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920 articles
October 202624
Unmasking Weakness: A Case of Pembrolizumab-induced Myasthenia Gravis With Concurrent Myositis.
An 86-year-old patient with renal cell carcinoma developed generalized weakness, dysphagia, dysphonia, eyelid ptosis, and ophthalmoparesis shortly after the second dose of pembrolizumab.
Recurrent Nodular Lymphocyte Predominant Hodgkin Lymphoma with Diagnostic Evolution Over Two Decades.
A 51-year-old man had a nearly 20-year history of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), with multiple relapses and prolonged remissions.
Parathyroid Hormone-related Peptide Is a Better Indicator of Cancer Treatment Efficacy Than Serum Calcium.
A 66-year-old woman with extensive cutaneous squamous cell carcinoma of the scalp, unsuitable for primary surgical removal, received cemiplimab.
Familial Glioma in a Father and Son: Integrated Genomic and Multi-compartment Proteomic Profiling.
A 60-year-old father and his 35-year-old son presented with gliomas. The father’s tumor was glioblastoma, IDH-wildtype, WHO grade 4, with an unmethylated MGMT promoter; the son’s was astrocytoma, IDH-mutant, WHO grade…
Abscopal-like Regression of Lung Metastases After Near-infrared Photoimmunotherapy Plus Nivolumab in Laryngeal Carcinoma.
A man in his 60s with recurrent laryngeal squamous cell carcinoma, base-of-tongue involvement, and multiple pulmonary metastases had progressed after several treatments, including platinum- and pembrolizumab-containing…
VITREOUS METASTASIS OF LARYNGEAL CARCINOMA PRESENTING AS A WHITE MASS: A CASE REPORT.
A 56-year-old man receiving immunochemotherapy for laryngeal carcinoma presented with two weeks of left-eye photopsia. Examination showed mild anterior chamber and vitreous cells, slight macular edema, and a white…
SUBRETINAL LAVAGE DURING DIAGNOSTIC VITRECTOMY: AN ADJUNCTIVE TECHNIQUE FOR CELL SAMPLING IN SUSPECTED VITREORETINAL LYMPHOMA.
In patients with suspected vitreoretinal lymphoma and predominant subretinal involvement, standard vitreous sampling may have limited sensitivity.
Zamtocabtagene autoleucel, a tandem CD20-CD19-directed CAR T-cell therapy, for second line treatment of large B-cell lymphoma in patients ineligible for transplantation (DALY 2-EU): primary analysis of an open-label, multicentre, randomised phase 2 study.
DALY 2-EU was an open-label, multicentre, randomised phase 2 trial comparing tandem CD20-CD19-directed zamtocabtagene autoleucel (zamto-cel) with R-GemOx in adults with second-line relapsed or refractory large B-cell…
Efficacy and Safety of Apixaban Thromboprophylaxis According to Baseline Chemotherapy Class in High-Risk Ambulatory Cancer Patients: A Post Hoc Analysis of the AVERT Trial.
This post hoc analysis of the randomized, double-blind AVERT trial examined apixaban thromboprophylaxis by baseline chemotherapy class in 563 ambulatory patients with cancer starting chemotherapy.
The role of tyrosine kinase inhibitors as a post-hematopoietic stem cell transplant continuation therapy for pediatric acute leukemia: a systematic review.
This systematic review assessed tyrosine kinase inhibitors (TKIs) as continuation therapy after hematopoietic stem cell transplantation (HSCT) in children with acute leukemia.
Protein-losing enteropathy as a rare presentation of small bowel T-cell post-transplant lymphoproliferative disease.
A kidney transplant recipient developed episodic diarrhea, with initial investigations showing no bowel pathology. She later developed fluid retention associated with hypoalbuminemia, and technetium-99m human serum…
Associating liver partition and portal vein ligation for staged hepatectomy procedure versus conventional two-stage hepatectomy for colorectal liver metastasis.
This Cochrane systematic review and meta-analysis assessed ALPPS versus conventional two-stage hepatectomy in adults with colorectal liver metastases and an estimated future liver remnant below 30% of total liver…
Safety and efficacy of dual immune checkpoint inhibition for melanoma brain metastases and its comparison to ICI monotherapy: A systematic review and meta-analysis.
This PRISMA-based systematic review and meta-analysis pooled prospective and retrospective studies of adults with cutaneous or mucosal melanoma brain metastases treated with dual immune checkpoint inhibition (ICI), and…
Body image distress in women and men with advanced pancreatic cancer approaching death - post-hoc analyses from the MISTRAL-trial.
This post-hoc analysis of data from the MISTRAL trial examined changes in body image distress and weight worries among 125 women and men with pancreatic cancer during the six months before death.
Long-term remission of severe psoriasis following CD19-directed chimeric antigen receptor T-cell therapy for follicular lymphoma.
A 60-year-old woman with a 49-year history of severe plaque psoriasis received autologous CD19-directed CAR-T therapy for follicular lymphoma.
Consequences of opioid exposure in disease-free cancer survivors: A systematic literature review.
This systematic literature review examined the consequences of persistent opioid exposure after curative-intent treatment in disease-free cancer survivors.
Sialadenopapillary Ductal Tumor: Case Series and Review of the Literature.
The authors describe three patients with sialadenopapillary ductal tumors, a rare neoplasm of likely minor salivary gland origin characterized by prominent submucosal ductal proliferation and multilayered cystic…
Oxalate Nephropathy in a patient with Neuroendocrine tumor receiving Long-acting Octreotide.
A 55-year-old man with metastatic somatostatin receptor-positive neuroendocrine tumour received long-acting octreotide and, later, four cycles of 177 Lu-DOTA-TATE peptide receptor radionuclide therapy (PRRT).
"What a beautiful gift, life": Dignity therapy and the making of a legacy in a patient with grade 4 glioblastoma.
A man in his mid-40s with grade 4 glioblastoma of the corpus callosum received psycho-oncological support from diagnosis, with parallel support for his caregiver.
Beyond denial: A case report illustrating the complexity of disengagement in advanced cancer care.
A woman in her forties from Africa with advanced metastatic gastric cancer declined prognostic discussions, did not want her family informed, and avoided opioid analgesia.
Previously Unrecognized Distinct Laryngeal Lesions During Lazertinib Therapy in EGFR-Mutated NSCLC: A Case Series.
Four patients with non-small cell lung cancer developed new voice changes or a globus sensation while receiving lazertinib-based therapy.
Prognostic associations between patient-reported outcomes and progression-free and overall survival in advanced gastric or gastroesophageal junction adenocarcinoma with PD-L1 TAP score ≥ 5%: results from the RATIONALE-305 trial.
This analysis of the randomised RATIONALE-305 trial examined whether longitudinal patient-reported outcomes (PROs) were associated with progression-free survival (PFS) and overall survival (OS) in patients with advanced…
Neoadjuvant short-course radiotherapy followed by camrelizumab and chemotherapy versus standard of care for locally advanced rectal cancer (UNION): a prespecified interim analysis of a multicentre, open-label, randomised, phase 3 trial.
UNION was a multicentre, open-label, randomised phase 3 trial at nine hospitals in China comparing neoadjuvant short-course radiotherapy followed by camrelizumab plus CAPOX with long-course chemoradiotherapy followed by…
Fatal Rickettsia parkeri Rickettsiosis in Immunocompromised Pediatric Patient, Georgia, USA, 2025.
A 3-year-old boy in Georgia, USA, receiving chemotherapy for B-cell acute lymphoblastic leukemia was hospitalized with febrile neutropenia.
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