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2000 articles
October 202624
Post-Stroke Depression and Determinants in Ethiopia; A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the prevalence and determinants of post-stroke depression (PSD) in Ethiopia, combining findings from eight studies.
Fibro-Inflammatory Signaling, Fibrosis, and Microvascular Ischemia as Convergent Translational Substrates of Sudden Cardiac Death in Hypertrophic Cardiomyopathy: A Systematic Review.
This systematic translational review examined whether fibro-inflammatory signaling, fibrosis, and microvascular ischemia converge as substrates for ventricular arrhythmia and sudden cardiac death in hypertrophic…
Safety and immunogenicity of Thailand Government Pharmaceutical Organization (GPO) produced, COVID-19 vaccine, 10 μg HXP-GPOVac: A Phase III, double-blind, randomized trial in comparison with VAXZEVRIA.
This phase III, double-blind, randomized active-controlled trial compared a single dose of Thailand-produced HXP-GPOVac with VAXZEVRIA in healthy or clinically stable Thai adults who had completed a two-dose COVID-19…
Atypical presacral masses in Currarino syndrome: a case series.
The report describes three patients with Currarino syndrome, a congenital condition involving a sacral anomaly, anorectal malformation, and presacral mass.
Successful Kidney Transplantation Under Combined Spinal-Epidural Anesthesia in a Patient With a History of Left Pneumonectomy Due to Bronchiectasis.
A 33-year-old man with end-stage kidney disease from biopsy-proven AA amyloidosis was assessed for preemptive living-donor kidney transplantation.
Pharmacological and Non-Pharmacological approaches to manage Tension-Type Headache: a Systematic Review.
This systematic review assessed randomized clinical trials of pharmacological and non-pharmacological treatments for episodic or chronic tension-type headache (TTH), examining headache pain and related clinical…
Hemi-see-saw nystagmus with superimposed pendular oculopalatal tremor: case report and systematic review.
A 30-year-old man with a pontomedullary arteriovenous malformation presented with pendular hemi-see-saw nystagmus, right one-and-a-half syndrome, gaze-evoked nystagmus, ocular tilt reaction, incomplete Horner syndrome…
Six-month supervised telerehabilitation combining pilates-based therapeutic exercise and self-myofascial release in adults with fibromyalgia: a randomized controlled trial.
This two-arm randomized controlled trial evaluated a six-month supervised home-based telerehabilitation programme in 68 adults with fibromyalgia confirmed by 2016 ACR criteria.
Stroke thrombectomy of a mural thrombus in a severe dolichoectatic basilar artery with double parallel large stent retrievers and Sofia 88.
An older adult presented with severe acute ischemic stroke from a mural thrombus on the posterior wall of the mid-basilar artery.
Daily Zinc Supplementation for Infection Prevention in Children With Sickle Cell Anemia: The ZIPS-2 Randomized Clinical Trial.
The ZIPS-2 randomized, double-blind, placebo-controlled trial evaluated daily zinc for infection prevention in children aged 1 to 4.99 years with sickle cell anemia in Uganda.
Elinzanetant in postmenopausal women with sleep disturbance: results from the randomized, phase II NIRVANA study.
The phase II NIRVANA randomised trial assessed elinzanetant versus placebo in 110 postmenopausal women aged 40–65 years with moderate-to-severe vasomotor symptoms and objectively measured sleep disturbance.
Epigenetic insights into anti-tuberculosis drug-induced liver injury: A systematic review of DNA methylation as a potential biomarker.
This systematic review assessed whether DNA methylation patterns are associated with susceptibility to anti-tuberculosis drug-induced liver injury (ATDILI).
Myeloid neoplasm with PDGFRA rearrangement presenting in blast-phase with basophilia.
An adult man from Southern Africa presented with progressive fatigue. Blood morphology showed marked basophilia and 21% myeloblasts, with flow cytometry supporting a provisional diagnosis of acute myeloid leukaemia with…
Comparative effects of non-pharmacological intervention categories on cognitive domains in children with autism spectrum disorder: A systematic review and network meta-analysis of randomized controlled trials.
This systematic review and network meta-analysis compared non-pharmacological intervention categories for cognitive outcomes in children with autism spectrum disorder, drawing on randomized controlled trials.
Prevalence and genotype distribution of norovirus and rotavirus among children under five with diarrheal infection in lower-middle-income countries after Rotavirus vaccine introduction: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed norovirus and rotavirus prevalence and genotype distribution among children under five with diarrheal infection in low- and middle-income countries after rotavirus…
Cost comparison of the ShangRing device versus Mogen clamp for early infant male circumcision in Sub-Saharan Africa.
This cost comparison alongside a randomized controlled trial assessed early infant male circumcision using the ShangRing (SR) versus the Mogen clamp (MoC) among infants aged 0–60 days in Kenya, Tanzania, and Uganda.
Successful management of long-term venovenous ECMO for severe PARDS in a child with acute lymphoblastic leukemia.
A 5-year-old boy with low-risk B-cell acute lymphoblastic leukemia developed severe, refractory pediatric acute respiratory distress syndrome during induction therapy, with profound hypoxemia.
Network Meta-Analysis: Treatments for Acute Alcohol-Associated Hepatitis.
This systematic review and network meta-analysis compared treatments for alcohol-associated hepatitis (AH) using 90-day survival as the primary outcome.
Early Discharge Strategy Including Subcutaneous Furosemide in Hospitalized Heart Failure.
This multicenter, open-label, randomized active-controlled trial in the United Kingdom studied 172 patients hospitalized with heart failure who still required parenteral diuretics.
Opioid-free versus opioid-based anesthesia for robot-assisted radical prostatectomy: a single-center randomized controlled trial.
This single-center randomized controlled trial compared opioid-free anesthesia (dexmedetomidine plus ketamine) with remifentanil-based anesthesia in adult men undergoing robot-assisted radical prostatectomy.
Integrated physical, cognitive and psychological rehabilitation following multiple ACL reconstructions in a professional handball player: a case report.
A 31-year-old professional handball player with two ACL reconstructions, meniscal repairs, a postoperative knee infection, and multiple arthroscopic procedures had persistent knee instability, pain, and psychological…
The dual burden of disease: Depression among patients with multidrug resistance tuberculosis in low-income and lower- middle-income countries: A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis estimated depression prevalence and examined associated factors among patients with multidrug-resistant tuberculosis (MDR-TB) in low- and lower-middle-income…
Impact of a Dynamic Visualized Pain Assessment Tool on Pediatric Pain Management: A Stepped-Wedge Cluster Randomized Trial.
This stepped-wedge cluster randomized trial evaluated a dynamic visualized pain assessment tool across five clinical wards, involving 15 infants and 45 video segments spanning baseline, procedural pain, and…
Factors associated with 1-year health-related quality of life after neck-specific exercise in chronic whiplash-associated disorders: an exploratory secondary analysis of a randomized controlled trial.
This exploratory secondary analysis of a prospective, assessor-blinded, multicentre randomised trial examined factors associated with health-related quality of life (HRQoL) after neck-specific exercise in 140 people…
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