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1566 articles
October 202624
Clinical utility of randomized controlled trials of regional anesthesia for lower-extremity surgery: a systematic review.
This systematic review evaluated the clinical utility and transparency of randomized controlled trials (RCTs) on regional anesthesia (RA) for lower-extremity surgeries.
Assessing the completeness of safety reporting in clinical trials of regional anesthesia interventions: a registry-publication comparison systematic review.
This systematic review evaluated the completeness of adverse event (AE) reporting in interventional regional anesthesia trials registered on ClinicalTrials.gov and their corresponding publications.
Feeding following cleft palate surgery: a prospective randomized clinical trial comparing suprazygomatic maxillary nerve block and greater palatine nerve block.
This randomized controlled trial evaluated the effectiveness of suprazygomatic maxillary nerve blocks (SZMNB) versus greater palatine nerve blocks (GPNB) in children aged 1-10 undergoing cleft palate surgery.
Objective, long-term mobility data in patients with chronic pain after lumbar spine surgery treated with spinal cord stimulation-a prospective, multicenter trial.
This multicenter clinical trial evaluated the long-term effects of spinal cord stimulation (SCS) on mobility in 50 patients with chronic pain following lumbar spine surgery.
Impact of opioid-free general anesthesia with locoregional blocks during breast cancer surgery on systemic inflammatory response: results from a randomized controlled trial.
This randomized controlled trial evaluated the effects of opioid-free general anesthesia with locoregional blocks (OfGA) versus traditional opioid-based general anesthesia (GA) on postoperative inflammation in breast…
Percutaneous coronary intervention using sirolimus-eluting balloons in patients at high bleeding risk: the SELUTION DeNovo HBR substudy.
The SELUTION DeNovo trial, a randomized controlled trial, evaluated sirolimus-eluting balloons (SEBs) versus drug-eluting stents (DES) in 522 high bleeding risk (HBR) patients.
Complexity of coronary artery disease in infarct-related cardiogenic shock and multivessel disease: a substudy of the DanGer Shock trial.
This study, a secondary analysis of the DanGer Shock trial, evaluated the prognostic significance of baseline and residual SYNTAX scores in 256 patients with multivessel disease and infarct-related cardiogenic shock.
Standardised versus visual assessment of device success after percutaneous coronary intervention.
This randomized controlled trial evaluated the alignment of operator-reported device success with standardized definitions using quantitative coronary angiography (QCA) in 1,548 patients undergoing percutaneous coronary…
Restorative resection in robot-assisted versus laparoscopic total mesorectal excision: systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the outcomes of robot-assisted total mesorectal excision (R-TME) versus laparoscopic total mesorectal excision (L-TME) in rectal cancer surgery, involving 7133 patients…
Integration of Virtual and Augmented Reality Into Obstetric Nursing and Midwifery Education: Systematic Review.
This systematic review evaluated the use of virtual reality (VR) and augmented reality (AR) in obstetric nursing and midwifery education, analyzing four studies with 634 participants.
Off-label palopegteriparatide for severe pediatric postsurgical hypocalcemia.
A 14-year-old boy with Graves’ disease developed profound hypocalcemia after total thyroidectomy, with serum calcium 5.9 mg/dL, ionized calcium 0.83 mmol/L, and undetectable parathyroid hormone.
SYSTEMATIC REVIEW AND BRAZILIAN EXPERT CONSENSUS ON THE USE OF BIOSIMILARS IN INFLAMMATORY BOWEL DISEASE: BRAZILIAN ORGANIZATION FOR CROHN'S AND COLITIS.
This systematic review and Brazilian expert consensus assessed biosimilar use in inflammatory bowel disease (IBD), addressing clinical, therapeutic, and economic questions.
Microperimetry Sensitivity Changes at the Functional Transition Zone and at the EZ Margins in X-Linked Retinitis Pigmentosa Treated With Gene Therapy.
This post-hoc analysis of the randomized Skyline trial examined how photoreceptor ellipsoid-zone (EZ) structure related to microperimetry sensitivity in eyes with X-linked retinitis pigmentosa treated with gene therapy.
Fetal hemothorax due to intrapleural rupture of a small anterior thoracic lymphatic malformation: a case report.
A pregnant woman was referred at 26 weeks after bloody fetal pleural fluid was obtained by thoracentesis. Ultrasound showed right pleural effusion and a small, avascular heterogeneous area in the anterior chest wall…
Drug treatments for fibromyalgia: systematic review and network meta-analysis of randomised trials.
This systematic review and network meta-analysis compared drug treatments for fibromyalgia in adults, including evidence from 151 randomised trials involving 32 592 participants.
Adult-Onset Henoch-Schönlein Purpura Triggered by Isotretinoin with Persistent Polyarthritis and Isolated Cutaneous-Gastrointestinal Involvement: A Case Report.
A 30-year-old woman developed palpable purpura, abdominal pain, and symmetric polyarthritis three weeks after starting isotretinoin.
Remimazolam ED95 for Preoperative Sedation in Children with Obstructive Sleep Apnea, with Obesity or a Reference-Range BMI: A Biased-Coin Dose-Finding Study.
Obesity may alter total-body-weight dosing of remimazolam, whereas obstructive sleep apnea narrows the respiratory safety margin.
Anaphylaxis Following Intravenous Methylprednisolone Sodium Succinate: A Case Report.
A 45-year-old woman with rheumatoid arthritis developed generalized pruritic erythema and raised lesions, dyspnea, hypoxemia, bradycardia, and reduced consciousness within 5 minutes of starting intravenous…
Impact of Side-to-Side Versus End-to-Side Gastrojejunostomy on the Rate of Delayed Gastric Emptying After Pancreatoduodenectomy (IPAD study): A Randomized Controlled Trial.
The IPAD study was a prospective, open-label randomized trial at two high-volume pancreatic centers in France, comparing side-to-side with end-to-side gastrojejunostomy in adults undergoing pancreatoduodenectomy for…
A phase III randomized study: Immunogenicity and safety of a quadrivalent meningococcal conjugate vaccine in healthy adults, adolescents, and children in India and healthy adolescents and children in South Africa.
This Phase III randomized controlled trial assessed the immunogenicity and safety of a single dose of MenACYW-TT in healthy adults, adolescents, and children in India and in adolescents and children in South Africa.
Dynamic change patterns in suicidal ideation differ in Brief Cognitive Behavioral Therapy (BCBT) and Present-Centered Therapy (PCT).
This randomized clinical trial examined how five dimensions of suicidal ideation changed during Brief Cognitive Behavioral Therapy (BCBT) versus Present-Centered Therapy (PCT) among high-risk U.S.
The utility of magnetic resonance imaging of the spinal cord in paediatric transverse myelitis: A systematic review.
This systematic review assessed spinal cord MRI findings, agreement with CSF inflammation, and prognostic associations in children with monophasic acute transverse myelitis.
Adjunctive neuromuscular electrical stimulation and cognitive-motor interference during gait in older inpatients.
This exploratory analysis of a pragmatic pilot trial examined whether adjunctive neuromuscular electrical stimulation (NMES) was associated with changes in cognitive-motor interference during gait among older inpatients…
Nutraceuticals and phytoceuticals in the treatment of bipolar disorder: A systematic review and network meta-analysis.
This systematic review and network meta-analysis assessed randomized controlled trials of nutraceuticals and phytoceuticals for bipolar disorder. Twenty-eight trials involving 2,222 participants evaluated 22 treatments.
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