & Gynecology

Associations between prenatal bisphenol S with gestational age and preterm birth: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether prenatal bisphenol S (BPS) exposure is associated with gestational age or preterm birth.

Environ ResSep 29, 2026Read summary
Case ReportMedical Genetics

Longest surviving patient with a homozygous splice-altering EGFR pathogenic variant presenting with skin autoinflammation and a Bartter-like salt-losing tubulopathy.

An adolescent patient with a Bartter-like phenotype presented with progressive nephrocalcinosis, hypercalciuria, and skin autoinflammation.

J Med GenetSep 29, 2026Read case
Case ReportCardiology

Iatrogenic Large Bowel Perforation Following Image-Guided Pericardiocentesis: A Case Report.

A 72-year-old man with multiple comorbidities underwent fluoroscopy-guided pericardiocentesis for a large pericardial effusion.

Am J Case RepSep 29, 2026Read case
Case ReportMedical GeneticsOpen access

Severe neurodevelopmental phenotype with multisystem involvement in VPS16-related mucopolysaccharidosis-like syndrome.

A patient with biallelic VPS16 variants presented with profound developmental delay, early-onset epilepsy, and spasticity, alongside multisystem issues such as recurrent infections and neutropenia.

NeurogeneticsSep 29, 2026Read case
Clinical ResearchCardiology

Vascular effects of dietary nitrate supplementation in older adults with coronary artery disease: A randomized, placebo-controlled, crossover pilot trial.

This randomized, double-blind, placebo-controlled crossover pilot trial assessed the safety, feasibility, and vascular effects of beetroot-derived dietary nitrate in eight older adults with confirmed coronary artery…

Exp GerontolSep 29, 2026Read summary
Clinical ResearchPulmonology

Effects of pulmonary rehabilitation on lung hyperinflation in patients with COPD: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether pulmonary rehabilitation (PR) affects static and dynamic lung hyperinflation in people with COPD.

Respir MedSep 29, 2026Read summary
Clinical ResearchInfectious Diseases

Real-world evaluation of 2023-2024 XBB.1.5 mRNA and protein-based COVID-19 vaccine reactogenicity from the randomized BEEHIVE trial.

This randomized controlled trial evaluated the reactogenicity of the 2023-2024 XBB.1.5 mRNA and protein-based COVID-19 vaccines in participants with prior mRNA vaccination.

Hum Vaccin ImmunotherSep 29, 2026Read summary
Case ReportOphthalmology

Bilateral Vortex Keratopathy in a Patient Receiving Long-Term Ribociclib Therapy.

A 67-year-old woman with metastatic breast cancer was found on routine eye examination to have bilateral whorl-like corneal epithelial deposits after four years of continuous ribociclib therapy.

Eye Contact LensSep 29, 2026Read case
Clinical ResearchInfectious Diseases

Exploring the relationship between HIV Testing frequency and sexual behavior, prevention prophylaxis use among MSM in Southern China.

This randomized controlled trial investigated the relationship between HIV testing frequency, sexual behaviors, and prophylaxis use among 327 men who have sex with men (MSM) in Guangxi, China.

PLoS OneSep 29, 2026Read summary
Clinical ResearchPsychiatry

Exploring treatment moderators in a randomized clinical trial of virtual reality-based vs. standard cognitive behavioral therapy for paranoia.

This randomized clinical trial secondary analysis explored whether clinical and sociodemographic characteristics moderated response to virtual reality-based cognitive behavioral therapy for psychosis (VR-CBTp) versus…

Schizophr ResSep 29, 2026Read summary

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