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2000 articles
October 202624
A missense variant in LAMB3 underlies variable expressivity in familial tooth agenesis and microdontia.
A three-generation family presented with non-syndromic dental anomalies, including missing teeth (oligodontia), microdontia and delayed eruption.
MULTIMODAL IMAGING OF BENIGN LOBULAR INNER NUCLEAR LAYER PROLIFERATIONS.
A 10-year-old boy was evaluated for multiple whitish intraretinal lesions and widespread pigmented spots. Examination showed bilateral lesions at the posterior pole and midperiphery, alongside extensive grouped…
B cell subsets are associated with durable responses in distinct cancer types after immune checkpoint inhibition.
This study examined B-cell responses and outcomes after immune checkpoint inhibition, combining a prospective randomized phase 2 trial of 106 patients with single-cell profiling of intratumoral B cells from 152 patients…
Abscopal-like Regression of Lung Metastases After Near-infrared Photoimmunotherapy Plus Nivolumab in Laryngeal Carcinoma.
A man in his 60s with recurrent laryngeal squamous cell carcinoma, base-of-tongue involvement, and multiple pulmonary metastases had progressed after several treatments, including platinum- and pembrolizumab-containing…
Cranial and Spinal Epithelioid Hemangioma: Systematic Review and Illustrative Calvarial Case.
Cranial and neuraxial epithelioid hemangioma (EH) is exceptionally rare and anatomically heterogeneous. We systematically reviewed reported cerebral, cranial osseous, primary non-osseous spinal epidural, and…
HYDROXYCHLOROQUINE TOXICITY WITH SHORT DURATION OF HYDROXYCHLOROQUINE USE AND UNILATERAL BULL's EYE MACULOPATHY.
A 77-year-old Japanese woman presented with years of gradually worsening vision in her right eye. She had rheumatoid arthritis and had taken hydroxychloroquine 200 mg for five years, approximately 20 years earlier.
FLANGED INTRASCLERAL INTRAOCULAR LENS FIXATION USING 31-G NEEDLES.
A 73-year-old man with right intraocular lens (IOL) subluxation underwent flanged intrascleral IOL fixation using the double-needle technique with a 31-gauge needle.
TENON CAPSULE GRAFT AS A SEALANT IN PEDIATRIC RETINAL DETACHMENT.
The report describes four pediatric cases of complex retinal detachment associated with infantile high-myopic macular holes, Morning Glory Syndrome, or optic disk pit maculopathy.
IMPROVEMENT OF MACULOPATHY ASSOCIATED WITH CAVITARY OPTIC DISK ANOMALIES TREATED WITH TOPICAL ANTIGLAUCOMA MEDICATIONS.
Two young women developed worsening visual acuity associated with serous retinal detachment and maculopathy in the setting of cavitary optic disk anomalies.
Impact of acoramidis on clinical stability in transthyretin amyloid cardiomyopathy: observations from ATTRibute-CM.
This post-hoc analysis of the phase 3, multicentre, randomised ATTRibute-CM trial assessed clinically meaningful changes in NT-proBNP or 6-minute walk distance among participants with transthyretin amyloid…
Home-based nurse-led self-management support for heart failure: a randomized controlled trial.
This parallel-group randomized controlled trial assessed a 12-week, nurse-led home programme of tailored self-management support and follow-up for adults aged 40–75 years with NYHA class I–III heart failure and ejection…
INTRARETINAL SCLEROCHOROIDAL VESSELS IN EYES WITH SEVERE CHORIORETINAL THINNING: HYPOTHESIS ON BRUCH's MEMBRANE FAILURE.
A retrospective case series described six eyes with advanced chorioretinal thinning from varied causes, including pathologic myopia, iatrogenic staphyloma, chronic anti-VEGF exposure, and nonmyopic macular atrophy.
Efficacy and cost effectiveness of high volume injections with and without corticosteroid compared with sham for midportion Achilles tendinopathy (Inject trial): randomised controlled trial.
The Inject trial was a single-centre, participant- and assessor-masked, three-arm randomised controlled trial in 192 adults with midportion Achilles tendinopathy.
Parathyroid Hormone-related Peptide Is a Better Indicator of Cancer Treatment Efficacy Than Serum Calcium.
A 66-year-old woman with extensive cutaneous squamous cell carcinoma of the scalp, unsuitable for primary surgical removal, received cemiplimab.
Peritoneal Tuberculosis and Chronic Myeloid Leukaemia: A Case of Hickam's Dictum.
A 34-year-old man presented with persistent fever, ascites, thrombocytosis and clinical deterioration despite broad-spectrum therapy.
Catheter ablation in end-stage heart failure with atrial fibrillation: an hierarchical endpoint analysis of the CASTLE-HTx trial.
This ancillary hierarchical endpoint analysis of the multicentre randomized CASTLE-HTx trial compared catheter ablation plus guideline-directed medical therapy (GDMT) with medical therapy alone in 194 patients with…
BILATERAL PARACENTRAL ACUTE MIDDLE MACULOPATHY IN A PEDIATRIC PATIENT WITH SICKLE CELL DISEASE.
An 8-year-old boy with HbSS sickle cell disease and no previous sickle cell retinopathy developed blurred vision, headache, photopsia, and metamorphopsia during an influenza A-associated upper respiratory illness.
Robot-assisted versus open partial nephrectomy in patients with a solitary kidney: a systematic review and meta-analysis of perioperative and functional outcomes.
This systematic review and meta-analysis compared robot-assisted partial nephrectomy (RAPN) with open partial nephrectomy (OPN) for tumors in a solitary kidney.
Associating liver partition and portal vein ligation for staged hepatectomy procedure versus conventional two-stage hepatectomy for colorectal liver metastasis.
This Cochrane systematic review and meta-analysis assessed ALPPS versus conventional two-stage hepatectomy in adults with colorectal liver metastases and an estimated future liver remnant below 30% of total liver…
Evaluating treatment efficacy for Iliotibial Band Syndrome: A comparison of combined foam rolling and stretching with strengthening exercises versus strengthening alone in athletes.
This randomized controlled trial compared strengthening alone with strengthening plus foam rolling and stretching in 20 athletes with confirmed iliotibial band syndrome.
Diagnostic accuracy of high-sensitivity point-of-care troponin assays in emergency department for patients presenting with chest pain: a systematic review.
This systematic review assessed the diagnostic accuracy of four commercially available high-sensitivity point-of-care troponin assays in adults presenting to emergency departments with chest pain suggestive of acute…
Haemodynamic and Respiratory Effects of Dexmedetomidine as an Adjuvant to Oxycodone Patient-Controlled Analgesia After Lumbar Spinal Fusion: A Post Hoc Analysis of the DoseRespDex Randomised Controlled Trial.
This post hoc analysis of a randomised, double-blind, placebo-controlled trial examined haemodynamic and respiratory effects of dexmedetomidine added to oxycodone patient-controlled analgesia in 98 adults undergoing…
Efficacy and Safety of Apixaban Thromboprophylaxis According to Baseline Chemotherapy Class in High-Risk Ambulatory Cancer Patients: A Post Hoc Analysis of the AVERT Trial.
This post hoc analysis of the randomized, double-blind AVERT trial examined apixaban thromboprophylaxis by baseline chemotherapy class in 563 ambulatory patients with cancer starting chemotherapy.
Three-week ileostomy closure after colorectal surgery: a multicenter randomized trial of technical and postoperative outcomes.
This prospective multicenter randomized trial compared ileostomy closure at 3 weeks with conventional delayed closure in 224 patients after restorative colorectal resection.
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